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Biomedical subjects

P Curtis

Publications and source records attributed to P Curtis.

At least 109 records · Page 6Linked to original sources
PubMed1986

Prepartum and intrapartum breast stimulation in obstetrics. A review.

The publication of studies that describe the use of breast stimulation to produce or augment contractions before and during labor has grown rapidly over the last three years. Until recently, this physiologic phenomenon appears to have been little recognized in the medical literature, though references to the technique do appear in the medical literature from Hippocrates to the present.

Breast↗
PubMed1986

Uterine responses to three techniques of breast stimulation.

Uterine contractions produced by three methods of breast stimulation and a placebo were compared in 202 high-risk women between 35 and 44 weeks' gestation during contraction stress tests. Manual stimulation produced significantly more successful responses of three or more contractions within ten minutes than did a heating pad or a placebo, but did not show significant differences when compared with a breast pump. The placebo group showed an increase in contractions over a resting state. Of the women with successful contraction stress tests, over 50% demonstrated exaggerated uterine activity (a hypertonic contraction of greater than 90 seconds, or five or more contractions in a ten-minute period).

Adolescent↗
PubMed1985

Detection and characterization of a mouse alpha-spectrin cDNA clone by its expression in Escherichia coli.

A cloned segment of mouse alpha-spectrin mRNA has been identified by immunological techniques. Double-stranded cDNA derived from spleens of anemic mice was introduced into a bacterial expression vector, pUC, and transformed Escherichia coli colonies were screened by using an antiserum to erythrocyte membrane ghost proteins. Of 17 positive colonies, 2 bound antibody to mouse spectrin, and these 2 colonies contained 750-base-pair inserts that cross-hybridized. Transfer of the 750-base-pair insert to an expression vector containing the PL promoter of phage lambda produced larger amounts of peptides that were bound by antibody to mouse spectrin. The spectrin-like peptides made in E. coli elicited antibody that reacted only with the alpha-spectrin subunit of erythrocyte membranes. This clone will be useful for the study of the structure and expression of the spectrin gene, particularly in understanding the role of spectrin in human inherited hemolytic anemias.

Animals↗
PubMed1985

Characteristics and perceptions of after-hours callers.

After-hours care remains an important aspect of community practice although little is known about the views of either physicians or patients. This study presents an analysis of 12 499 after-hours calls made to a family practice centre over a five-year period, and 798 follow-up telephone interviews conducted with people who called for help after hours. Fifty per cent of the callers requested care for themselves while the remainder made the call for another family member, usually a child; most had discussed the problem with family or friends before calling. A majority stated that they would go to a hospital emergency room if they could not use the after-hours service. Physicians tended to perceive the calls as being due primarily to physical problems, while almost one-third of the callers stated that the motive for their call was anxiety or concern rather than physical discomfort. Although there was a lack of agreement between physician and caller on several aspects of the contact, most of the callers were satisfied with the contact.

Adolescent↗
PubMed1985

Physician decision making over the telephone.

Physician decision-making behaviors were evaluated for 31 telephone encounters between trained patient simulators and 9 first-year residents, 11 third-year residents, and 8 practicing physicians on after-hours call. The following trends occur as physicians become more experienced: mean call length decreases, less time is spent on diagnosis, fewer diagnostic questions are asked, greater time is spent on management, and diagnostic reasoning becomes more intuitive. These findings suggest that previous models of good telephone decision making, which focused on empirical data collection, may not represent the process used by experienced physicians.

Decision Making↗
PubMed1984

M13 bacteriophage vectors for the expression of foreign proteins in Escherichia coli: the rabies glycoprotein.

The expression of a protein-coding DNA fragment in a microorganism such as Escherichia coli requires that the exogenous DNA segment be inserted precisely in phase with bacterial translation initiation signals. We report the construction of derivatives of the M13 vectors M13mp7 and M13mp701 in which a HindIII site has been inserted, within the N-terminal section of the beta-galactosidase gene, in all three phases of translation. These vectors may thus be used for the expression, under the control of the lac promoter and translation initiation signals, of protein coding DNA segments flanked by a HindIII site. In all cases the insertion of a DNA fragment can be recognized by the abolition of beta-galactosidase activity. These vectors have been used to direct the expression, in E. coli, of a cDNA segment coding for the rabies virus surface glycoprotein. The proteins produced have been shown to react with antisera raised against authentic rabies glycoprotein.

Antigens, Viral↗
PubMed1983

Using patient-simulators to teach telephone communication skills to health professionals.

Using patient-simulators is an effective and inexpensive approach for teaching telephone communication skills to health professionals. An audiotaped simulation program has been carried out with the residents of the Family Practice Center at the University of North Carolina at Chapel Hill and has been implemented in several other areas, including pediatrics, psychiatry, nursing, and a third-year elective clerkship in family medicine.

Clinical Competence↗
PubMed1982

Inside the chart review.

The study on which this article is based was conducted at the University of North Carolina's Family Practice Center to analyze the content of teaching that occurred in the face-to-face chart review sessions. Data were collected from a sample of 276 chart reviews and processed by a microcomputer program that compiled reports of types of problems encountered by residents, topics of discussion pertinent to those problems, and learning needs defined as a result of those discussions. Reports were generated for faculty members nad residents, and summary reports were produced for the teaching encounters. This system of computerized data analysis can be used to identifying learning needs of residents and areas of teaching emphasis for faculty. The information can be used for educational planning and faculty development.

Clinical Competence↗