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Biomedical subjects

N Moriyama

Publications and source records attributed to N Moriyama.

At least 253 records · Page 14Linked to original sources
PubMed1986

[Synchronously diagnosed and treated triple cancer (rectum-ureter-prostate)].

A 63-year-old man was admitted for examination of a rectal tumor. A stony hard nodule was palpated in his swollen prostate by rectal examination. The biopsies proved rectal and prostate carcinoma. Transabdominal echogram and DIP showed left hydronephrosis. Left ureteral cancer was suggested by the typical "goblet sign" with retrograde ureterography. Rectal lower anterior resection, left total nephroureterectomy with partial cystectomy, castration and pelvic lymphadenectomy were undertaken synchronously. The pathohistological diagnosis was triple cancer consisting of rectal mucotubular adenocarcinoma, prostatic carcinoma and ureteral transitional cell carcinoma. The diagnosis and treatment of the triple cancer were discussed.

Adenocarcinoma↗
PubMed1985

Vascular invasion as a prognosticator of metastatic disease in nonseminomatous germ cell tumors of the testis. Importance in "surveillance only" protocols.

Forty-five nonseminomatous germ cell carcinomas of the testis were evaluated retrospectively to define the biologic features associated with the occurrence of metastatic disease. A statistical analysis of several pertinent clinical and pathologic factors was performed. The factors evaluated included: duration of symptoms before diagnosis, serum level of alpha-fetoprotein, serum or urinary level of human chorionic gonadotropin, testicular weight, extent of local tumor (pathologic T stage), and vascular invasion at the primary site. In each case, metastases were documented by a retroperitoneal node dissection, other biopsies, or by chest films. In 29 tumors with vascular invasion, 25 patients were seen with metastatic disease. In 16 tumors without vascular invasion, 3 patients demonstrated metastasis. The presence or absence of vascular invasion was strongly correlated with concomitant lymph node involvement or subsequent appearance of other metastatic disease (chi-square = 17.19). Additionally, vascular invasion in bifactoral++ analysis with tumor size and pathologic T stage proved a significant prognosticator even in low-staged (chi-square = 8.48) and small tumors (chi-square = 8.13). The implications of these findings, both as an adjunct to the staging of nonseminomatous germ cell tumors and in the management of clinical Stage I lesions, are discussed.

Adolescent↗
PubMed1985

Inverted papilloma: observation with scanning and transmission electron microscopy.

Three cases of inverted papilloma of the urinary bladder were studied by transmission electron microscopy. Scanning electron microscopic observation was made in one of these. The surfaces of the outer-most tumour cells were covered with short stubby microvilli. Multiple bud like proliferations of the tumour cells were compatible with a trabecular type of inverted papilloma. The tumour cells of the trabeculum mimicked the intermediate and basal cells of the epithelium which covered the surface. Microcysts are believed to be formed by epithelial migration into pits, creating an epithelial inversion, and do not represent central necrosis. Ultrastructure suggests that inverted papilloma is a very well differentiated tumour.

Adult↗
PubMed1985

Large spontaneous intrahepatic arterioportal fistula demonstrated by rapid sequential computed tomographic scan. Report of two cases.

A huge spontaneous intrahepatic arterioportal shunt with regurgitation through the portal vein trunk was demonstrated by computed tomography and confirmed by angiography in 2 patients with liver cirrhosis. Rapid sequential computed tomographic scanning was very useful in the diagnosis and follow-up after arterial embolization. Early visualization of the portal vein and increased attenuation in the ipsilateral lobe bearing the fistula were demonstrated in 1 case, and the same findings were also demonstrated by computed tomography and angiography in the other case.

Adult↗
PubMed1985

Preoperative imaging of liver metastases. Comparison of angiography, CT scan, and ultrasonography.

Thirty-one patients with mostly colorectal cancer metastases to the liver had preoperative selective/superselective angiograms (24 cases), computed tomography (CT) [26 cases, mostly enhanced by contrast administered by a peripheral vein (9), the common hepatic artery (9), or the portal vein (5)], and ultrasonography (26 cases). Intraoperative ultrasonography and palpation and examination of the resected specimens revealed 113 tumors. CT detected almost half of the masses smaller than 1 cm, and ultrasonography and angiography about one-third of lesions 1-2 cm in size. Ultrasonography was less powerful for examination of the posterior segment of the liver. CT and ultrasonography placed the tumors into subsegments more accurately than did angiography. Almost 40% of the preoperative plans had to be changed: in two-thirds by extended resections and in one-third by a change from curative to palliative intent. Most changes were due to extrahepatic tumor growth, often within areas screened before surgery. The use of all three imaging modalities for liver metastases is recommended for preoperative planning.

