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Biomedical subjects

P F Bolis

Publications and source records attributed to P F Bolis.

At least 55 records · Page 3Linked to original sources
PubMed1981

A comparison of droperidol and metoclopramide in the treatment of nausea and vomiting during cis-platinum polichemotherapy in ovarian carcinoma.

A comparison was made of the anti-emetic effects of Droperidol (total dose: 5 mg e.v.) and Metoclopramide (total dose: 30 mg e.v.), on 7 patients affected by advanced ovarian carcinoma and undergoing polychemotherapeutical treatment with courses including 50 mg/mq-doses of Cis-Dichlorodiaminoplatinum (DDP). Although no significant difference was observed between the emetic-control effects of the two substances, Droperidol was preferred by all patients, owing to its subjective effects.

Antineoplastic Agents↗
PubMed1978

Treatment of hyperprolactinemic amenorrhea by intermittent administration of bromocryptine (CB 154).

The results obtained with intermittent bromocryptine treatment from the fifth day after the beginning of menstruation until the second day after the basal temperature rise, in 14 women with hyperprolactinemic amenorrhea-galactorrhea and in whom menses had previously been induced by continuous treatment, are presented. All women had menses without reappearance of galactorrhea; serum FSH, LH, estradiol, and progesterone followed a normal physiologic trend. Only prolactin rose again in the second phase of the cycle, in which lower levels of progesterone were also found, but without any significant interference in the clinical and hormonal trend. It is stressed that administration of bromocryptine during the first part of the cycle might substitute for continuous administration, thereby reducing drug consumption and hence possible side-effects as well as the cost of treatment.

Amenorrhea↗
PubMed1978

Lead in red blood cells and in plasma of pregnant women and their offspring.

Lead levels were measured in red blood cells and plasma of 75 pregnant women and their infants at delivery. No significant differences were found by comparing maternal and fetal values and a statistically significant positive correlation was evidenced, higher for plasma levels. The results suggest that the diffusible form of maternal lead in plasma influences the lead transferred to the fetus more directly. The highly significant correlation found between the maternal and fetal ratio of lead in plasma to lead in erythrocytes seems to be in favor of inborn factors influencing the equilibrium between the two compartments in which lead is distributed.

Erythrocytes↗