[A case of idiopathic throbocytopenic purpura associated with hyperthyroidism (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Yasuda.
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Hand plates with preaxial polydactyly from 13 human embryos of the Carnegie stages 17-23 were examined macro- and microscopically. Morphological features in early pathogenesis of preaxial polydactyly are (1) an abnormal extension and a delayed involution of the apical ectodermal ridge on the preaxial border of the hand plate in stages 17 and 18, (2) a precocious development of an interdigital notch between the duplicated thumbs in stages 17 and 18, and (3) bifurcation of the distal part of the first digital ray in stage 19. A disorder of the interaction between limb ectoderm and mesoderm is considered to be the pathogenetic event.
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