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Biomedical subjects

N Miyazaki

Publications and source records attributed to N Miyazaki.

At least 127 records · Page 7Linked to original sources
PubMed1986

[Report of cases of adenomatoid tumors of the epididymis].

This is a report of two cases of adenomatoid tumor on the epididymis. Both patients presented with the chief complaint of an intrascrotal mass. One patient, 56 years old, had a tumor on the left epididymis and underwent left epididymectomy. The other patient, 65 years old, had a tumor on the right epididymis and underwent resection of the tumor. Subsequently histological diagnosis confirmed an adenomatoid tumor. From the Japanese literature, 103 cases of adenomatoid tumor including the present cases were reviewed. The tumor was located on the epididymis in 83 cases with a mean age of 39.6 years and on the testicular tunica in 11 cases with a mean age of 27.5 years. These tumors originated from two sites, from the serosal lining of the genital tract and from the Müllerian remnant. The former type is called by Yasuma the Mesotherial type and the latter, the adenomatoid type. The present two cases are of the adenomatoid type, which is usually found on the tail of the epididymis in men from 30 to 50 years of age.

Aged↗
PubMed1985

Diffuse peripheral lung disease: evaluation by high-resolution computed tomography.

High-resolution computed tomography (HRCT) was performed on 15 patients who had diffuse peripheral lung disease, and the findings were compared with those of conventional chest radiography and histologic examination. Bullae, interstitial fibrosis with honeycombing, and small granulomas were more clearly and specifically demonstrated on HRCT scans than on conventional chest radiographs in all patients. Histologically proved mild alveolar wall thickening due to alveolitis in cases of sarcoidosis and systemic lupus erythematosus was not detected. HRCT is useful for performing detailed morphological analyses of abnormalities of the peripheral portions of the lung.

Adult↗
PubMed1985

Serum concentration and effects of a single dose of enalapril maleate in patients with essential hypertension.

The antihypertensive effect of a non-sulfhydryl, long acting ACE (angiotensin converting enzyme) inhibitor, MK-421, was evaluated by administering a single dose of 10 mg to 13 patients with mild to moderate essential hypertension. The pharmacokinetic profile of MK-421 and its potent active metabolite, MK-422, was also assessed, together with the effect on the various components of the renin-angiotensin system. A single dose of MK-421 produced a significant fall in MBP from 2 to 24 hours post-drug. As could be expected, plasma ACE activity was suppressed up to 24 hours after MK-421. The half-life of MK-422, Cmax and [AUC]24(0) of MK-421 and MK-422 were measured. No significant change in plasma bradykinin or urinary excretion rate of kallikrein was observed, whereas a slight increase was observed in the urinary excretion rate of kinins after MK-421 in 8 patients. Significant correlations were observed between pretreatment PRA levels and the maximum fall in MBP.

Adult↗
PubMed1984

[Penetration of cefmenoxime into pleural fluid].

Single doses of cefmenoxime (CMX), 1 g intravenous drip infusion, were administrated to 5 patients with pleural effusion. The study group consisted of 3 men and 2 women, aged 38 to 69 years (mean 54.8 years); 4 had carcinoma with pleural effusion and 1 had SLE. Pleural fluid and serum samples were taken at intervals 1 to 24 hours for determination of CMX levels. The following results were obtained: Intravenous drip infusion of 1 g CMX yielded a peak pleural concentration of 4.5 micrograms/ml after 2 hours and pleural levels over 3 micrograms/ml were maintained for 5.5 hours after intravenous drip administration. Ratio maximum pleural concentration to peak serum level reached 15.0 +/- 8.3% at 2 hours after intravenous drip administration.

Adult↗
PubMed1984

[Adrenal cyst: report of a case].

This is a case report of an adrenal cyst which developed in a 36-year-old man. The patient experienced sudden abdominal pain, accompanied by sweating. The diagnosis was established by ultrasound-sonography and CT-scan. The adrenal cyst was removed surgically; it measured 20 X 10 X 10 cm and contained 1,900 ml of a white, cloudy fluid. Histological examination showed that the cyst wall was lined with mesothelial cells and was of congenital origin. The cyst was endocrinologically non-functioning, for all the endocrinological data were within normal limits. After surgery, however, hypertension has persisted and has been diagnosed as being essential in origin. This is the 63rd case reported in the Japanese literature.

Adrenal Gland Diseases↗