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Biomedical subjects

M Zaviacic

Publications and source records attributed to M Zaviacic.

At least 55 records · Page 3Linked to original sources
PubMed1986

Argyrophil and argentaffin APUD cells in the human female prostate homologue and urethra.

In the female prostate homologue and urethra, numerous argyrophil and rare argentaffin cells were found. Grimelius method displayed the closed and open types of argyrophil cells in all cases this study. The findings indicate the possibility of endo/para/crine activity of the female prostate homologue and urethra and support the opinion on the non-vestigial role of the prostate homologue in woman.

APUD Cells↗
PubMed1985

The adult human female prostata homologue and the male prostate gland: a comparative enzyme-histochemical study.

Selected conventional and special histochemical methods were used to investigate the distribution and activity of 7 hydrolytic enzymes and 8 oxidoreductases in paraurethral glands and ducts, the female prostate and the male prostate. Comparative histochemical study revealed a corresponding distribution and also a virtually consonant activity of the same enzymes in the glands of the male and female prostate. In either group of the enzymes examined there was not a single case that an enzyme characteristically present in the glandular cells of the acini of the male prostate would be absent in the structure of the female prostatic tissue, so far referred to as "vestigial" or "rudimentary". The observed corresponding enzymic equipment of the male and female prostatic tissue may provide the basis for the "histochemical concept of male and female prostate homology", which could suitably supplement the present only embryologically understood homology between the paraurethral glands and ducts so as to consider them the female prostate and the male prostate.

Adolescent↗
PubMed1985

The adult human female urethra. Enzyme-histochemical study.

In the female urethra, the activity and distribution of 15 enzymes was determined by using both conventional and special histochemical methods. The enzymatic equipment differed according to the type of epithelial lining whose variation is characteristic for the female urethra. In the stratified squamous epithelium of the urethra, alkaline phosphatase, beta-glucuronidase, acetyl-beta-D-glucosaminidase, thiamine pyrophosphatase, and glucose-6-phosphatase exhibited but minimal or no activity, yet the other 10 enzymes studied displayed activity particularly in basally situated cells. Nearer to the lumen of the urethra, the activity in the epithelium kept decreasing and was mostly absent in superficial and desquamated cells. In the pseudostratified columnar and in the transitional epithelium of the urethra, the majority of enzymes showed an evenly distributed activity at all epithelial levels. In the apical parts of the most superficially situated cells bounding the lumen of the urethra, a distinct narrow zone of higher activity was observed. It was seen not only on determining the majority of dehydrogenases but also on examining acid phosphatase and naphthyl esterase. The endocrine cells occurring in the uroepithelial lining of the female urethra displayed, yet always with the exception of squamous epithelium (Zaviacic et al. 1983), distinct activity of acid hydrolytic enzymes, and of the enzymes studied it was particularly acid phosphatase. The majority of the demonstrated enzymes, of the dehydrogenases priority, is to be given to succinate dehydrogenase, enabled to differentiate readily between the highly active striated muscle fibers located in the most peripheral parts of the excisions along the urethral circumference and the smooth musculature of the urethral wall with a lower or only minimal activity.

Acetylglucosaminidase↗
PubMed1984

Rhythmic changes of human female uroepithelial squamous cells during menstrual cycle. Transmission and scanning electron microscopic study.

The cellular component of the fluid of female urethral expulsions was analysed in two healthy women (37-year-old multipara and 27-year-old nullipara) on days 1, 10, 12, 14, 26 and 27 of their menstrual cycle. Transmission and scanning electron microscopy were used to determine standard values of uroepithelial squamous cells of the fluid of female urethral expulsions on different days of the menstrual cycle. In agreement with the known changes of these cells found in cytological smears during the cycle, electron microscopy confirmed characteristic changes in the appearance of the fine cell structure and the space configuration of the squamous cells. Changes in the desmosomal junctions among squamous cells during the cycle were found. Striking adherence of bacteria and mucosubstances to the squamous cell surfaces were observed in the first half of the menstrual cycle and at the time of ovulation.

Adult↗
PubMed1984

Circatrigintan (30 +/- 5 d) variations of the cellular component of female urethral expulsion fluid. A biometrical study.

Data on the amount of uroepithelial squamous cells released into the fluid of urethral expulsions were obtained in a 37-year-old multipara by daily five consecutive repeated applications of the digital stimulation technique, carried out over the period of one and a half of her menstrual cycle. During the secretory phase of the cycle the rate of the cellular component was far higher than during the proliferative phase. These quantitative biometrically analysed data provide a complementary picture to the qualitative cytological changes of uroepithelial squamous cells occurring during the menstrual cycle that have been reported so far.

Adult↗