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Biomedical subjects

O Dapunt

Publications and source records attributed to O Dapunt.

At least 127 records · Page 7Linked to original sources
PubMed1981

[Functional disturbances of the lower urinary tract following radical surgery for cervical cancer (author's transl)].

1972 to 1977 141 patients at the university department of gynecology and obstetrics in Innsbruck had radical abdominal hysterectomies according to Latzko because of carcinoma of the cervix uteri state I-IIa. 111 (78.8%) patients without recurrence of carcinoma were investigated without recurrence of carcinoma were investigated in the period of 2 to 36 months after operation in a modern urodynamic testing unit to state functional troubles of the lower urinary tract. We judged the sensibility of the bladder, the incidence of urinary incontinence, residual urine determinations and the frequency of infections of the lower urinary tract after radical hysterectomies. In particular we were interested in the urodynamic investigation (spontaneous flow rate and uroflow-metrie after bladder filling, liquid cystometry and simultaneous measurement of the pressure in the rectum for a faithful expression of the detrusor pressure). Based on these investigations we could indicate a typical type of troubles after radical abdominal hysterectomies, which partly depends on lesions of the autonomous nerval system of the lower urinary tract. 89.5% of all these patients within the first year after operation could not feel any desire to void although the bladder was full. Longer than one year after operation we could find the same symptom in 45.5%--recovery in part seems to be possible. Moreover we could find unnoticed urinary loss, residual urine and infections of the lower urinary tract (24.7%) in higher incidence compared with a control group. Because of our investigation we could work out advice for prevention and therapy of functional troubles of the lower urinary tract after radical abdominal hysterectomy.

Female↗
PubMed1980

[Breech Presentation--a problem of prematurity? (author's transl)].

The single breech deliveries at the Universitäts-Frauenklinik Insbruck from 1973 to 1977 have been reviewed. Related to a total number of 10.693 deliveries 390 children (3.6%) were born in breech presentation. The unselected perinatal mortality rate of infants in breech presentation was 7.0% which is 4 times higher than the total infant mortality (1.6%). This seems to be due to the higher prematurity rate with breech presentation compared to all deliveries (22.6% versus 8%). In 1977 only premature breeches have been lost. The perinatal mortality rate of premature infants with breech presentation is higher than those of premature babies with vertex presentation (26.3% versus 9.8%). Therefore, more care is needed for the prevention of premature labour in breech presentation. The Caesarean section rate because of breech presentation increased from 18% (1973) to 40% (1977); nevertheless the perinatal mortality rate couldn't be reduced. Up to the present we have been afraid of deliver large series of premature breeches by Caesarean section. Maybe that therefore the perinatal mortality rate couldn't be reduced. However, according to our results routinely performed Caesarean section with mature breeches is not justified. In our opinion a decrease of perinatal morbidity and mortality only can be obtained by reducing the premature breeches.

Acidosis↗
PubMed1979

[Papillomatous changes in the cervix uteri].

A case of condyloma acuminatum of the uterine cervix and a case of papilloma on the cervix with concomitant adenocarcinoma of the cervix are described. The diagnostic biopsy revealed only the papillomatous lesion, whereas the adenocarcinoma was diagnosed in the surgical specimen after hysterectomy. Referring to the studies of Meisels et al. on condylomatous lesions of the cervix, the possible frequent incidence of this cervical lesion and its role as one possible first step in the pathogenesis of cervical cancer are discussed. The in toto excision is recommended because of diagnostic and therapeutic reasons. Clinical, colposcopic and cytologic check-up has to be done carefully for years after primary treatment.

Adenocarcinoma↗
PubMed1979

[Caesarean section: low transverse (pfannenstiel) or midline incision? (author's transl)].

In 67 elective Caesarean sections and 70 emergency sections the effect of the duration of anaesthesia upon the condition of the newborn was examined. The induction-delivery time (IDT), the operation time (OT), and the difference between these, delta t, were correlated with the 1-, 5- and 10-minute Apgar scores and the pH's of the venous and arterial umbilical cord blood. A highly significant negative association was found for the pH in the umbilical vein and delta t in the series of primary sections. Analysis of the emergency sections showed a negative association between the operation time and the 5 minute Apgar score, and a positive association between the delta t and 1 minute Apgar score. Despite these findings we have observed that the induction-delivery time which we are able to achieve in our hospital has no negative effect upon the biochemical condition (pH) of the newborn. A comparison of 619 sections performed by low midline incision with 328 section by Pfannenstiel incision showed no difference with regard to postoperative complications such as disturbance in wound healing or haematoma formation. In conclusion, with respect to the IDT and postoperative complications we have found no contraindication to the use of the low transverse Pfannenstiel incision for Caesarean section.

Apgar Score↗
PubMed1979

[Diagnosis of poor intrauterine fetal growth in twin pregnancies (author's transl)].

In 11 cases both twins were of normal weight. In 7 cases one twin and in 12 cases both twins were underweighed (the growth retardation was classified according to the intrauterine growth curves after Hohenauer applicable to our area). The determination of total 24 hours urinary estrogens and serial ultrasonic measurements of biparietal diameters appeared in our study to be the best parameters for the detection of intrauterine growth retardation. Serum HPL determination was unreliable. In addition 2 types of growth retardation in twins could be recognized from the estrogen values. In one, a dysfunction of the fetoplacental unit existed; in the other, the etiology of the growth retardation could not be determined by the methods used in the study (genetic origin?).

