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Biomedical subjects

N R Paleev

Publications and source records attributed to N R Paleev.

At least 55 records · Page 3Linked to original sources
PubMed1994

[Individual patient sensitivity to glucocorticoids and hormone resistance in bronchial asthma].

The paper reports glucocorticoid actions in bronchial asthma, covers problems of individual sensitivity to glucocorticoids and resistance to hormones, illustrates the dependence of beclometasone dipropionate efficacy on condition of glucocorticoid receptors in alveolar macrophages and clinical appearance of the disease, describes physiological features of patients with hormone-resistant bronchial asthma and its new treatment (extracorporeal photohemotherapy) allowing reduction of prednisolone dose in 14 of 15 patients from 29.6 to 11.4 mg/day, on the average.

Adult↗
PubMed1994

[Hemodynamics and anaerobic glycolysis during the head-down tilt test in myocarditis patients].

The analysis is presented of the changes observed in hemodynamics and anaerobic metabolism in myocarditis patients given increasing preload. It is shown that the antiorthostatic test can specify substantial deposition of blood in the lesser or greater circulation. Patients with congestive cardiac insufficiency demonstrate more frequently increased lactate levels in the blood of the coronary sinus and reduced myocardial extraction of lactate.

Adolescent↗
PubMed1994

[Effect of transcutaneous stimulation of diaphragm on systemic and central hemodynamics in patients with chronic bronchitis].

25 males and 5 females suffering from chronic obstructive bronchitis (COB) underwent transcutaneous diaphragmatic electrostimulation (TDE). As shown by central intrapulmonary hemodynamics, those patients who had no circulatory decompensation benefited from TDE. There was a decrease in the pulmonary hypertension, intensification of general hemodynamics, reduced tonicity of the pulmonary arteriolar bed, improvement of right ventricular function. In circulatory decompensation TDE may cause deterioration of right ventricular function, enhancement of circulation decompensation against unchanged pulmonary hypertension and pulmonary-arteriolar tonicity. The changes in pulmonary artery pressure, total pulmonary vascular resistance, pulmonary-arteriolar elasticity observed after a single TDE session may prompt the validity of further COB treatment according to the above regimen.

Adolescent↗
PubMed1993

[The efficacy of the extracorporeal ultraviolet irradiation of autologous blood in the treatment of chronic nonspecific lung diseases].

The paper presents the results of treating patients with chronic nonspecific diseases of the lung by the use of extracorporeal ultraviolet autoblood irradiation (EUVABI). The marked clinical effect recorded after an EUVABI course coincided with the normalization of an erythrocytic membrane morphoform, which suggests that the severity of allergic and inflammatory reactions was liquidated and blood viscosity was improved. EUVABI led to positive changes in the pattern of morphotypes in the crystallogram of plasma, except the patients who showed no clinical effect, which indicates that plasma crystallography can be used as a diagnostic test in predicting the results of EUVABI application.

Adult↗
PubMed1993

[Changes in the blood rheological properties in the transcutaneous irradiation of the ulnar vascular fascicle with a helium-neon laser].

An investigation of blood rheologic properties in 12 patients with acute pneumonia has been made by using low-energy He-Ne laser (LG-79-2) irradiation of vascular fascicle. 37 exposures have been performed, 40 min each. Immediate effects of He-Ne laser were studied comparing blood samples taken before and after the radiation. Results obtained have demonstrated transcutaneous blood irradiation causing prompt and pronounced effects on blood rheologic characteristics: reduced blood viscosity, improved both viscous-elastic properties and osmotic resistance of erythrocytes, activated platelet aggregation. These effects excluding the latter are rather positive for the human body. As for platelet aggregation, its activation following transcutaneous laser irradiation of blood might be expected to grow into a factor of risk provoking pathologic thrombogenesis in venous congestion, hypercoagulation and vascular wall injury.

Acute Disease↗
PubMed1991

[Myocardium in chronic obstructive lung diseases].

The analysis of endomyocardial biopsies (10 specimens) and clinical observations suggests the conclusion: myocardial lesions in OPD patients with pulmonary hypertension are due to metabolic and hemodynamic disturbances. In addition to myocardial hypertrophy, myocardial dystrophy contributes to development of cor pulmonale.

Biopsy↗
PubMed1991

[Ultraviolet irradiation of the blood in the treatment of pyo-inflammatory complications in patients with terminal renal failure].

The authors describe a technique of extracorporeal UV radiation of blood (EUVRB) in flow closed circulation. Its efficacy was assessed in combined treatment of pyo-inflammatory complications of terminal renal failure. Therapeutic effects of EUVRB are due to reduced endogenic intoxication, correction of leukopoiesis and stimulation of immunity. The changes in laboratory findings correlated with clinical pattern of the inflammation. EUVRB produced a favourable response and improved therapeutic results of pyo-inflammation treatment in patients with terminal renal failure.

Adolescent↗
PubMed1991

[Cardiogenic shock in dilated cardiomyopathy].

The present communication is based on an examination of 33 cases with dilated cardiomyopathy and 48 with severe myocarditis. Nine patients with dilated cardiomyopathy were diagnosed as having developed cardiogenic shock. Clinical examination, echocardiography, right heart and pulmonary artery probing were performed. Cardiogenic shock in dilated cardiomyopathy was demonstrated to be characterized by a progressive decrease in cardiac contractility, no increase in peripheral vascular resistance, and high pulmonary hypertension. Profound cardiomyocyte alterations followed by increased fibrosis of intermuscular and perivascular spaces contribute to the development of cardiogenic shock in dilated cardiomyopathy.

Adult↗
PubMed1990

[Mechanisms of lesions of myocardial contractility in infectious-allergic myocarditis].

Clinical and morphologic analysis of 63 biopsy specimens and of 23 autopsy specimens has shown the leading role of immune inflammation with the development of delayed and immediate type hypersensitivity in injury to myocardial contractility. It is the immune inflammation that is responsible for disorders in electrolyte metabolism, microcirculation, sympathetic nervous system reactivity.

Autopsy↗