Down but not out.
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Biomedical subjects
Publications and source records attributed to Nigel Williams.
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Expansion of the EU now looks set to take place but the major efforts to develop common policies continue to be stymied by national differences, no more so than in on the issue of genetically modified (GM) crops, as Nigel Williams reports. But other moves are aiming to draw together Europeans in an effort to exploit closer collaboration as Michael Gross reports below.
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Juvenile hyaline fibromatosis (JHF) is an autosomal recessive condition characterized by multiple subcutaneous nodular tumors, gingival fibromatosis, flexion contractures of the joints, and an accumulation of hyaline in the dermis. We performed a genomewide linkage search in two families with JHF from the same region of the Indian state of Gujarat and identified a region of homozygosity on chromosome 4q21. Dense microsatellite analyses within this interval in five families with JHF who were from diverse origins demonstrate that all are compatible with linkage to chromosome 4q21 (multipoint LOD score 5.5). Meiotic recombinants place the gene for JHF within a 7-cM interval bounded by D4S2393 and D4S395.
With the number of patent claims including DNA sequence booming, is there a way forward to help resolve disagreements over the many issues involved? One ethical body believes that there is and has produced a new study.
With developments in genetics, researchers are increasingly able to address historical issues surrounding human migration and provenance by studying present populations. Nigel Williams reports on one of the latest studies looking at a crucial period of British history.