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Biomedical subjects

N Shioya

Publications and source records attributed to N Shioya.

At least 37 records · Page 2Linked to original sources
PubMed1989

Postoperative sequelae of augmentation mammaplasty by injection method in Japan.

Postoperative sequelae of 696 cases following augmentation mammaplasty by the injection method have been studied. The most frequently used foreign material for injection was silicone. Paraffin had been previously used somewhat less frequently. Of the 696 cases studied, the most common complications were hardening, skin change, transformation, and pain. Of the total number of cases studied for removal of the foreign material, 244 were seen in university hospitals and 416 in private clinics. Reaugmentation was performed in many cases using both a flap technique and bag prostheses with no significant degree of incidence of complications following reaugmentation.

Breast↗
PubMed1988

The role of psychiatry in aesthetic surgery.

Twenty-five patients seeking aesthetic surgery were investigated and treated with the cooperation of the plastic surgeon and a psychiatrist. Three-fourths of the patients revealed psychiatric problems in their backgrounds. On the recommendation of the psychiatrist, eight cases underwent operations, in spite of psychiatric problems, and were satisfied with the treatment. Patients not operated on had been persuaded to abandon their operation after psychiatric therapy. In conclusion, the cooperation of the psychiatrist was found to be very effective in the treatment of those seeking aesthetic surgery.

Adult↗
PubMed1988

A case of Hodgkin's disease arising from an intraglandular lymph node in the parotid gland.

Malignant lymphoma of the parotid gland region, especially Hodgkin's disease of the gland, is an extremely rare disorder. We have recently experienced a case initially suspected of being pleomorphic adenoma and later, on postoperative histopathological examination, diagnosed as Hodgkin's disease. The present report describes this case of Hodgkin's disease arising from an intraglandular lymph node in the parotid gland.

Adult↗
PubMed1988

Orbital lipoma.

A patient who had a huge orbital lipoma with extension to the muscle cone is described. The lipoma was 42 x 34 x 32 mm in size, and there was no visual disturbance following removal of the tumor and iliac bone grafting. Diagnosis of orbital lipoma is difficult to make. This is particularly true of a lipoma with an obvious capsule, which cannot be easily differentiated from a dermoid cyst. However, computed tomography scanning is useful in ascertaining the location, size, and relationship with orbital contents. A review of the literature concerning orbital lipoma revealed only a few reports, and the features of the orbital lipoma are summarized. In addition, the possible mechanism of orbital enlargement and the approach to the muscle cone are described.

Adult↗
PubMed1988

Biological evaluation of burn blister fluid.

Human dermal fibroblasts were cultured with blister fluid and 3 of their properties were investigated: cell shape, growth rate, and ability to contract collagen fibrils. In the medium containing the blister fluid, fibroblasts became attached to the tissue culture plastic and became well elongated to a spindle form. The blister fluid demonstrated a potent fibroblast growth-promoting activity comparable to that observed in the serum obtained from the same patient. This activity was independent of the patient's age and the time elapsed since the burn. The growth rate of cells increased as the concentration rose to 20% in the case of serum. Growth promotion by the blister fluid, however, was maximum at the concentration of 2.5%, leveling off thereafter, a fact which suggests the presence of some other factor possessing an inhibitory action on fibroblast growth. The growth-promoting activity of the blister fluid was not destroyed by tryptic digestion. The blister fluid promoted a fibroblast-mediated contraction of collagen fibrils to an extent comparable to that of the serum. The protein-banding pattern of the fluid, obtained by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate, was similar to that of the serum. These results suggest that the fluid is an exudate mainly from the vascular system, that is provides a good environment for the fibroblasts in the damaged site, and that it facilitates the healing process.

Adolescent↗
PubMed1988

A simple sternal turnover procedure using a vascular pedicle for a funnel chest.

We have improved the sternal turnover surgical procedure by using a vascular pedicle for a funnel chest. Rather than performing a simple sternal turnover, we thought it better to use the sternum with the vascular pedicle attached, anticipating that this would lead to fewer postoperative complications and a more desirable result. The following method for performing the operation was devised: (1) cutting the deformed sternum at the second intercostal position; (2) cutting the second costal cartilages to allow a repositioning of the vascular pedicle onto the presternal surface; (3) turning the sternum over, placing one end on the other, and attaching one end to the other; and (4) making a groove in the turned-over sternum to prevent the decussated vascular pedicle from becoming constricted. By using this method, it is easily possible to keep the bilateral internal thoracic vessels intact. We used this surgical technique on a 17-year-old boy and obtained very favorable results.

Adolescent↗
PubMed1985

The fate of free omental transfers.

The authors have carried out six free omental transfers for the treatment of two chronic ulcers, two progressive hemifacial atrophies, one precancerous disorder and one contused wound. The follow-up periods ranged from 3 years 9 months to 7 years 7 months. From our experience the transferred omentum maintained its volume and nature under normal circumstances. The decrease in volume or atrophy of the transferred omentum may be caused by panniculitis of the omental fatty tissue or narrowing of the anastomosed vessels.

Adolescent↗
PubMed1985

Comparative studies on methods of isolating rat epidermal cells.

Epidermal basal cells have been prepared using trypsin or dispase to remove the epidermal sheet from the skin. In addition, for trypsin, the "immersion method" and the "flotation method" have been described. However, there has been no study that quantitatively compares these methods using the same animal, making their usefulness difficult to evaluate. In this report, comparative studies on these methods were undertaken concurrently with newborn and adult rats. The flotation method using trypsin was found to be preferable to the immersion method, because separation of the epidermal sheet by the former method was easier than by the latter. Then, the flotation method using trypsin was compared with the isolation method using dispase, and quantitative estimation was made of the yield, viability, and the number of attached epidermal cells. The dispase method was found to be superior to the trypsin method, especially for cell yield, which was about four times as high as with the latter method. Furthermore, cells dissociated with dispase showed a higher rate of viability and attachment to culture dishes than those done with trypsin. These results clearly demonstrated that the dispase method is more useful for preparing epidermal basal cells than the trypsin method.

Animals↗
PubMed1984

Collagen-dependent growth suppression and changes in the shape of human dermal fibroblasts.

This study was designed to investigate the effects of collagen on the growth and cellular shape of cultured human fibroblasts. The fibroblasts grown in the presence of collagen assumed a slim, rod-like form with abundant cytoplasmic protrusions, while the cells on a plain dish showed flat forms with fewer cytoplasmic protrusions. Incorporation of [3H]thymidine was remarkably suppressed in the cells grown on collagen when compared with the fibroblasts on the plain dish. Specific cellular shape and suppressed DNA synthesis showed dependence on the steric conformation of native collagen, because collagen-specific effects on fibroblasts were completely abolished when 60% of the helix content was lost by heat denaturation. These collagen-dependent features of the cells disappeared when the collagen-containing medium was treated with bacterial collagenase. Growth of fibroblasts in contact with collagen was suppressed as compared to that on the plastic dish. These results indicate the importance of the native conformation of collagen in the interaction of collagen and fibroblasts.

Animals↗