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Biomedical subjects

N Satz

Publications and source records attributed to N Satz.

39 records · Page 3Linked to original sources

[Prevalence of hypertension and borderline hypertension in students. Comparison with a non-student group].

A blood pressure detection program was conducted at the University of Zurich in June 1978. Three consecutive blood pressure measurements using random-zero mercury sphygmomanometers (n = 4) were performed in 1364 students and 440 other subjects by 8 different investigators. Height and body weight were also measured and used to calculate the body mass index (Quetelet index). Personal history, physical activity, smoking and dietary habits were analyzed with the aid of a questionnaire. In comparison to initially measured values, there was a statistically significant decrease in systolic and diastolic pressure readings as the trial proceeded (p less than 0.001). Based on the mean value of all three measurements, hypertension was observed in only 1.7% of the male and 0.9% of the female students. In the other subjects covered by the trial the comparable values were 7.9% in males and 4.5% in females. The true prevalence of hypertension (addition of those persons with normotensive blood pressure values and simultaneous antihypertensive therapy) was 1.9% in male and 1.1% in female students, whereas 12.0% of the male and 8.5% of the female non-students suffered from hypertension. The prevalence of border-line hypertension (mean value of all three tests) was 7.4% in male and 3.0% in female students. Corresponding values for the other subjects tested were 18.7% (males) and 11.6% (females).

Adult↗

[Left ventricular function in hypertension treated with beta blockers].

In 14 patients with essential hypertension, left ventricular function was assessed echocardiographically before and after 4 and 8 weeks of treatment with the betablocking agent atenolol. Atenolol was given orally in a dose of 100 mg/day. After 4 weeks of treatment systolic blood pressure decreased from 160 to 138 mm Hg(p less than 0.001) and diastolic pressure from 105 to 91 mm Hg(p less than 0.001). Heart rate decreased from 76 to 64 beats/min (p less than 0.05). Systolic shortening of the left ventricular transverse diameter declined from 41 to 36% (p less than 0.01), though in no instance did it fall below the lower limit of normality (30%). After 8 weeks of betablocking therapy, blood pressure and heart rate remained essentially unchanged. Systolic shortening increased slightly but insignificantly to 38%. The left ventricular enddiastolic diameter did not change throughout the study. It is concluded that longterm betablocking therapy is associated with a significant reduction of left ventricular function which improves in the later stage of treatment. Since the diminution of left ventricular function is slight, the induction of left heart decompensation is unlikely, at any rate in patients with initially normal left ventricular function.

Adrenergic beta-Antagonists↗

[Pancreatogenic ascites].

Pancreatic ascites is a rare disease which is often misinterpreted as ascites secondary to alcoholic cirrhosis or to intraabdominal cancer. It can be diagnosed by a high protein and amylase/lipase content of the ascitic fluid. If diagnosis and subsequent surgery occur at an early stage, the prognosis is good. The natural course, therapy, prognosis, and pathogenesis of pancreatic ascites are discussed on the basis of experience with 7 patients.

Adolescent↗