Birth Weight↗
PubMed1978

[Determination of the heart minute volume by impedance cardiography: a way to prophylaxis of premature birth? (author's transl)].

30 gravid women between the ages of 18 and 38 years who had gone into premature labour of unknown etiology were examined with respect to cardiac output and various other cardiovascular parameters in the standing, supine and left lateral positions. Measurements were carried out using an impedance-cardiography. A group of 30 women of similar age and duration of pregnancy but not in premature labour was also tested as controls. In the standing position, the test group showed a cardiac output which was 15% less than that of the controls. Statistically this was highly significant (p less than 0.005). No difference was found in the supine and left lateral positions. These results are in agreement with the literature, but with the method used in this study, an invasive, or X-Ray procedure is avoided. The physiology of the cardiovascular system in pregnancy and the means by which premature labour may be prevented, are discussed.

Adolescent↗
PubMed1978

Vitamin B6 nutriture during pregnancy.

The vitamin B6 nutriture was determined during pregnancy beginning at month II until term by means of determination of pyridoxal phosphate in serum of 16 healthy pregnant women. During pregnancy, a biochemical vitamin B6 deficiency occurs gradually. The most significant decrease of pyridoxal phosphate parallels the time of most intensive growth and energy retention of the fetus. Vitamin B6 nutriture of mothers at the onset of pregnancy as well as the decrease of pyridoxal phosphate during pregnancy are in a positive correlation with birth weight of newborns. The most important mechanism leading to maternal vitamin B6 deficiency seems to be the active diaplacental transport of pyridoxal phosphate from mother to fetus. A vitamin B6 supplementation during pregnancy is necessary.

Birth Weight↗
PubMed1977

[The development of the perinatal mortality at the university department for women in Innsbruck from 1969 to 1975 (author's transl)].

In a retrospective study the development of the perinatal mortality at the University Hospital for Women in Inssbruck was reviewed. Among a total of 14,839 deliveries, 323 perinatal deaths according to the WHO definition were reviewed. The years from 1969 to 1971 prior to the introduction of intensive monitoring and the years 1972 to 1975 after the introduction of monitoring were compared. The perinatal mortality was reduced from 27.7 per 1000 in 1969 to 13.7 per 1000 in 1975. The decrease was due to intensive monitoring during labour. The Caesarean Section rate rose from 3.17% in 1969 to 8.53% in 1975. The increase was mainly due to fetal indications. Conditions which were of special obstetric interest in the context of intensive antenatal care were especially reviewed. It was surprising the preeclampsia accounted for the same number of perinatal deaths in the second portion of our review as in the first. Prematurity accounted for 60--70% of the perinatal mortality and received the focus of the efforts to reduce the perinatal mortality. The perinatal mortality of infants with a birth weight of less than 2500 grams was reduced from 224.0 per thousand in 1969 to 140.0 per thousand in 1975. This result was obtained by excellent co-operation with the pediatricians. The rate of premature deliveries remained unchanged at between 8 to 9% inspite of all efforts. The possible causes for this phenomenon are discussed. The perinatal mortality was higher in cases who had antenatal care by obstetricians and general practitioners not affiliated with the University Department. The timely referral of high risk cases to a regional perinatal centre is stressed again.

Austria↗
PubMed1977

[Vaginalcytology and late pregnancy (determination of term, fetal monitoring, correlation with hormon patterns) (author's transl)].

The "before term" pattern allows to exclude over-maturity with probability of 95--100%. The "at term" pattern lets expect spontaneous labour in next five days just so with great probability. We attribute no importance to cytology as a method of control for high risk pregnancies. At last we didn't find any correlation with statistical methods between the alterations of the cell patterns some days before delivery and values of hormons.

Female↗
PubMed1976

[The problem of Caesarean section (author's transl)].

The Caesarean sections at the Universitäts-Frauenklinik Innsbruck from January 1st, 1969 to December 31st, 1974 have been surveyed. Related to the total number of 12 579 deliveries 627 Caesarean sections have been performed. Two 3-year-intervals have been compared: 1969-1971 (group I) without and 1972-1974 (group II) with modern practices of prenatal supervision. There was a high significant increase of the section rate in group II (5,8% versus 4,1% which has been related to the increasing number of mainly fetal indications. The maternal morbidity didn't rise with the increasing section rate. A significant decrease in total infant mortality rate and mortality rate at vaginal deliveries has been found with the increasing incidence of Caesarean sections; whereas the number of depressed infants (Apgar score less than 7) was increased in group II. The reasons therefore have been discussed. The rise of the number of Caesarean sections in group II performed because of breech presentation (14,2% versus 6,2%) was correspondent with a statistically significant decrease in the mortality rate from 11,7 to 4,1%. A Caesarean section rate between 7% and 10% seems to be the limit at least in our hospital--the total infant mortality rate cannot be reduced by further increasing the section frequency: the infant mortality rate possibly could be lowered by a better and more wide spread prenatal care especially by taking more care for prematurity and by intensifying the perinatal period.

Apgar Score↗
PubMed1975

[Vitamin b6 depletion in women with hyperemesis gravidarum (author's transl)].

The serum pyridoxal 5-phosphate (vitamin B6) level was measured in 20 women with hyperemesis gravidarum before and after therapy with vitamin B6. Control specimens were obtained from 22 healthy pregnant, women during the first trimester, 18 healthy prgnant women during the last trimester and from 29 healthy non-pregnant women of comparable age. The determinations were performed by means of decarboxylation of L-tyrosine-1-14 C.

Female↗