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Biomedical subjects

P Beaufils

Publications and source records attributed to P Beaufils.

At least 145 records · Page 8Linked to original sources
PubMed1977

[Emergency treatment of mechanical complications of acute myocardial infarction. Septum perforations and mitral insufficiency].

Over the last three years, thanks on the one hand to improvements in surgical techniques and ressuscitation, and on the other to assisted circulation using the intra-aortic balloon, which allows improved preoperative preparation of the patients, urgent medicosurgical treatment of the mechanical complications of infarction has improved the prognosis by comparison with the recent past. During the above period, our figures for operative intervention during the first two weeks after an acute infarction have been as follows: 1. Twenty nine cases of septal perforation (17 of which had previously had assisted circulation by balloon): there were 8 immediate deaths and 8 successful cases (no secondary deaths over a follow-up period of from 2 to 41 months). In all these cases, the surgeon approached the perforation by way of the left ventricle. No patient required an additional bypass procedure. Where indicated, assisted circulation by means of a balloon should not be continued for more than a few days. If there is no improvement with its use, it seems unreasonable to proceed to surgery regardless. 2. Ten cases of acute mitral incompetence; 8 were due to ruptured papillary muscle and two to mal function. 5 patients out of the 10 had required circulatory assistance by balloon preoperatively. There were 2 immediate deaths and 8 successful cases, with one secondary death (follow-up period of between 2 and 37 months).

Acute Disease↗
PubMed1976

[Acute kidney failure during periarteritis nodosa].

In 9 patients aged 16 to 71 years with acute renal failure, histological examination disclosed polyarteritis nodosa. Symptoms of rapidly progressive glomerulonephritis (GN) were present in 7 cases. Hypertension was a constant feature. Fever and muscular articular and cutaneous signs occured at times simulating Henoch-Schönlein purpura. Necrotizing angiitis was a constant finding, with perivascular granuloma in 7 cases. Lesions affecting smaller arteries were associated with diffuse or segmental extracapillary GN, and lesions of larger arteries with ischaemic appearance of the glomeruli. Diagnosis was obtained during life by percutaneous renal biopsy in 5 patients and muscular or cutaneous biopsy in 2 other patients, whereas the evidence was only obtained on post mortem examination in the 2 remaining patients. In the 6 renal biopsies examined by immunofluorescence, fibrinogen was always present in glomeruli and/or arteries. In one patient there was a linear deposit of IgG along glomerular basement membrane (GBM) and there were circulating antibodies directed against GBM. Arteries of different sizes may be damaged in various organs, as showed by arteriography and autopsy. Steroid therapy and immunosuppressive drugs had no effect on renal symptoms. 8 out of 9 patients died rapidly, in 6 the death was due to extrarenal localization of the disease, even though uraemia was controlled by haemodialysis. The last patient died 2 years after onset of the disease, while being on maintenance haemodialysis treatment.

Acute Kidney Injury↗
PubMed1976

[Temporary mechanical cardiocirculatory assistance in an adolescent suffering from subacute cardiac failure].

A case is reported of subacute carciac failure during the course of a non-obstructive cardiomypathy in an adolescent. When the exacerbation of cardiac failure, which was accompanied by severe arrhythmias, failed to respond to medical treatment, the combination of a veno-arterial bypass and membrane oxygenator with diastolic counter-pressure from an intra-aortic balloon was tried with success. A reasonable remission was obtained by this means, but the young patient died 8 months later from cardiac failure which proved resistant to treatment.

Acute Disease↗
PubMed1976

[Isolated ventricular tachycardia without patent cardiopathy].

The authors have made a further study of the case notes of 49 patients who were followed up for several years with isolated ventricular tachycardia occurring in a heart which was otherwise healthy; such tachycardias are also called essential or idiopathic. First they define the criteria necessary for the diagnosis of essential ventricular tachycardia: -- an arbitrary age criterion (less than 45 years in men and 50 years in women) which seeks to exclude the so-called "arterial" ventricular tachycardias; -- a follow-up period of supervision of more than two years, which excludes certain primary cardiomyopathies whose presenting feature is a series of attacks of ventricular tachycardia. They then attempt to classify the ventricular tchycardias into four types, according to their clinical features and the electrocardiographic tracings at rest and on exercise, and to predict the prognosis. The most frequently encountered and benign type was the classical ventricular tachycardia of Bouveret.

Adolescent↗
PubMed1975

[Wave bursts].

Explore the source record for details and available documents.

Arrhythmias, Cardiac↗
PubMed1975

[Acute bacterial endocarditis].

Acute endocarditides, defined by the intensity of the infectious syndrome, increase rapidly in incidence, both in absolute number and in relation with classical subacute endocarditides. 60 cases were studied out of a lot of 130 cases of bacterial endocarditides. They are characterized by the nature of the portals of entry, particularly in hospital, the nature of the causal germs (staphylococci and gram-negative germs essentially), their habitually primary character, the importance of embolic manifestations. Cardiac failure through valvular mutilation is common, but surgical valve replacement is not always possible in view of the visceral or infectious context. Their overall prognosis is a very bad one: lethality 67 percent as against 15 percent for subacute endocarditides. An important part of prevention lies in a better hospital hygiene.

Acute Disease↗
PubMed1975

[Dressler's syndrome: constrictive pericarditis following myocardial infarction operated on with success].

In relation with one case of constrictive pericarditis folowing myocardial infarction, the respective part played by the Dressler syndrome and by the anticoagulant treatment in the genesis of pericardial constriction was discussed. In presence of an inflammatory pericardial reaction after myocardial infarction, the rules for the use of anticoagulants are discusses.

Adrenal Cortex Hormones↗
PubMed1975

[Septal perforation of myocardial infarct. Progress and limitation of current treatment. Apropos of 28 recent cases].

The emergency treatment of septal perforation in a myocardial infarction was markedly improved by pre-operative preparation of the patient by an intra-aortic balloon. If one excludes 7 cases in which the favourable immediate course made possible a delayed operation, 21 cases, severe from the start, were observed in the last two years: 8 patients, were thought to be operable with 6 successes. The type of the patient, the age, the associated diseases, the gravity and extension of the local lesions explain that this complication nevertheless still remains very often beyond the present possibilities of the medical-surgical treatment.

Aged↗