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Biomedical subjects

P Fischer

Publications and source records attributed to P Fischer.

At least 397 records · Page 22Linked to original sources

[Experiences with a standardized questionnaire for determination of the vegetative lability and certain life and behavior styles in patients of internal medicine clinic].

180 students without pathological psychic findings, 233 students with psychic disturbances, 168 internal patients with vegetative disturbances and 231 patients with progressive chronic polyarthritis were interrogated with the VELA-questionnaire of Fahrenberg and the ENR-questionnaire according to Brengelmann and Brengelmann. Compared with the normal group all other groups had significantly higher VELA-values. The combination E less than 10, N greater then 26 was found in students without pathological psychic findings in 2.8%, in patients with rheumatism in 7.4%, in internal patients in 21.4% and in students with psychic disturbances in 24.1%. With this combination and another one with extreme values 5.1% of the comparative group, 9.6% of the patients with somatic diseases and approximately 61.4% of the patients with a high number of vegetative complaints are suspicious of a psychic disturbance which must be treated.

Adult↗

Technique for the visualization of exchange aberrations in human chromosomes.

A technique for the visualization of chromatid exchange in human chromosomes is described. Additon of the base analogue 5-bromodeoxyuridine (BUdR) into PHA stimulated lymphocyte cultures and subsequent staining with the benzimidazol compound "33258 Hoechst", and Giemsa, results in differential fluorescence or staining of sister chromatids in second division metaphases. This technique allows an accurate scoring of sister chromatid exchanges, and could be used in the evaluation of the effect of external agents on the induction of previously unrecognized chromatid exchanges in human chromosomes.

Chromatids↗