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Biomedical subjects

M Weninger

Publications and source records attributed to M Weninger.

At least 91 records · Page 5Linked to original sources
PubMed1980

Childhood obesity: serum lipoproteins, glucose and insulin concentrations after an oral glucose load.

In 15 grossly obese children (10 boys, 5 girls, age: 13,1 +/- 2,4 years, mean overweight 71 +/- 13%) an oral glucose load (45 g/m2) was performed. Blood glucose was determined by means of hexokinase method and serum insulin was estimated by radioimmunoassay. According to the criteria of Rosenbloom our results show, that 5 out of the 15 children must be considered to have abnormal glucose tolerance tests. In comparison to reference values basal serum insulin values were slightly elevated, the corespondending concentrations after the oral glucose load were markedly increased in all children. Furthermore, serum lipoprotein determinations were performed using the Lipid-Research-Clinics-Method, NIH, Bethesda: Comparing the mean LDL-cholesterol and HDL-cholesterol concentrations with those of age and sex matched controls no statistical differences could be found. However, the HDL-cholesterol values showed a tendency towards lower concentrations. Our data suggest that disturbances of carbohydrate metabolism in grossly obese children could be only detected after the performance of an oral glucose tolerance test.

Adolescent↗
PubMed1980

[Reliability of statistical methods in anthropology].

Univariate and multivariate statistical methods are confronted as to their efficiency and objectivity. Similar to the comparison of patients showing chromosomal aberrations or serious diseases with their normal controls, the investigation of various populations can only result in the determination of differences on the basis of features arbitrarily selected, but not in a classification of systematic categories. Objections as to the objectivity of statistical procedures in the field of racial classification are discussed.

Anthropology↗
PubMed1979

As to the influence of climate on head form.

In two quite different geographical regions--Moçambique and Hierro (an island of the Canaries)--observations have been made which point to an influence of climatic conditions on head dimensions: In localities of higher altitude or/and with colder climate maximum head breadth, minimum frontal breadth and auricular height proved to show higher dimensions compared with localities of milder (more hot) climate.

Angola↗
PubMed1976

[Dermatoglyphics of homo- and heterozygotes for Wilson's disease (hepatolenticular degeneration) (author's transl)].

Dermatoglyphics of 11 patients with Wilson's disease and 16 of their clinically asymptomatic relatives of first degree were investigated; 11 of the latter ones were heterozygous in agreement with the turn over rates of Cu-67, 12 under the assumption of autosomal recessive inheritance. On the finger tips the Mb. Wilson patients showed 52.7% whorls, their heterozygous relatives about 40%; compared with our controls (males 33.16%, females 28.82%, Aue-Hauser, 1970) that means a strong increase of this pattern type. On the palm the high frequency of hypothenar patterns in homo- and heterozygotes for Wilson's disease and of loops with accessory triradius in the 4th interdigitum of the patients with Wilson's disease was striking.

Dermatoglyphics↗
PubMed1975

[Dermatoglyphic investigations in respect to the genetic basis of autoimmune diseases (author's transl)].

Dermatoglyphics of patients with systemic lupus erythematosus, scleroderma and Sjögren's syndrome were very different from the striking findings in Hashimoto's thyroiditis established in 1971 (Weninger and coworkers). Hence, it was concluded that the characteristic dermatoglyphic pattern of Hashimoto's thyroiditis is specific for this autoimmune disease, but not the expression of a general genetic predisposition to autoimmunity.

Autoimmune Diseases↗
PubMed1975

[Dermatoglyphics and creases in a family with brachydactyly (type Drinkwater I) to the question of the relation between dematoglyphics and four-finger-crease (author's transl)].

Dermatoglyphics and creases of three persons (grandmother, mother, son) with brachydactyly (type Drinkwater I) were examined. The finger prints showed only arches and loops of very low quantitative value. On the palm the increased frequency of a high ending of line D, of thenar patterns as well as the general tendency to form an ulnar loop on the hypothenar region were striking. All the three persons had a classical transverse crease (four-finger-crease) on both hands. The relation between dermatoglyphics and transverse crease is discussed from the aspect of the etiology of the four-finger-crease.

Dermatoglyphics↗
PubMed1975

[Chromosomal instability in homo- and heterocygocity for microcephalia vera )author's transl)].

In a family with microcephalia vera, not only the 3 microcephalic probands, but also their healthy mother showed a significantly increased rate of spontaneous structural chromosomal aberrations in cultures of lymphocytes of the peripheral blood. Thus an increased aberration rate in the lymphocytes of asymptomatic family members could serve as a sign of heterocygocity. The qualitative analysis revealed aberrations of the chromatid and chromosomal type; exchanges that are frequently found in Fanconi's and Bloom's syndrome could not be detected. Therefore it can be assumed that the chromosomal instability of microcephalia vera is caused by a specific mechanism.

Adult↗