Biomedical subjects
N Begg
Publications and source records attributed to N Begg.
Child health computing.
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Role of epidemiology in vaccine policy.
The application of epidemiological techniques is important at all stages in the development of a vaccination programme. Before licensing, the safety and efficacy of a new vaccine must be determined in carefully designed clinical trials. An epidemiological assessment of the disease is then needed in order to formulate an appropriate strategy for delivery of the vaccine. Once the vaccine has been introduced into routine use, continued evaluation, both of the vaccine and the programme, is required. Surveillance schemes should be established that are capable of detecting changes in vaccine safety and efficacy as well as monitoring coverage in the target population. Any important changes should be further evaluated by special studies. Postlicensing evaluation of vaccines and vaccination programmes has played an important role in shaping policy in the UK.
Rubella vaccination policy: a note of reassurance.
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Rubella vaccination: the effect of health education and administrative systems on vaccination rates in two health authorities.
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Large outbreaks of Clostridium perfringens food poisoning associated with the consumption of boiled salmon.
Five large outbreaks of food poisoning are described in which clinical, epidemiological or laboratory data indicated Clostridium perfringens as the causative organism. The foodstuff common to all incidents was boiled salmon served cold as an hors d 'oeuvre. In all cases the fish had been subject to a long period of cooling or storage between boiling and consumption. It is thought that multiplication of the organism occurred during this time. Recommendations are made for the avoidance of further similar incidents.
Mycobacterium chelonei associated with a hospital hydrotherapy pool.
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