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Biomedical subjects

P Brusini

Publications and source records attributed to P Brusini.

At least 19 recordsLinked to original sources
PubMed2005

Probing glaucoma visual damage by rarebit perimetry.

AIM: To compare rarebit perimetry (RBP) with standard achromatic perimetry (SAP) in detecting early glaucomatous functional damage. METHODS: 43 patients with ocular hypertension (OH), 39 with early primary open angle glaucoma (POAG), and 41 controls were considered. Visual fields were assessed using the Humphrey field analyser (HFA) 30-2 and RBP tests. Differences among the groups were evaluated using Student-Newman-Keuls and chi(2) tests. Correlation between HFA and RBP parameters was assessed using the Pearson's correlation coefficients and regression analysis. Sensitivity and specificity of RBP in detecting early glaucomatous visual damage were calculated with different algorithms. RESULTS: RBP-mean hit rate (MHR) was respectively 88.6% (SD 4.8%) in controls; 79.1% (10.9%) in the OH group; 64.3% (13.8%) in the POAG group (differences statistically significant). Good correlation in the POAG group was found between HFA-mean deviation and RBP-MHR. Largest AROC (0.95) and optimal sensitivity (97.4%) were obtained when an abnormal RBP test was defined as having (at least 1): MHR <80%; >15 areas with a non-hit rate of >10%; > or =2 areas with a non-hit rate of >50%; at least one area with a non-hit rate of > or =70%. CONCLUSIONS: The RBP appeared to be a rapid, comfortable, and easily available perimetric test (requiring only a PC device), showing a high sensitivity and specificity in detecting early glaucomatous visual field defects.

Adult↗
PubMed2000

Corneal thickness in glaucoma: an important parameter?

Central corneal thickness was measured by pachometry in 49 patients with primary open-angle glaucoma (POAG), 41 with ocular hypertension (OHT), 14 with normal tension glaucoma (NTG) and 48 normal subjects. The mean corneal thickness of the OHT patients was significantly greater than that of the normal control group. The NTG patients, on the other hand, had a cornea on average thinner than the normals. These differences may cause misclassification of normals with a thick cornea as ocular hypertensive eyes or, contrarywise, cause those normals whose IOP is underestimated because of a thin cornea to be classed as NTG patients.

Adult↗
PubMed2000

Quantitative mapping of the retinal thickness at the posterior pole in chronic open angle glaucoma.

The sensitivity of a new device, which is able to measure the thickness of the retina at the posterior pole (Retinal Thickness Analyzer), was assessed in a group of 21 glaucomatous patients, and in 24 patients with ocular hypertension. The specificity of RTA was evaluated in a control group of normal eyes. Of the glaucomatous eyes, 57.6% had a significant reduction in retinal thickness, while another 30.3% were borderline. In the ocular hypertension group, 37.5% of eyes were abnormal, and 45.8% were borderline. In the control group, no eye was abnormal, though 42.9% had borderline alterations. In many glaucomatous eyes (81.8%) there was a relationship between retinal thickness loss and visual field defects.

Adult↗
PubMed1998

Frequency doubling perimetry in glaucoma early diagnosis.

Frequency-doubling perimetry (FDP) is a new, out-of-the-ordinary, visual field testing method. Its sensitivity and reliability was tested in 16 patients (32 eyes) with ocular hypertension and 21 patients (37 eyes) with early chronic glaucoma. Significant defects were found in almost 10% of hypertensive eyes and in 67.7% of glaucomatous eyes. FDP is an effective and sensitive technique for glaucoma functional loss assessment.

Adult↗
PubMed1997

Estimating glaucomatous anatomical damage by computerized automated perimetry.

The ability of two methods (the Glaucoma Staging System and the Functional Score index) in estimating anatomical damage from automated visual field data was studied in 100 patients with chronic open-angle glaucoma. The level of association between functional and anatomical loss (classified by cup/disk ratio assessment) was satisfactory in both systems. Both the GSS (Glaucoma Staging System) and the FS (Functional Score) could be useful for estimating and quantifying the glaucomatous anatomical damage, both in the day-to-day clinical practice and in research.

Chronic Disease↗
PubMed1992

Capsulorhexis in mature cataracts: why not?

Continuous circular capsulorhexis is now widely used in cataract surgery. In the case of mature cataract, however, this technique may be difficult due to the poor visibility of the anterior capsule. This problem can be overcome performing capsulorhexis under air. A small amount of a high molecular weight viscoelastic agent is injected near the incision, so as to avoid air escaping from the anterior chamber. Visibility is good and the handling of the anterior capsule is easy and safe.

Cataract Extraction↗
PubMed1983

Spontaneous hyphaema from persistent remnant of the pupillary membrane. A case report.

A spontaneous unilateral hyphaema in a 75-year-old woman, due to bleeding from iris vessels, a remnant of the pupillary membrane, was observed. Hyphaema was completely resorbed after 24 h. Fluorescein angiography showed the presence of a blood circulation in the anomalous vessels and a diffusion of fluorescein from saccular dilatations on the inferior vessel.

Aged↗