[Apparently primary cervical adenopathies. Evaluation and curative treatment apropos of 28 cases].
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Biomedical subjects
Publications and source records attributed to M Wayoff.
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Associated with nasal secretion, the ciliary activity establish the first line of defense of respiratory mucosa. The primary pathology of the ciliary structures is not well known. Correlated with testing of the mucociliary transport, only the ultrastructural study could open this very interesting field. With a short review of the present status of the ineffective mucociliary clearance mechanisms, 9 new cases of immotile cilia syndrome, with or without situs inversus, are studied. Actually, the following anomalies seems to be significant : lack of one or two dyneïn arms, confusion of the central doublets' axis, ciliary roots anomalies. Despite that more information is needed, a good knowledge of this genetic errors is henceforth necessary for clinical and therapeutical applications especially to avoid undue surgical treatments.
The more frequent practise of X-ray examination shows that symphalangism may be involved by other synostosis. Maroteaux described in 1972 "multiplex synostosis disease". Seven personal cases (all female) in two families are described with particular problem of deafness and vertebral fusion. Dominant autosomic inheritance.
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The authors propose a method for the investigation of the muco-ciliary function of the nasal mucosa: they record the motion of radioactive particles, which are put by sonic nebulisation on nasal mucosa. The average speed is calculated by means of the analysis of sequential images and by the study of the variation of activity in relation to time in several main zones. A half-clearing time of the initial activity is also measured. The average speed is 8.33 mm/minute for normal persons and 2.36 mm/minute for a group of patients. This simple, accurate, non aggressive method is used for pharmacodynamic tests.
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