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Biomedical subjects

M Wysocki

Publications and source records attributed to M Wysocki.

At least 145 records · Page 8Linked to original sources
PubMed1983

Successful pregnancy following surgery for a masculinizing adrenocortical carcinoma.

A 16-year-old girl with a masculinizing adrenal carcinoma treated surgically is presented. Following surgery a full clinical and steroid remission has been achieved, without any adjuvant chemotherapy. In the 7th year after the surgical treatment the patient became pregnant. Pregnancy and labour were uncomplicated. The patient continues in complete remission, and her son has been noted to have normal development at 21 mth of age.

Adolescent↗
PubMed1983

[Interdependence between hormonal disorders, stage of development and degree of malignancy of prostatic cancer. 1].

The aim of this study was to determine whether in human clinical practice destruction of the prostate gland by a malignant process is accompanied by a fall in serum testosterone and dihydrotestosterone levels. Mean serum testosterone and dihydrotestosterone levels were significantly lower and LH levels notably higher in patients with metastases than in those without metastases. No notable differences were found between serum testosterone and dihydrotestosterone levels in relation to the degree of malignancy of the tumours. Concentrations of relatively inactive androgens (DHA and delta-4-androstenedione) in the serum were normal. The fall in serum concentration levels with later increase in LH levels is probably caused by malignant destruction of the prostate gland.

Acid Phosphatase↗
PubMed1982

The role of computed tomography in the localization of adrenal cortex tumors.

The aim of this study was to evaluate the usefulness of computed tomography in the localisation of adrenal tumors producing aldosterone and cortisol. One case each of Conn's and Cushing's syndrome are described. The diagnosis of Conn's syndrome was established by demonstrating an elevated plasma aldosterone level "at rest" and its decrease after stimulation, the absence of plasma renin activity and a lowered plasma potassium level. The diagnosis of Cushing's syndrome due to adrenal adenoma was established by demonstrating the typical clinical features, an abnormal diurnal rhythm of cortisol and ACTH secretion and an increased urine excretion of 17-OHCS without suppression by large doses of dexamethasone. The localisation and the size of the tumors as determined by computed tomography were confirmed during surgery.

Adenoma↗