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Biomedical subjects

P Arlet

Publications and source records attributed to P Arlet.

At least 109 records · Page 6Linked to original sources

[Pubic and ischio-pubic osteitis. Bacteriological and histopathological study of the pubic bone].

The authors present 11 cases of pubic or ischio-pubic osteitis of which ten had undergone bone biopsy by aspiration, needle biopsy, or surgery. In 7 cases, a germ was isolated by culture of the bone sample. In 2 cases, there were purulent and necrotic lesions on pathological examination of the fragment. In 6 cases, the bony lesions were mainly of the marrow with fibrosis and lymphocyte-plasma cell infiltration. In 5 of these 6 biopsies, the bacterial culture was positive. This subacute mononuclear osteitis may thus be a variety of bacterial osteitis. All the patients were treated with antibiotics which seemed necessary.

Adult↗

[Adult coeliac disease and very high IgA plasma level (author's transl)].

The authors report a case of malabsorption syndrome with jejunal atrophy in a 63 years old woman. Coeliac disease was suspected from clinical and histological features, clinical evolution with diet, and presence of HLA B8 antigen. However, this case was very particular because the infiltration of lamina propria was very dense and especially composed of plasmocytes, and because there was a very important and polyclonal rise of immunoglobulin A (32 g/L) in the serum. A review of the literature allows to consider the immunopathology of coeliac disease. Such a case was never found among the adults. Two similar observations have been described in children.

Adolescent↗

[Pulmonary mucormycoses (author's transl)].

Mucormycoses are rare, acute infections, most often fatal, occurring usually in a host with decreased immunity. The agents are ubiquitous fungi belonging to the Mucoraceae family, an ordinary saprophyte becoming pathogenous in patients with a severe disease (malignant hemopathy, diabetes) or treated by immunosuppressive drugs. Pulmonary localizations remained exceptional (128 cases found in the literature). The observations reported draws its originality from: -- the etiological circumstances: an aged patient with no hemopathy or diabetes, without immunosuppressive treatment but undergoing a prolonged antibiotic therapy; -- the clinical signs: discovery on X-ray of excavated infiltrates in a background of a severe infection with a very poor physical condition; -- the diagnosis criteria with the demonstration of the responsible mucor in the sputum, the endobronchial aspiration and transparietal puncture; -- the great efficiency of Amphotericin B at rather small doses. A review of the literature underlines the exceptional character of the cure.

Aged↗