[Judgement of therapy results achieved in case of carcinomas (author's transl].
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Adult↗
Biomedical subjects
N Leipner
Publications and source records attributed to N Leipner.
[Carcinomas of the Nasopharynx. Clinical aspects--treatment results--therapeutical improvements (author's transl)].
In the years from 1968-1977 to 44 out of 63 patients with carcinomas of the nasopharynx and to 15 out of 19 patients with malignant lymphomas of the nasopharynx curative radiation therapy was applied. The survival-rates for all carcinomas amount to 63,2% after 3 years, and to 46,5% after 5 years. Half of the patients live up to only 9% of their mean, age- and sex-dependent life expectancy. The prognosis differs with the histological type. Patients with transitional-cell-carcinomas had the smallest chance of survival; half of them did not survive. 0.08% of their age-dependent life expectancy. Skeletal infiltration and metastases of the cervical lymph nodes have a bad influence on the therapeutic results. Local recurrences developed in 20% of the patients. Using the examples of 3 patients, who don't belong to the analyzed collective, we shall discuss and optimize the radiotherapeutic management. As a result it is found out, that the megavoltage irradiation therapy (42 MeV X-rays) makes a better dose distribution in tumour-volume than cobalt 60 rays.
Aged↗
[Problems of evaluation of therapy results achieved in tumor patients (author's transl)].
The success of a therapy can be judged in a more objective manner by comparing the survival times of a group of patients with those of comparable sound persons. In order to complete the histological classification of the different tumor types, the criteria "characterizing survival time T" and "a" can be established by adapting the survival times to the scheme of Weibull.
Adult↗
[Radiation therapy of the nasopharyngeal carcinoma: results of treatment and criteria of optimization (author's transl)].
From 1968 till 1977, out of 84 patients with a malignoma of the nasopharynx 44 underwent sole radiation therapy with curative doses because of histologically established nasopharyngeal carcinoma. The 3-year survival rates for all the carcinomas amount to 63.2%, 5-year survival to 46.5%. Prognoses differ according to the histological type of carcinoma, but therapeutic results are also influenced by osseous involvement or by spread to the lymph nodes. Local recurrences appeared in 20% at the base of the skull, at the pharyngeal roof or in the region of the posterior nasal apertures. Following analysis of the patient collective a critical examination of imaginable and of practically used irradiation schedules is performed. Of the possible arrangements for radiation therapy those with readily reproducible parallel opposed field adjustments using ultrahard photon beams are to be preferred.
Adolescent↗