[Anatomy and physiology of the prostate gland].
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Biomedical subjects
Publications and source records attributed to M Zerbib.
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In order to more clearly define the risk of infection of prostatic biopsy, the authors conducted an analysis of the morbidity of each method. The risk of infection, the possible forms of prophylaxis and the best indications are presented for each method.
One case of intra-abdominal seminoma with persistent müllerian duct syndrome is reported. Literature is reviewed and guidelines for management of such are suggested.
An improved technic for exposure of urethrovesicovaginal fistula during operation by a low approach involves placing the patient in ventral decubitus with the thighs abducted and the buttocks separated. Successful results have been obtained in 7 of the 10 patients operated upon during the last two years. One of the 3 patients treated unsuccessfully had recovery surgery with a positive outcome, the 2 others presenting pronounced breaking down of urethra.
In order to define the prognosis of pure squamous carcinomas of the bladder, on the one hand (group I), and the possible aggravating role of the presence of squamous tissue in an invasive renal cell tumour, on the other hand (group II), 46 cases files of patients treated between 1975 and 1984 were analysed retrospectively. Group I consisted of 18 cases of pure squamous carcinoma (11 men with a mean age of 71 years and 7 women with a mean age of 74 years). 66% of cases presented with haematuria, but urinary cytology was of little help. The diagnosis was established by transurethral resection with 18 grade 3 tumours: stage A in 4 cases and stage B in 14 cases. 10 patients had unilateral (8 cases) or bilateral (2 cases) complications of the upper urinary tract. The presence of lymph node and/or haematogenous metastases was investigated by bone scan, hepatic ultrasonography, pulmonary tomography and, most importantly, by bipedal lymphography combined with percutaneous cyto-aspiration of suspicious nodes. 4 patients presented with invasion of the obturator lymph nodes (2 cases) and iliac lymph nodes (2 cases). 9 patients were treated by total cysto-prostatectomy, 6 patients by radiotherapy (60 Grays) and 3 patients did not receive any treatment. The overall survival was 12.5% after 2 years. None of the patients treated by radiotherapy were alive after 2 years. 29% of the patients treated by surgery survived for 2 years, but none of them were alive after 5 years, essentially as a result of local recurrence.(ABSTRACT TRUNCATED AT 250 WORDS)
In order to assess the potential benefits of radical cystectomy in bladder cancer associated with pelvic lymph node metastasis, a retrospective study compared 2 groups of patients with T2-T3 N+ bladder cancer: 10 treated by radical cystectomy and 14 treated conservatively once the diagnosis of nodal metastasis had been established by fine needle node aspiration or lymphadenectomy. The survival rates were identical in both groups: 80% of the patients died within 2 years, 60% during the first year after diagnosis, mainly due to distant metastasis. No patient in the conservative arm required salvage cystectomy because of local progression. It is concluded that radical cystectomy is of little benefit in T2-T3 N+ bladder cancer, a disease which is no longer amenable to purely local treatment.
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Several teams over recent years have proposed deep transurethral incision of the prostate as treatment for obstructive symptoms secondary to primary bladder neck sclerosis or to a small prostatic adenoma. We have performed this technique in 16 patients over a period of 9 months: 9 cases of primary bladder neck sclerosis and 7 prostatic adenomas weighing less than 20 grams. There were no post-operative complications. This technique was definitely effective on the dysuria with 93% good results at 6 months. The preservation of post-operative anterograde ejaculation was less certain; 27% of our patients developed post-operative retrograde ejaculation. The indication for TUI amongst the other available surgical techniques depends on a rigorous pre-operative assessment evaluating the size and the nature of the obstruction. It is a remarkably simple technique which effectively cures the dysuria. It also markedly decreases the risk of retrograde ejaculation. As this complication is difficult to predict, the patients should be informed of the risks prior to the operation.
The prone position is often used in urologic surgery: posterior approach for pyeloureteral procedures, repair of vesicovaginal fistulas... Positioning of the patient and intraoperative ventilation are facilitated by use of an antistatic, fitted mattress.
This report adds three cases to those previously published of paradoxical reactions to benzodiazepines. The clinical syndrome, more or less complete, is fairly stereotyped, with behavioural disorders, tendency to feelings of hostility and aggressiveness and total anterograde amnesia. Personal and environmental factors seem to play a prominent role in its development. The classical contra-indication of benzodiazepines following such reactions is discussed, and the hypothesis that mamillary-thalamic benzodiazepine receptors play a part in their genesis is envisaged.
Ultrasonography was used to evaluate the patency of portocaval shunts in 9 patients: 2 with spleno-renal anastomosis, 4 with portocaval truncular anastomosis, 2 with mesenteric-caval shunt and 1 with atypical shunt. The shunt count be demonstrated in 7 of these 9 patients. Angiography was performed in 6 cases and confirmed the results of ultrasonography--a finding favourable to the latter method and in agreement with those of other authors. However, the usefulness of ultrasonography varies according to the type of shunt created, as shown by our own experience and by published reports: 70% of portocaval truncular shunts, 65% of spleno-renal shunts and 46% of mesenteric-caval shunts are demonstrable by ultrasounds, these variations being due to differences in location and accessibility to the ultrasonic examination. It ultrasonography fails to display the anastomosis, it may provide indirect signs of patency. In addition to being harmless and relatively inexpensive, ultrasonography is a valuable method for evaluating portocaval shunts. It can easily be repeated and its results need not be confirmed by angiography.
Complicated pyelo-ureteral duplication in the adult may be revealed by recurrent pyelonephritis or urinary leakage. The diagnosis can be performed by combined urography and ultrasound scan. The management is rarely conservative. In most cases, it consists in hemonephrectomy. The ureterectomy is partial, extending up to the pelvic brim in the case of a fine ureter. If the ureter is dilated, however, the ureterectomy must be subtotal, in order to avoid postoperative infectious recurrence.
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15 patients with primary hyperparathyroidism were studied by Thallium scintigraphy in order to localize, preoperatively, the parathyroid adenoma(s). Compared with the operative findings, the scintigrams provided correct information in 10 cases and false information in 5 cases. These results are therefore inferior to those previously reported in the literature.
Ureteral stricture occurring after radio surgical treatment of uterine cervix cancer does not necessarily express a recurrence of malignancy. The same radiological features may be seen after radiotherapy and then has an incomparably better prognosis. Having in mind the natural history of cancer of cervix we analysed 28 cases of such a tumor, treatment by radiotherapy and surgery. This study led us to defend several discriminating criteria between these 2 conditions. A diagnostic strategy is suggested.