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Biomedical subjects

P D Ellner

Publications and source records attributed to P D Ellner.

At least 73 records · Page 4Linked to original sources
PubMed1969

New medium for blood cultures.

A new medium suitable for blood cultures is described. It contains dextrose, cysteine, iron, and magnesium, in a tris(hydroxymethyl)aminomethane buffer, and a mixture of peptones derived from animal tissues, casein, and yeast. In comparison with Trypticase Soy Broth, the growth rate constants of Staphylococcus aureus, Streptococcus (Viridans group), enterococcus, and Escherichia coli were higher in this medium, and growth appeared earlier in a significant number of clinical blood cultures.

Bacteria↗
PubMed1969

Effect of mixed cultures on antibiotic susceptibility testing.

Careful studies of the antibiotic susceptibilities of mixtures of bacteria likely to be encountered in clinical cultures have shown that the results obtained are completely unreliable. Mixtures of resistant and sensitive species appeared either as "resistant" or "sensitive" depending upon the organisms and the drug. A number of sensitive species gave reactions interpreted as resistant when tested in combination. Since reactions of bacterial mixtures are completely unpredictable, the authors emphasize that antibiotic susceptibility testing be limited to pure cultures.

Anti-Bacterial Agents↗
PubMed1968

Mutant of Bacterium paracoli 5099 with an altered DNA: identification as a Flavobacterium.

A difference in the base composition of the DNA of Bacterium paracoli 5099 and of a "mutant" (No. 1975) derived from it was found. This is in accordance with the finding of others. However, biochemical tests revealed that the "mutant" was a Flavobacterium, whereas the parent strain belonged to a species of Escherichia. The base composition of the DNA of the "mutant" is similar to that reported for the DNA of Flavobacterium.

Adenine↗
PubMed1968

System for inoculation of blood in the laboratory.

A system is described that provides for the collection of blood in Vacutainer tubes containing Liquoid (sodium polyanethol sulfonate) and for the transport of such blood to the laboratory for inoculation. The procedure is compared to one utilizing open flasks of media, and the advantages of the closed system are discussed.

Blood Preservation↗
PubMedDate not supplied

Smallpox: gone but not forgotten.

Smallpox represents both the acme of man's efforts to combat infectious diseases and one of his greatest fears. The disease emerged in prehistoric times to spread throughout the world causing blindness and death in millions of people. An acute infection caused by variola virus, one of the Orthopoxviruses, with skin eruption and marked toxemia had an average case fatality rate of 30%. Variola minor, a milder form of the disease, had a case fatality of one percent. Humans are the sole host, and survival confers lifelong immunity. Immunization was practiced since ancient times by inoculation with the variola virus until Jenner's demonstration of the efficacy and safety of vaccination with vaccinia virus. Following an intensive eradication effort by the World Health Organization, the world was declared to be free of smallpox in 1979. The decision to destroy all remaining stocks of variola virus in 1999 has met with some controversy.

Animals↗