Biomedical subjects
Publications and source records attributed to O Tokunaga.
The present case is an autopsy case of a 66-year-old male who developed a collision tumor in the stomach which originated from carcinosarcoma of Borrmann type II in the gastric antrum and from papillary adenocarcinoma of Borrmann type III in the corpus. The carcinosarcoma consisted of tubular carcinoma and sarcomatous transformation of stroma from the carcinoma.
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The effects of lidocaine in doses of 2.0--6.0 mg/kg with intravenous injection on optokinetic nystagmus were observed in 21 rabbits. No effect of lidocaine was obtained on the frequency of OKN. On the other hand, the amplitude of OKN in lidocaine groups decreased after the injection. The mode and place of the action of lidocaine on OKN were discussed.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The influence of linear acceleration on optokinetic nystagmus (OKN) was studied in human subjects. Linear acceleration was applied to the subjects by means of the parallel swing and also by the transfer of the subjects in one direction, either right or left. The cortical form of OKN increased the frequency, amplitude, and eye speed of the slow phase. Of the three, the increase in eye speed was the most pronounced. The subcortical form of OKN was not only increased but was also disturbed by the linear acceleration. When the compensatory eye movement with linear acceleration and the slow phase of OKN were in the same direction, the nystagmus increased remarkably. Contrarily, when the two directions were opposed to each other, nystagmus was inhibited. These results proved that the otolithic organs are not only able to promote but also to inhibit visual function.
The influence of vestibular stimulation by subliminal pendular rotation on the optokinetic nystagmus in normal human subjects is discussed. Cortical OKN with pendular rotation was promoted in three indexes--eye speed, frequency, and total amplitude. The subcortical OKN increased markedly when the slow phase of OHN and the compensatory eye movement resulting from the pendular rotation were in the same direction. However, it was inhibited when the two directions were mutually opposed. From the results obtained in the present experiment and in the previous study by the author, it can be concluded that the vestibular organs' effect on visual function is not only promotive but also inhibitive.