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Biomedical subjects

N M Shevchenko

Publications and source records attributed to N M Shevchenko.

At least 19 recordsLinked to original sources
PubMed1991

[Use of a Soviet-made device for recording late ventricular potentials].

Late ventricular potentials (LVP) were detected with an ECG signal-averaging installation developed at the Institute of Radio Engineering and Electronics, USSR Academy of Sciences. A total of 103 patients were examined: 33 with sustained ventricular tachycardia (VT), 30 with unsustained VT and high-grade ventricular premature contraction, 20 with coronary heart disease, postinfarction cardiosclerosis without arrhythmias and 20 apparently healthy subjects (controls). LVPs are the most susceptible to sustained VT in the presence of postinfarction cardiosclerosis (77%), their specificity is lower (70%). LVPs are a low sensitive marker (35%) for sustained idiopathic VT. In unsustained VT and high-grade premature ventricular contraction, LVPs were recorded infrequently in 1 (3%) of the 30 patients.

Action Potentials↗
PubMed1991

[Possibilities of the combined use of transesophageal electrostimulation of the heart and physical load in the diagnosis of paroxysmal reciprocal atrioventricular tachycardia].

Possibilities of using transesophageal electrostimulation of the heart in combination with a physical load were studied in 38 patients with paroxysms of reciprocal atrioventricular (AV) tachycardia. The study has shown that the physical load exerts a pronounced influence on the induction, persistence, and electrophysiological parameters of AV tachycardia, significantly increases the functional capacity of the anterograde conduction along the anomalous tract, and reduces the efficacy of vagal techniques in alleviating paroxysms of AV tachycardia.

Adult↗
PubMed1990

[The potentials for curing atrial flutter by the combined use of transesophageal electrical stimulation and anti-arrhythmia preparations].

Potentialities of the recovery of the sinus rhythm were studied in 21 patients with atrial flutter (AF) using frequent transesophageal electric cardiac pacing (TEEP) per se and after intravenous injection of ritmilen and novocainamide under outpatient conditions. TEEP made it possible to arrest AF in 24% of patients and to transform flutter into steady atrial fibrillation in 48% of patients. In 28% of cases, the pacing turned out ineffective. Subsequent administration of antiarrhythmic drugs made the rhythm return to normal in 24% of patients, whereas repeated TEEP conducted after drug administration in additionally 33% of patients. The efficacy of frequent TEEP combined with administration of ritmilen and novocainamide amounted to 81%.

Adult↗
PubMed1989

[The therapeutic efficacy of a gonococcal vaccine].

The therapeutic efficacies of 2 gonococcal vaccines are compared. One of them is made from gonococcal strains selected for their antigenic characteristics, the other is a commercial vaccine prepared from a random sample of gonococcal strains. The studies have demonstrated a higher therapeutic efficacy of the former vaccine. This fact calls for the creation at production centers of permanent collections of antigenically full-value gonococcal cultures; such collections will help improve the gonococcal vaccine, standardize it, and enhance its biological activity.

Anti-Bacterial Agents↗
PubMed1989

[Use of digoxin in patients with paroxysmal supraventricular tachycardia].

The effectiveness and electrophysiologic mechanisms of antiarrhythmic effect of digoxin were examined in 27 patients with paroxysmal atrioventricular nodal reciprocal tachycardia (PAVNRT) and supraventricular tachycardia (SVT) due to latent complementary conductive pathways, i. e. latent Wolff-Parkinson-White (WPW) syndrome. To assess antiarrhythmic action of digoxin, transesophageal pacing and plasma digoxin radioimmonoassays were used. Preventive antiarrhythmic efficiency of digoxin was 53% in PAVNRT patients, and 25% in SVT patients with latent WPW syndrome. Antegrade atrioventricular conduction block seems to be the mechanism of oral digoxin preventive effect. There was no relationship between antiarrhythmic efficiency of digoxin and its plasma level.

Action Potentials↗
PubMed1989

[The clinical importance of atrial fibrillation-flutter induced by electric transesophageal stimulation of the heart].

A study was made of the clinical importance of atrial fibrillation-flutter (AFF) induced by using different modes of left atrium stimulation via the esophagus. Ninety-eight patients were entered into the study including 40 patients with a history of AFF paroxysms, 24 with risk factors of AFF development, and 27 practically normal persons. The stimulation modes applied permitted reproducing stable paroxysms of AFF in 85 percent of the patients with a history of arrhythmias and in none of the normal persons. As for the patients with risk factors, stable paroxysms of AFF could be induced in 33 percent of the cases. The specificity and sensitivity of transesophageal electrophysiologic stimulation (TEES) with the modes applied were 100 and 82 percent, respectively. The investigations have demonstrated that TEES appeared most effective when applied in the mode of an even increase of the frequency of the set pace up to 300 imp/min.

Adolescent↗
PubMed1989

[Sinoatrial reciprocal paroxysmal tachycardia].

Detection rates and features of the clinical course of paroxysmal reciprocal sinoatrial tachycardia were examined in 34 patients. The features of the tachycardia should include its short-term and less marked clinical manifestations. In tachycardia, mean heart rate was 118 +/- 13 per minute. Long-term ECG monitoring was found to be the most adequate tool for the diagnosis of paroxysmal sinoatrial tachycardia. The potentials of transesophageal electrostimulation of the heart in the diagnosis and assessment of the clinical significance of that tachycardia were demonstrated to be limited due to instability of induced paroxysms.

Adult↗