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Biomedical subjects

M Weiner

Publications and source records attributed to M Weiner.

At least 217 records · Page 12Linked to original sources
PubMed1975

Corynebacterium aquaticum septicemia. Characterization of the microorganisms.

An 85-year-old woman with the diagnosis of diabetic ketoacidosis developed septicemia during hospitalization. Cultures of the patient's blood revealed the presence of Gram-variable coccobacilli, later identified as Corynebacterium aquaticum. The microorganisms grew aerobically on blood agar plates after incubation overnight. The colonies were convex, non-hemolytic and slightly yellow-pigmented. No growth was observed on MacConkey and endo agar plates. The organisms were catalase-positive, oxidase-negative, motile, and oxidized glucose and mannitol. The morphologic and biochemical properties of Corynebacterium aquaticum should be considered for separation from related organisms such as Listeria monocytogenes, Corynebacterium species and oxidative Gram-negative rods that do not grow on MacConkey medium (Flavobacterium spp.).

Aged↗
PubMed1975

A computer-assisted instruction course in the diagnosis and treatment of respiratory diseases.

A computer-assisted simulation of the 'chart method' of teaching has been developed and was used to provide instruction in clinical decision-making in the diagonosis and treatment of pulmonary diseases. The course requires a student to reach and to defend a diagonisis and to provide appropriate treatment for each of 10 simulated cases. Evaluation of performance and immediate feedback and correction of errors of commission and ommission are an integral part of the course. The course provides a model for development of additional programs in other subject areas.

Curriculum↗
PubMed1975

The objective and timing of drug disposition studies, appendix I. Species differences in the tissue distribution of metazimid, an imidazolone derivative.

A marked species difference has been observed in the tissue distribution of metazimid in the rat vs the dog after repeated doses. Differences in toxicity between these species are consistent with tissue levels but not plasma levels. No species differences in patterns of drug metabolism could be found in association with the marked difference in tissue cumulation.

Animals↗
PubMed1975

The objective and timing of drug disposition studies, appendix IV. Phenylbutazone formulations: in vitro dissolution and in vivo performance.

Human plasma level studies were conducted on various phenylbutazone formulations. The resultant data indicated that the nature of the formulation had a marked influence on the rate of phenylbutazone absorption. An in vitro dissolution rate apparatus was employed in an attempt to predict potential absorption of phenylbutazone from a given formulation. Based upon the in vitro-in vivo correlation, a new phenylbutazone tablet product was developed which produced a complete and more rapid absorption of the drug.

Adult↗