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Biomedical subjects

M Wannske

Publications and source records attributed to M Wannske.

At least 19 recordsLinked to original sources
PubMed1995

[Complex hand injuries].

Most problems in the treatment of complex hand injuries result from not clearly recognizing which structures are destroyed or preserved preoperatively. The plan for treatment depends on priorities. Beginning with reduction and osteosynthesis and after suture of tendons, restoring blood supply is most important. Nerve reconstruction is best done soon. But if suture without tension is impossible, secondary nerve grafting is to be preferred. Skin closure is to be done soon if possible. Otherwise we need skin grafts, local or free flaps.

Adult↗
PubMed1988

[Infections of the hand].

Sometimes severe bacterial infections of the hand arise quickly and lead to damage of anatomical structures and loss of function. In this paper pathophysiology and clinical signs are presented. The most important priority in therapy is to prevent the infection from extending to deeper structures in the hand, such as tendon sheaths, and along them to the mid palmar space and Parona's space. The therapy most often indicated is therefore surgical treatment at the very beginning, depending on the severity of pain and swelling.

Abscess↗
PubMed1988

[Intercarpal dislocation in early childhood. A case report].

A case of intercarpal subluxation in a six-year old girl is described. The possibility and danger of open reduction is discussed. The potential complications are loss of bone density and growth arrest as a result of an injury sustained early in life.

Carpal Bones↗
PubMed1985

[Ergotamine-induced disorders of the peripheral blood circulation--a case report].

Ergotism with severe arterial circulatory disorders, sometimes leading to amputation of the leg, is a severe complication following application of drugs containing ergotamine. Often the diagnosis is made by the typical angiographic findings. The history, clinical course and a new treatment in a very severe case is reported.

Adult↗
PubMed1985

[Monomelic melorheostosis of the hand].

Melorheostosis is a rare sclerosing bone dysplasia affecting children and adults. Concerning the etiology it seems to be a metameric abnormality of the tissue of mesodermal origin, which is initiated early in embryonic life prior to the formation of the extremity buds. The flowing hyperostosis is usually associated with limb deformity, soft tissue contractures, severe pain and stiffness of joints. Bone scanning complements standard radiologic studies and permits evaluation of the extent and activity of the disease. Conservative treatment is disappointing. Thus we recommend the excision of the exostoses at an early state to prevent further deformity as is shown in a clinical case report.

Female↗
PubMed1982

[Value of the skin and muscle pedicle in myocutaneous flaps].

The value of a combined skin and muscle pedicle as opposed to the purely muscular pedicle is discussed using the example of the myocutaneous island skin flap of the M. latissimus dorsi in the neck-, shoulder-, and upper arm region. There is an indication scheme for the choice of flap pedicle depending on the tension and kinking of the flap or possible previous damage of the muscle pedicle.

Adult↗
PubMed1979

Early cardiorespiratory prognostic patterns in multiple trauma patients.

Hemodynamic parameters were monitored for one week ( in greatest detail during the first 24 hours) in 50 severely injured people who had been admitted to the hospital for treatment within one hour after the accident and, as judged by the type of injury, had probably lost more than 1 1/2 liters of blood. The estimations included not only blood pressure, heart rate (HR) and shock index but also the cardiac index (CI), pulmonary arterial pressure (PAP), pulmonary capillary pressure (PCP), and parameters of oxygen transport were determined with the aid of Swan-Ganz catheters, CI, SI, and left ventricular stroke work index (LVSWI) were decreased, PAP, total pulmonary resistance (TPR), and total systemic resistance (TSR), were increased from the very beginning in the nonsurviving group, with a high prediction of vital outcome. The Swan-Ganz catheter is valuable in such cases in obtaining early prognostic evaluation and in controlling therapy - ie, volume replacement, vasodilation, and adrenergic therapy.

Adult↗
PubMed1977

[Cardiovascular parameters following severe multiple injuries].

Cardiovascular parameters of 35 patients with multiple injuries are monitored over a period of 7 days. Pulmonary artery pressure, pulmonary vascular resistance, intrapulmonary shunts and cardiac output appear to have a significant prognostic value.

Adolescent↗
PubMed1976

[Release of antibiotics from bone cement and penetration to infected cortical bone (author's transl)].

Addition of antibiotics to bone cement is used more and more in orthopedics and traumatology. Indications are discussed: 1. infection prophylaxis in replacement arthroplasty, 2. therapy and recidive prophylaxis in infected arthroplasty, 3. therapy of chronic osteomyelitis. Our own experiments show release of antibiotics from bone cement Palacos and penetration into cortical bone after experimental osteomyelitis. Carbenicillin and Cephalotin show high level of concentration for 2 weeks, after 3 weeks there is no concentration evident. Lincomycin and Gentamycin in the first days show high tissue levels, after decrease and increase again after second week. Gentamycin was examined during 10 months showing high levels after this time.

Animals↗
PubMed1976

[Antibiotica release from bone cement in animal experiment].

The release of antibiotics from bone cement palacos into cortical bone after experimental ostemyelitis in sheep was demonstrated by our experiments. High carbenicillin and cephalothin concentration levels were present for 2 weeks, but after 3 weeks were no longer evident. Lincomycin and gentamicin in the first days showed high tissue levels, then decreased and increased again after the 2nd week. Gentamicin was examined over 10 months, producing high levels after this time also.

Animals↗