The disposition of cytotoxic agents after intralymphatic infusion.
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Biomedical subjects
Publications and source records attributed to N D Reis.
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A 28-year-old man presented with a clinical picture suggestive of complex regional pain syndrome type I following a blow to the thenar eminence and thumb. Symptoms, including swelling of the hand and distal forearm, progressed until an amputation was carried out to rid the patient of an unendurable painful and nonfunctioning wrist and hand. The histologic evaluation of the amputation specimen showed: 1) dermal edema, perivascular dermatitis, and epidermal hyperkeratosis; 2) subcutaneous chronic inflammation with subtotal replacement of the adipose lobules by fibrous tissue associated with thickening of the muscular fascia, implying the fasciitis-panniculitis reaction pattern; 3) atrophy, degeneration, necrosis, and focal calcifications of the skeletal muscles; 4) phlebosclerosis, phlebectasias and lymphocytic arteritis; and 5) increased cortical porosity of the bones. It seems that the pathogenetic process underlying the fasciitis-panniculitis syndrome may rarely manifest as a complex regional pain syndrome-like disorder.
A review of the literature revealed that voluntary habitual dislocation of the hip in children is a rare entity. We encountered the case of a 6-year-old girl with habitual posterior subluxation of the hip. Parental counseling is all that was needed while spontaneous resolution of the condition was awaited.
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A 55-year-old woman had a dislocation of a total hip arthroplasty that could not be reduced by closed manipulation because of an obstructing cement fragment. The use of percutaneous arthroscopic instrumentation allowed reduction by successful manipulation of the fragment out of the joint.
A rare case is described of giant swelling of the soft tissue around the knee joint. A large popliteal cyst was present, the fleshy walls of which penetrated the muscle layers of the calf. The place of arthrography in diagnosis is stressed. The yellow-brown mass was confirmed histologically to be pigmented villonodular synovitis. The mechanism of formation of a popliteal cyst is discussed. The differential diagnosis and treatment are reviewed briefly: our preference is for radical surgery.