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Biomedical subjects

P Cleaton-Jones

Publications and source records attributed to P Cleaton-Jones.

At least 127 records · Page 7Linked to original sources
PubMed1976

A scanning electron microscope study of the developing rat secondary palate.

The surfaces of the developing secondary palatal shelves and palate, in Wistar strain albino rats, were examined using scanning electron microscopy. Beginning on the 16th day after insemination there was a progressive degeneration of the cell surfaces on the medial aspect of the shelves. This took the form of a loss of surface microvilli and intercellular boundaries accompanied by the appearance of clefts between the cells. Fusion of the palate was complete by the 18th day and two epithelial zones could be recognized in the soft palate. The cell surface degeneration is possibly an essential change prior to shelf fusion.

Animals↗
PubMed1976

An ultrastructural study of keratinized epithelia in the rat soft palate.

The three kinds of keratinized epithelium evident on gross examination of the soft palate of Wistar albino rats were studied by scanning and transmission electron microscopy. Scanning indicated a central area where the epithelium showed numerous fine folds and papillae, more lateral areas which were smooth, and most lateral areas with fine folds only. At high magnifications the cell surfaces were seen to be pitted with numerous small craters. However, all three epithelia had a similar appearance under the transmission electron microscope, namely that of keratinized oral epithelia. The gross surface differences probably reflect functional modifications.

Animals↗
PubMed1975

Surface characteristics of cells from different layers of keratinized and non-keratinized oral epithelia.

Portions of clinically healthy non-keratinized and keratinized oral epithelia were removed from adult vervet monkeys (Cercopithecus aethiops). The epithelium was separated from the underlying lamina propria by trypsin digestion, following which the epithelial cells were separated from the various epithelial layers. These were examined with the light and scanning electron microscope. Cells from non-keratinized epithelia have surface microplications while those from keratinized epithelia show microvilli and pits. Two distinct types of cell are therefore present. It is suggested that the different surface appearances are related to different types of mechanical adhesion between the cells.

Animals↗
PubMed1975

Blood supply in the developing and post natal rat soft palate.

Foetal and post natal rats were perfused with a carbon suspension and cleared in methyl salicylate to display the blood supply of the developing and formed hard and soft palates. The arterial blood supply of the soft palate was from the pharyngeal artery, a branch of the pterygopalatine artery; and from the tonsillar artery, a branch of the external maxillary artery. The pharyngeal artery could be recognised from 14 days post insemination and reached its adult configuration on the 17th day p.i. The tonsillar artery was seen from the 18th day. In the hard palate the blood supply was as described by other authors.

Age Factors↗
PubMed1975

Normal histology of the human soft palate.

The histology of the human soft palate seen in four whole soft palates and four mucosal biopsies has been described, with an emphasis on the elastic fibres. Striking features were the presence of much fat, thick interglandular connective tissue septa, considerable elastic tissue, and a complete absence of taste buds.

Adult↗