Angiography↗
PubMed1985

Intrahepatic portal vein branches studied by percutaneous transhepatic portography.

Percutaneous transhepatic portography was performed in 31 patients. Based on the anterior and lateral images, the authors have concluded that the portal vascular system described in most anatomy textbooks does not correspond to the anterior portogram. A more practical nomenclature and order of branches are proposed, in which the first order includes the proximal portal vein branches; the second order includes the right anterior and posterior segmental branches, the umbilical portion of the left lobe, and most of the caudate veins; and the third order includes the peripheral (subsegmental) branches. The liver is divided accordingly into three main segments and one secondary segment (the caudate lobe), with each of the main segments being divided into two subsegments. The authors suggest that this new nomenclature will be helpful in both diagnosis and surgery.

Adult↗
PubMed1985

Intrahepatic venous collaterals forming via the inferior right hepatic vein in 3 patients with obstruction of the inferior vena cava.

When the inferior vena cava is obstructed, collateral veins enlarge, connecting with the inferior (accessory) right hepatic vein (IRHV) and thence through various hepatic veins to the right atrium. Three such cases are described. In one patient, most contrast material flowed into the IRHV and from there to the left hepatic vein. The second patient had several large collaterals arising from the IRHV and flowing into the right and middle hepatic veins, while the third patient demonstrated anastomoses between the IRHV and the middle hepatic vein. All of these hepatic venous shunts eventually drained into the right atrium. There were no clinical manifestations such as ascites, edema, or dilatation of the abdominal veins. Cavography alone or combined with computed tomography proved to be diagnostic in the assessment of these intrahepatic collaterals.

Collateral Circulation↗
PubMed1985

Bile duct necrosis: complication of transcatheter hepatic arterial embolization.

Bile duct necrosis because of transcatheter hepatic arterial embolization (THAE) in two patients with hepatocellular carcinoma is reported. Preoperative THAE was performed on 29 patients, and bile duct necrosis was experienced by two of the 29 (7%). In these two patients, gelatin (Gelfoam) powder was used as the embolus. Among the 24 whose embolus was clear, four were embolized with gelatin powder. Therefore, incidence of bile duct necrosis after THAE with gelatin powder was 50%. Because of the hazards of severe complications such as bile duct necrosis, we conclude that gelatin powder should not be used except for the THAE of no more than one segment of the liver.

Bile Ducts↗
PubMed1985

Gallbladder infarction after hepatic artery embolization.

Nineteen patients with hepatocellular carcinoma had transcatheter hepatic arterial embolization and subsequent hepatic resection with cholecystectomy. During the angiographic procedure, inadvertent embolization of the cystic artery occurred in 10 patients (53%). Subsequent histologic study of the gallbladder demonstrated necrotizing ulcerative cholecystitis in nine of the 10. All nine patients complained of right-upper-quadrant pain of varying degree after hepatic embolization, but none required special treatment or urgent laparotomy.

Aged↗
PubMed1985

A case of diffuse type of combined hepatocellular and cholangiocellular carcinoma initially presented as a localized small nodule.

A combined hepatocellular and cholangiocellular carcinoma of diffuse type in a Japanese man is described. A small localized solitary tumor apparently grew rapidly into a diffuse-type carcinoma, and the liver weight increased about 4-fold during the last two months. The clinical course of this case was as expected for a diffuse type of hepatocellular carcinoma except that unusually high levels of serum carcinoembryonic antigen were found. The patient died of hepatic failure with systemic bleeding five months later. At autopsy, multiple small nodules were suspected to be intrahepatic metastatic foci because portal tumor thrombus was observed in the right antero-superior segment where the initial tumor was localized. Histologically, the tumor had components of both hepatocellular and mucin-producing cholangiocellular carcinoma. This is believed to be the first report on a diffuse type of combined hepatocellular and cholangiocellular carcinoma initially presented as a localized small nodule.

Adenoma, Bile Duct↗
PubMed1984

Loss of epidermal growth factor receptor on the renal neoplasm induced in vivo with Xenotropic pseudotype Kirsten murine sarcoma virus.

A characteristic feature of normal rat kidney (NRK) cells in their ability to bind epidermal growth factor (EGF) and loss of the ability to bind EGF in the renal neoplasm induced in vivo with C type RNA virus were demonstrated. Maximal binding capacity and apparent dissociation constant of NRK cells were 3.36 femtomoles of EGF bound per 10(6) cells and 2.85 X 10(-11) M, respectively. The binding of EGF to transformed cell in vivo with Xenotropic pseudotype Kirsten murine sarcoma virus was abolished.

Animals↗