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Biomedical subjects

P Canton

Publications and source records attributed to P Canton.

At least 127 records · Page 7Linked to original sources
PubMed1982

[Cervical Pyoderma gangrenosum: treatment by plasma exchanges].

The authors report one case of Pyoderma gangrenosum whose unusual cervical localization was particularly bothering. Besides, the patient, an 18-year-old girl, had clinical symptoms of Crohn's disease confirmed by radiological investigations and bowel pathology. A benign monoclonal gammapathy and an auto-immune haemolytic anaemia were also found. After four plasma exchanges Pyoderma healed rapidly, Crohn's disease stabilized and biological abnormalities disappeared. Comments and review of the literature are reported. It appears that such a case is quite exceptional, as far as clinical, biological data and therapy (plasma exchange) are concerned.

Adolescent↗
PubMed1981

[Cefotaxime in septicaemia and severe infections due to multiresistant Gram-negative bacilli (author's transl)].

Cefotaxime was given to 26 patients with serious infections resistant to other antibiotics. 15 patients were suffering from septicaemia due to Gram-negative bacilli, which were caused either by a single organism (13 cases:" of which Serratia in 6, Klebsiella in 3) or by several organisms (2 cases); 7 had upper urinary tract infections (caused by Serratia in 4 patients), and 6 had miscellaneous infections (two of these were purulent post-operative meningitis). The pathogens were usually resistant to ampicillin and cephalothin. Cefotaxime was administered at a daily dose of 3 g in 22 patients, irrespective of the renal function, and of 6 g in 4 patients (2 meningitis). Treatment included an aminoglycoside in 12 cases. The efficacy of cefotaxime was very satisfactory in 23 of the 26 patients.

Adult↗
PubMed1981

[Lymphogranuloma venereum affecting simultaneously cervical and inguinal lymph nodes (author's transl)].

Nicolas-Favre's disease, also called lymphogranuloma venereum, a venereally transmitted disease caused by Chlamydia trachomatis, is usually presenting as an inguinal lymphadenopathy or an anorectal syndrome. Cervical lymph node involvement is uncommon, and in a review of the literature the authors found about fifteen such cases. The mode of transmission frequently consists of oral sexual contact. In this report, the authors describe a case of simultaneous cervical and inguinal lymph node involvement. The inguinal localization secondarily appeared, and allowed to suspect diagnosis.

Adult↗
PubMed1977

[Cerebrospinal fluid distribution of metampicillin (author's transl)].

UNLABELLED: In order to avoid other antibiotics which interfere with plasma and CSF level determination of a given antibiotic the authors use a chemical method of established specificity. 15 patients presenting with purulent meningitis were given a standard daily dose of metampicillin and divided into 3 groups of 5. On days 2, 4 and 6 after onset of disease plasma and CSF specimens were taken at respectively 1, 2 or 4 hours following metampicillin I.V. injection according to patient group. All patients were cured between days 7 and 21 of therapy. Tolerance was good. RESULTS: --there was no correlation between dose injected and plasma level of drug,--CSF distribution of metampicillin was good and stayed identical throughout the disease period,--peak CSF drug level was delayed as compared to plasma level, occurring more than 4 hours after I.V. injection of metampicillin.

Ampicillin↗