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Biomedical subjects

P Castaigne

Publications and source records attributed to P Castaigne.

At least 109 records · Page 6Linked to original sources
PubMed1976

[An experimental study of the psychostimulant action of amantadine].

According to previous experimental and clinical data, we have tested the hypothetic psycho-stimulating activity of amantadine on experimental sensitized models. We obtained a strong action on the spontaneous sleep of rats at a dose of 10 mg/kg and a less striking action in diminishing the effects of barbitol on the righting reflex of mice and in reducing the narcosis of rats induced by mebubarbital. This action does not seem to be due to a release of catecholamine because the lesions produced by electrocoagulation in the ascending aminergic pathways or pretreatment by alpha-methylparatyrosine (AMPT) do not block it. It is suggested that there may be a non-aminergic receptor of amantadine which is different from the amphetamine receptor.

Amantadine↗
PubMed1976

[Recurrent peripheral nerve palsies and concomitant chronic neuropathy. Neuromusclar electrophysiologic study and neuropathologic examination: apropos of 5 cases].

The authors report 5 personal cases (3 in the same family) of patients suffering from recurrent peripheral nerve palsies usually induced by pressure and review the relevant literature. There is evidence in such cases of a mild, chronic, diffuse, subclinical neuropathy which can be recognized by electrophysiological examination. Examination of peripheral nerve biopsy material in such cases shows evidence of both axonal and Schwann cell abnormalities with evidence of neurogenic atrophy of skeletal muscles. This chronic subclinical neuropathy which is often familial can be distinguished from other chronic primary neuropathies with or without myelin sheath proliferation and hypertrophy.

Adult↗
PubMed1976

[Huntington's chorea and cerebellar atrophy. Apropos of amanatomo-clinical case].

The authors report the clinical and pathological findings in a 46 years old woman with Huntington's chorea and cerebello-olivar atrophy. Eight previously reported cerebellar atrophies in Huntington's chorea with pathological examination are reviewed. The primary or secondary nature of the cerebellar lesions is discussed.

Adult↗
PubMed1976

[Meningeal arterio-venous fistulas with cortical venous drainage].

Pure dural arteriovenous fistulas are still not properly understood, and pose problems wich are far from being resolved. Among these, dural fistulas with cortical venous drainage represent a very special entity since they alone are expressed clinically by a neurological brain syndrome. Diagnosis is difficult and mistakes can be made as it is only by means of hyperselective arteriography of the branches of the external carotid that an accurate diagnosis can be made. However, their diagnosis assumes considerable importance since surgical or radiological treatment of hese fistulas brings about complete disappearance of clinical symptoms.

Adult↗
PubMed1975

[2 cases of paralysis of the posterior branch of the radial nerve due to compression of the nerve by a lipoma].

The authors report two cases of paralysis of the posterior branch of the radial nerve as a result of compression of the nerve by a benign tumour, in both instances a lipoma. Analysis of the sixteen cases appearing in the literature reveals that the symptoms and signs are constant, characterised by the progressive development of paralysis of the muscles supplied by the deep branch of the radial nerve with the appearance of a tumefaction around the lateral part of the elbow. X-rays of the elbow confirm the diagnosis in the presence of a radiotranslucent polylobulated image. Surgical excision is followed by regression and the disappearance of a-l neurological signs after an average period of 8 months. In addition to a lipoma, compression may be caused by repeated contusion of the nerve by the border of the superficial part of the short supinator muscle in association with "tennis elbow". Section of this part of the muscle border results in complete recovery.

Aged↗
PubMed1975

[Optic ataxia localised in the left side of both 2 left homonymous visual hemifields].

Ocular ataxia localised to the left limbs on the left homonymous visual hemifields occurred after section of the right parieto-occipital junction zone performed to remove an intraventricular tumour. Since the right upper limb was unaffected, it must be presumed that, in man, there are two types of occipito-frontal connections, direct and crossed.

Adenocarcinoma↗
PubMed1975

[Arteriovenous fistulae of the dura mater. Clinical and radiological study of 13 cases].

The authors studied 13 new cases of fistulae of the dura mater. With reference to these 13 cases, and to the literature, they propose a classification according to the type of drainage of the fistula: direct, into a dura mater lake, into a cortical vein. This clasification enables a better clinical and radiological approach to these anomalies.

Dura Mater↗
PubMed1975

[Multiple intracranial arterial aneurysm of mycotic appearance. Repeated vascular embolic accidents. Myxoma of the left atrium].

The authors describe a case of myxoma of the left auricle disclosed by repeated cerebral embolism and multiple aneuryms of mycotic appearance of the cerebral arteries in a woman exhibiting no cardiac symptoms. The immediate post-operative results were excellent. In the light of 7 similar cases in the literature, diagnostic and prognostic points are analysed.

Adult↗
PubMed1975

[Heterochronia of nerve fibers in man. Diagnostic value: initial results].

A classical physiological observation not usually apparent with methods used for detecting nerve potential in man, heterochronia of the nerve fibres is often found in extraordinary circumstances with considerably higher than normal frequence : mainly in muscular disorders, in particular myotonic dystrophy ; more incidentally in disorders of muscle tone. The authors draw attention to certain sources of error which could lead to wrong diagnosis of heterochronia and emphasize that these are only the initial results of research which needs to be pursued further.

Electric Stimulation↗