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Biomedical subjects

N R Paleev

Publications and source records attributed to N R Paleev.

At least 37 records · Page 2Linked to original sources

[Integrative study of bronchial asthma in perimenopausal women].

The paper presents results of complex study of the specific features of the course of bronchial asthma (BA) in the peri- and early postmenopausal periods, including investigations of hormonal and immunological statuses, bone tissue mineral density and blood lipids, and evaluates the effects of peri- and early postmenopause and climacteric syndrome of varying severities on the course of BA. A drug test using estrogens has been developed to evaluate their effects on bronchial airflow. It has been shown that estrogens do not negatively affect bronchial airflow in most patients with BA in the peri- and early postmenopausal periods. The efficiency of replacement hormone therapy with estrogen-progestogen drugs has been for the first time estimated in these patients. Treatment with the estrogen-progestogen drug clinonorm increases the effects of endogenous cortisol, which makes it possible to reduce a dosage of glucocorticosteroids and to increase the mineral density of bone tissue.

Adult↗

[Does "pulmogenic hypertension" exist?].

Validity of criteria of so called "pulmogenic hypertension" in chronic obstructive pulmonary diseases was assessed with the use of a questionnaire and simultaneous 24 hour monitoring of blood pressure and peak expiratory rate in 80 and 28 patients, respectively. This method of bifunctional monitoring allowed to study relationship between blood pressure level and degree of bronchial obstruction. The results did not confirm the presence of "pulmogenic hypertension" as a special form of arterial hypertension.

Adult↗

[Treatment of arterial hypertension in patients with bronchial asthma].

Treatment of arterial hypertension in patients with concurrent chronic obstructive diseases of the lungs has limits in prescription of antihypertensive drugs. STAMLO--long-acting calcium antagonist--is proposed for monotherapy of mild and moderate hypertension in patients with bronchial asthma. The drug decreases hypertension in the greater and lesser circulation, improves bronchial permeability.

Adult↗

[Problems of psychosomatics and somatopsychiatrics in internal medicine].

The past 2 decades in our country has been marked by the population's poorer health status, the obvious tendency for the incidence of many somatic and mental diseases to increase. The problem of somatogenic mental diseases and disorders diagnosed in the presence of a somatic disease merits particular attention. The paper considers the background of psychosomatics and somatopsychiatrics, presents the authors' own findings of the mental status in patients with chronic lung diseases. Various somatic disease-detected psychopathological syndrome relationships most common in the treatment of visceral diseases are systematized. Emphasis is laid to the fact that the differentiation of proper mental and somatic diseases, the elaboration of the optimal treatment policy is possible only if therapeutists work in close cooperation with psychiatrists. Principles in the complex therapy of psychopathological disorders in patients with somatic diseases are given.

Humans↗

[Ventricular late potentials and ventricular arrhythmias in noncoronarogenic myocardial diseases].

Hemodynamic parameters and survival were studied in 48 patients with noncoronarogenic myocardial diseases (NCMD). The examination included high-resolution electrocardiography and Holter monitoring of cardiac rhythm. Deterioration of pump capacity of the heart was associated with high-grade arrhythmias (4B and higher) while ventricular late potentials were more characteristic for patients with severe hemodynamic disorders and, in particular, with dilated cardiomyopathy. The prognosis in NCMD is based on clinical evidence on functional class of the heart failure, parameters of central and intrapulmonary hemodynamics.

Adolescent↗