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Biomedical subjects

N Leipner

Publications and source records attributed to N Leipner.

At least 37 records · Page 2Linked to original sources
PubMed1987

[Liver metastases of colorectal carcinoma: computerized tomographic follow-ups and prognoses in relation to therapy].

Liver metastases of colorectal carcinomas were diagnosed by computed tomography in 116 patients. Several control examinations were made during the course of the disease. The therapeutic effect on the metastases is defined by measurements of the tissular density. Patients submitted to dearterialization or local chemotherapy showed a higher incidence of regressive tumor calcifications and necroses than untreated patients ans patients treated by systemic chemotherapy. The median survival of the untreated patients is 3.6 months, patients treated by systemic chemotherapy have a median survival of 7.9 months, and patients submitted to dearterialization and local chemotherapy show a median survival of 15.7 months. Patients treated by resection survived 36 months, which is about 10 months longer than the survival of patients treated by dearterialization, considering comparable metastatic stages. An increased survival after systemic chemotherapy was only observed in patients of stage 1.

Adult↗
PubMed1987

[Computed tomography and MR tomography before and after radiotherapy of primary and secondary CNS lymphoma].

CT scans were made prior to and following radiotherapy in eleven patients with primary or secondary malignant lymphomas of the CNS. Six patients were additionally submitted to MR tomography with calculated T1 and T2 images. Radiotherapy induced a very rapid regression of the lymphomas. A measurable quantitative influence of the irradiation could thus not be visualized in the MR scans. The survival curve of our patients was calculated, too. The median survival after radiotherapy is 17.4 months.

Adult↗
PubMed1986

[DSA and conventional angiography compared in the angiographic diagnosis of impotence].

Twenty-three patients complaining of impotence were examined angiographically as part of their investigation. In all patients, DSA as well as conventional angiography was carried out. The purpose of this investigation was to compare the two methods with regard to their diagnostic value. By means of sequential analysis it was shown that, with an error level of 10%, DSA was superior to conventional angiography.

Adolescent↗
PubMed1986

[Dynamic cavernosography. Radiologic diagnosis of venous induced erection disorders and erectile body diseases].

In 30 to 50% erectile dysfunctions are due to vascular disorders. Roughly a third of these vasculogenic disturbances is based on venous disorders. These venous-induced erectile failures may be objectivated and radiologically located via dynamic cavernosography, combined with a simultaneous recording of a cavernous pressure profile. Based on over 130 examinations it was possible to provide both an exact description of the normal venous drainage in normal potent men and to give a good idea of the different venous leakages in patients complaining of erectile dysfunctions. Congenital and acquired penile deviations along with Peyronie's disease may also be appropriate for dynamic cavernosography.

Adolescent↗
PubMed1985

[Plasma cell granuloma of the lung].

Plasma cell granuloma is a rare, benign and usually solitary round tumour of the lung. Although uncommon, it is found relatively more frequently among children and adolescents. The lack of symptoms and absence of characteristic features make diagnosis difficult. In adults, the differentiation from bronchial carcinomas is particularly difficult because of their radiological similarity. Consequently, thoracotomy and excision of the tumour is the treatment of choice.

Aged↗
PubMed1985

[Cavography in the digital subtraction technic].

Experience with 74 patients has shown that digital subtraction angiography is a suitable method for the demonstration of the vena cava. In 28 patients the examination was repeated by the conventional large film angiography procedure, but this added no significant information to help to solve the clinical problem. Electronic contrast enhancement permits lower concentrations of contrast to be used than for conventional techniques. Combined with a more selective use of films, this leads to a reduction in the cost of the examination.

Humans↗
PubMed1985

[Scintigraphy in the diagnosis of intestinal hemorrhage].

