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Biomedical subjects

O Sato

Publications and source records attributed to O Sato.

At least 235 records · Page 13Linked to original sources
PubMed1982

[Therapeutic effects of cefotiam in biliary tract infections].

As useful antibiotics for biliary tract infections, smooth transmigration to lesion and potent antibacterial activities will be demanded. Usually the antibiotics having potent antibacterial activities against E. coli and Klebsiella, which are considered to be main causative organisms of biliary tract infections, will be used for treatment. The concentrations of cefotiam (CTM) in bile and gallbladder wall tissue were investigated, and CTM showed very high concentrations in these tissues for several hours. And very good correlation between concentration of CTM in bile and laboratory findings, especially ICG R15 value, was obtained. CTM showed also very potent antibacterial activities against E. coli and Klebsiella. These results suggest that CTM will be useful agent for the treatment of biliary tract infections.

Adult↗
PubMed1982

[Fracture of the sella turcica--a case report and review of the literature].

The incidence of a fracture of the sella turcica is reported to be rare and the authors reported a case of a sellar fracture associated with several neurological and endocrinological complications. A 16-year-old boy was struck at the face and the forehead on the road in a motorcycle accident and was hospitalized in a confusional state. Neurological examinations showed dilatation of the both pupils, sluggish light reflex on both sides and bilateral oculomotor palsy but motor weakness or sensory disturbance was not present. On the tenth hospital day, he developed diabetes insipidus and endocrinological examinations disclosed the impairment of GH, LH and FSH reserves, too. Neuroradiological examinations disclosed fractures of bilateral frontal bones and fractures of the left optic canal and ethmoidal roof as well as a fracture of the sella turcica. On the 28th hospital day, he also developed CSF rhinorrhea and pneumocephalus. Surgical repair for the CSF rhinorrhea was performed. Fractures of the sella turcica were reviewed in 23 cases including our personal case and a special consideration regarding the mechanism of sellar fractures and their major complications was made. The authors stressed the early recognition of a fracture of the sella turcica in head injuries, which would suggest a severe hypothalamo-pituitary involvement or other neurological disorders.

Adolescent↗
PubMed1982

[Anomalous ophthalmic artery-case reports and review of literature (author's transl)].

Case reports and review of literature were performed concerning anomalous or normal variant ophthalmic arteries discovered by angiography. In five cases, we recognized three types of the variation of the ophthalmic artery on serial magnification carotid angiograms. In the first type (case 1, 2), the middle meningeal artery originated from the ophthalmic artery. In the second type (case 3, 4) the ophthalmic artery originated from the middle meningeal artery. In the third type (case 5), double ophthalmic arteries originated from the cisternal portion and the cavernous portion of the internal carotid artery (ICA). The ophthalmic artery originating from the cavernous portion of the ICA entered the orbit through the superior orbital fissure and had a small branch to the foramen rotundum. In the first and second type, the stapedial artery was considered to play an important role in the formation of anomalous ophthalmic arteries. In regard to the third type, Lasjaunias called the ophthalmic artery from the cavernous portion of the ICA as the deep recurrent ophthalmic artery or the inferolateral trunk of the ICA. It's artery was the dorsal ophthalmic artery in a fetal period which had migrated caudally from the cisternal portion of the ICA to the cavernous portion. But Padget gave another explanation. She described that the inferolateral trunk of the ICA called by Lasjaunias was the primitive maxillary artery and the dorsal ophthalmic artery did not migrated to the cavernous portion. The origin of the ophthalmic artery originating from the cavernous portion of the ICA in the third type should be further analysed embryologically.

Adult↗
PubMed1981

[Abdominal complications of V-P or L-P shunt operation --a bowel perforation and historical review (author's transl)].

We have experienced a case of shunt tube perforation into the transverse colon in which a Pudenz infantile V-A shunt tube was installed for a hydrocephalic baby. The shunt operation was performed at a year and one month of his age in this patient and bowel perforation was disclosed and corrected twenty months following the operation. From a retrospective point of view, however, slight sign of meningitis could be suspected two months earlier and judging from his symptoms of transient intracranial hypertension, the bowel perforation might be traced back even earlier. In the past twenty year history of V-P shunt maneuver, quite a number of papers on various kinds of specific complications have been reported. On reviewing these reported cases out of English and Japanese literature, numerous abdominal complications such as twenty-eight perforations, fifty CSF ascites or pseudocysts, three umbilical perforations, two vaginal perforations, five migrations into scrotum, and some volvulus and bladder perforations can be collected. These are summarized and discussed briefly in this paper.

Ascites↗
PubMed1981

[Mechanism of suppression on cellular immunity in experimental brain tumor rats (author's transl)].

The mechanism of the suppression on the cellular immunity was analysed in experimental brain tumor rats. The tumor used in this experiment was a 3-methylcholanthrene induced fibrosarcoma. The tumor cell was inoculated into the caudate nucleus of the rats with a Hamilton microsyringe. When spleen cells from brain tumor rats were added to the PHA blastogenesis system, impairment of the normal lymphoproliferative response to the PHA was detected as early as on the third day and continued until the ninth day after inoculation. After the depletion of glass adherent cells, the residual cells from the spleen could not suppress the normal lymphoblastogenesis by the PHA. After the depletion of T cells by anti-T cell sera and complement, however, the residual cells from the spleen still suppressed the normal lymphoblastogenesis. Glass adherent cells were able to phagocyte the latex particles. From these findings, the suppressor cell responsible for the suppression of the normal lymphoblastogenesis by the PHA was considered to be macrophage and suppressor T cell did not play a role in the suppression of the PHA responses in this experimental model. The sera from brain tumor rats could not inhibit the proliferative responses of lymphocytes to PHA. Thus the possibility of the existence of suppressive factors in the sera was also negligible.

Animals↗