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Biomedical subjects

M Ward

Publications and source records attributed to M Ward.

At least 325 records · Page 18Linked to original sources
PubMed1976

Ulcerative colitis.

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Colitis, Ulcerative↗
PubMed1976

Barbiturate and anticonvulsant treatment in relation to osteomalacia with haemodialysis and renal transplantation.

Among 39 patients treated by regular haemodialysis for four years or more pathological fractures and histological evidence of osteomalacia were significantly more common in those taking barbiturates. Out of 58 transplant recipients surveyed after one year, seven had osteomalacia; four of these had been taking phenobarbitone and phenytoin and one had taken barbiturates alone. Sedatives and other drugs such as phenobarbitone and phenytoin that induce hepatic microsomal enzymes should probably be avoided when possible in patients with chronic renal failure and after transplantation.

Adult↗
PubMed1976

Susceptibility of Streptococcus mutans to antimicrobial agents.

Fifty strains of Streptococcus mutans, including defined strains and clinical isolates, were tested for susceptibility to 20 different antimicrobial agents. Minimal inhibitory concentrations were determined by a liquid microtiter procedure. Antibiotics that were most effective in concentrations below 0.1 mug/ml included penicillin, ampicillin, erythromycin, cephalothin, and methicillin. Antibiotics effective in concentrations between 0.1 mug and 10 mug/ml included rifampin, lincomycin, thiostrepton, spiromycin, vancomycin, streptolydigan, novobiocin, tetracycline, chloramphenicol, spectinomycin, and gentamicin. Antibiotics effective at higher concentrations ranging from 10 mug/ml to 400 mug/ml included the aminoglycosides kanamycin, neomycin, streptomycin, and kasugamycin. Although most antibiotics exhibited inhibitory effects in a narrow range of concentrations, antibiotics such as tetracycline, thiostrepton, and spiromycin had a 1,000-fold range from the lowest to highest concentrations required for growth inhibition.

Anti-Bacterial Agents↗
PubMed1976

The nitroblue tetrazolium test in Crohn's disease and ulcerative colitis.

In subjects with Crohn's disease and ulcerative colitis, an increased percentage of peripheral blood neutrophils reduces the dye nitroblue tetrazolium. This is probably a non-specific index of inflammatory activity. There is no evidence that defective neutrophil function, as measured by this test, contributes to granuloma formation in Crohn's disease.

Adult↗
PubMed1976

A comparison of short and long haemodialysis.

Two groups of patients treated by short (Milan) and long (Newcastle) haemodialysis were compared for incidence of symptoms and biochemical control. Short dialysis corrected urea and creatinine as well but control of potassium and phosphate were similar. The only apparent penalties to be paid by short dialysis patients were a higher incidence of itching, tingling or numbness, impairment of vibratory sense and difficulty in controlling blood pressure. The short dialysis group had higher haemoglobin and less dyspnoea, muscle weakness and dizziness after dialysis.

Adult↗
PubMed1975

Serum C3 and C4 complement components in ulcerative colitis and Crohn's disease.

Serum C3 and C4 complement components were estimated in patients with Crohn's disease and ulcerative colitis. In Crohn's disease, serum C4 concentrations were significantly higher than those of controls. In ulcerative colitis, significantly higher concentrations of C3 and C4 were associated with severe or extensive disease, and C4 concentrations may remain high, years after total colectomy.

Adult↗
PubMed1974

Frostbite.

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Aircraft↗