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Biomedical subjects

N Masurel

Publications and source records attributed to N Masurel.

At least 127 records · Page 7Linked to original sources
PubMed1972

Field trial with human and equine influenza vaccines in children: protection and antibody titres.

A placebo-controlled influenza vaccination trial was carried out on 374 children in the winter of 1967-68. The children were randomly vaccinated with 300 CCA of A2/England/1/1966, 300 CCA of A/equine 2/Miami/1963, or with a placebo. During this winter an influenza outbreak occurred, caused by A2/Nederland/1968. The A2 vaccine yielded a protection rate of 58% (P = 0.02) and the A/equine 2 vaccine a rate of 19% (P = 0.33). Serological data revealed that all influenza infections occurred in subjects who had a pre-epidemic haemagglutination inhibition titre below 150. The antibody response against various human influenza A2 viruses and against the horse strain (A/equine 2) is discussed.

Animals↗
PubMed1969

Serological characteristics of a "new" serotype of influenza A virus: the Hong Kong strain.

Serological studies in the Netherlands have shown that exposure to A2 influenza viruses during the period 1957-67 increased the level of haemagglutination-inhibiting (HI) antibody against A/Equi-2 virus in the sera of persons aged 60 years or more and against A2/Hong Kong/68 virus in sera from persons less than 60 years old. On the other hand, HI antibody titres against A/Swine/30, A/PR/8/34 and A1/Nederland/49 viruses were not reinforced by exposure to A2 viruses.From these and other findings, the author concludes that the influenza virus strains of the A/Swine era are distantly related antigenically to those of the A2 era, that the pandemic virus of 1889 most closely resembles that of the 1957 pandemic, and that the Hong Kong-type virus appeared in man about 1900 and is probably responsible for A/Equi-2 antibodies found in human sera.

Antibodies↗