Levodopa and orphenadrine hydrochloride in Parkinsonism.
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Biomedical subjects
Publications and source records attributed to P Armitage.
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The use of the hypergeometric distribution in calculations of sample volumes for safety testing is criticized. Alternative interpretations of the concept of ;infective ml. doses' lead to slightly different solutions, the simplest of which, involving the exponential function, is recommended for general use.
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A double-blind cross-over trial of emepronium bromide (Cetiprin) in nocturnal frequency of micturition in a group of elderly women living in their homes showed that the drug was superior to placebo in diminishing urinary frequency, though not every person benefited. It is suggested that the drug may alter the established habit of rising at night to pass urine. Side-effects were negligible.
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