13 patients with gastrointestinal hemorrhage underwent a scintigraphic examination to localize the bleeding. In 6 patients Tc-99m labeled red blood cells, in 7 patients Tc-99m sulfur colloid were used. Scintigraphy could demonstrate an intestinal bleeding in ten patients, in whom the conventional examinations, and among them 7 abdominal angiographies had failed. 5 of them had to be operated after that, whereby the scintigraphic findings were verified. One of the three patients with negative scintigraphy had to undergo an operation because of continuous bleeding. The methods of scintigraphy and their indication in gastrointestinal hemorrhage are discussed.

Adult↗
PubMed1984

[Portal perfusion following Warren shunt].

Report on 15 controlled patients with open Warren-Shunt. The pre- and postoperative percentage of portal liver perfusion was determined by the sequential liver perfusion scintigraphy. The portal liver perfusion was significantly reduced after Warren-Shunt, presumably because the perfusion of the spleen is derived from portal perfusion. The preoperative size of the spleen may be correlated to the reduction of portal perfusion. Therefore, spleen perfusion and its percentage of portal perfusion should be measured preoperatively.

Adult↗
PubMed1984

[Asbestosis. Computed tomography in comparison with conventional roentgen diagnosis].

Thirty patients (27 men and 3 women) with an average industrial asbestos exposure of 19 years have been examined. The results of conventional radiography and CT have been analysed and compared with pulmonary function studies. The advantages of CT depend on a better demonstration of the pleura and lung periphery. In 24% of cases plaques were diagnosed by chest x-rays which could, however, be excluded by computed tomography. Correct prediction of restricted ventilation was possible in 84% patients by means of CT. On the other hand, this prediction by means of conventional radiographs could be made reliably only if there was extensive fibrosis.

Adult↗
PubMed1984

[Comparison of intra-arterial digital subtraction angiography with conventional arteriography].

Conventional arteriography and intra-arterial DSA were compared in 243 individuals for examination of the liver, kidney, lower extremity and portal vein. There was no significant difference in the diagnostic value of these methods. DSA suffers from a poorer spatial resolution in the periphery of vessels, but this has not resulted in a loss of clinically relevant information.

Analog-Digital Conversion↗
PubMed1983

[Malignant mesenchymal liver tumors in the computed tomogram].

The computer tomographic appearances of very rare sarcomas of the liver have been demonstrated in five cases (four haemangiosarcomas, one spindle-cell sarcoma). On the plain scan, all the tumours appeared less dense than the liver parenchyma, but in haemangiosarcomas there was a marked increase in density after the infection of contrast up to an isodense level. During angio-CT, densities equal to intrahepatic vessels were observed. There was only a slight increase in density of the spindle cell sarcoma after contrast injection. The CT appearances have been compared with the pathological and anatomical structure of the tumour.

Adult↗
PubMed1982

[Angiomatous dysplasia (Weber type) (author's transl)].

A rare form of angiomatous dysplasia with hypotrophy of the left arm is described. Numerous haemodynamically significant arterio-venous fistulae could be demonstrated in the soft tissues and in bone. The venous and lymphatic systems were normal. The lacunar reticular-cystic changes in the spongiosa of the phalanges are pathognomonic of arterial angiodysplasia of the Weber type. In most cases this is associated with bone hypertrophy.

Adolescent↗
PubMed1982

[Thymomas--clinico-pathologic aspects].

A collective of 38 patients with a thymoma, confirmed by microscopic investigation, was analysed retrospectively. 63% of them were female. In 27% of the cases the final diagnosis could be made by autopsy only. 56% of the operated patients lived half of their age-dependant expectation of life. The 5- and 10-year-survival rates amount 84% and 68%, respectively. Of the non-operated patients no one was alive 2.5 years after diagnosis. There was no consistent relationship between the different histologic structure of thymomas (degree of lymphocytic infiltration) and the clinical behaviour and the survival rate. All patients with "parathymic syndromes" were women. One case with pure red cell anemia (erythrophthisis) was associated with spindle-shaped epithelial thymoma. The incidence of myasthenia gravis did not depend on the histologic pattern of thymomas.

Adolescent↗