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Biomedical subjects

M Turgut

Publications and source records attributed to M Turgut.

At least 37 records · Page 2Linked to original sources
PubMed2001

The management of carpal tunnel syndrome in pregnancy.

OBJECTIVES: To determine the prevalence of carpal tunnel syndrome (CTS) after delivery and its relationship to individual factors. STUDY DESIGN: A cohort of 46 pregnant women, aged 15-48 years, who had suffered from CTS during pregnancy and who had delivered at Aydin Maternity Hospital, Turkey was selected. They had been followed up through pregnancy and 12 months postpartum and filled out a questionnaire. The data were analysed statistically. RESULTS: Follow up showed that CTS at 6 and 12 months post partum was reported by 10.9% and 4.3% of the women, respectively. The difference in prevalence of CTS between young women and older women was statistically significant (P= 0.005). The history of diabetes mellitus and infant birth weight were similar in the two groups. However, patient weight gain during pregnancy increased the risk of CTS (P= 0.000). On the other hand, there was no difference in the number of previous pregnancies between women with CTS and without CTS during pregnancy (P= 0.210). Furthermore, affected and unaffected groups required Caesarean section in nine and 248 patients during pregnancy, respectively. CONCLUSION: These results indicate that, in most pregnant patients with CTS, the symptoms are present in both hands and are first noted during the third trimester. The majority of patients with CTS obtain spontaneous relief in the immediate postpartum period.

Adolescent↗
PubMed2001

Multifocal extensive spinal tuberculosis (Pott's disease) involving cervical, thoracic and lumbar vertebrae.

An unusual case is reported of a 53-year-old woman presenting with spinal tuberculosis involving cervical, thoracic and lumbar vertebrae. The patient originally presented with progressive quadriparesis, fever, night sweats and weight loss. Imaging studies demonstrated vertebral body destruction with and without paraspinal and/or intraspinal abscess in cervical, thoracic and lumbar regions. The laboratory studies confirmed the diagnosis of Pott's disease and the patient was placed on anti-tuberculosis chemotherapy. The anterior approach was used for removal of the infected necrotic material, bone grafting and instrumentation, in both cervical and thoracic vertebrae. The postoperative course was uneventful and the patient made an excellent neurological recovery. The present report is of the first published case of an extensive spinal tuberculosis involving cervical, thoracic and lumbar spine.

Antitubercular Agents↗
PubMed2001

Long-term neurological outcome of acute encephalitis.

To understand the viral etiology of acute childhood encephalitis in Elaziğ, Eastern Turkey, 36 children aged between 4 months and 14 years who were treated in a regional medical center between January 1995 and June 1999 were studied. Viral etiology was identified in 16 of 34 (47.1 per cent) cases and the most frequently detected pathogens was mumps (seven cases, 20.6 per cent). No specific etiology was found in 18 (52.9 per cent) cases. Among the survivors, mental and/or focal neurological deficits persisted in 18 (52.9 per cent). Two children died and 32 survived, of whom 16 were left with no neurological sequel, 10 had persistent neurological sequel, and eight recovered with some degree of handicap. Improvement in the general health and sanitation of the population, and the universal use and development of new vaccination will significantly reduce the incidence of viral encephalitis.

Acute Disease↗
PubMed2001

In utero MR imaging and management of foetal hydrocephalus and NTDs in the third trimester.

Although ultrasound (US) remains the gold standard in foetal imaging, in utero magnetic resonance (MR) imaging of the foetal nervous system may be useful in the late stages of pregnancy. The authors performed MR scanning in pregnant women in whose foetuses US examination had shown hydrocephalus and neural tube defects (NTDs). These cases are definitely diagnosed as hopeless at such a late stage. In this report, three pregnant patients are presented to illustrate the morphological imaging features, and their outcome is discussed. This report is an example of how radiological investigations can be most valuable, when US and MR imaging are used as complementary in imaging of the foetuses.

Adult↗
PubMed2000

Short term human primary pulpal response after direct pulp capping with fourth-generation dentin adhesives.

The purpose of this study was to evaluate the effects of the total-etch and direct pulp capping techniques on the short-term response of mechanically exposed human primary tooth pulps using three commercially available adhesive resin systems. Class V cavities were prepared on the buccal surface of intact mandibular primary molars and exposed with a carbide bur on the cavity floor. The entire cavity except the exposure site received 36% phosphoric acid gel conditioning. Exposed pulps were capped with one of the three adhesive resins, followed by restoration of the cavities with the respective restorative materials. The teeth were extracted after 60 days and prepared according to normal histological techniques. Serial sections were stained with H/B for histological evaluations. The histopathological evaluation showed that a few of the samples in the Scotchbond Multi Purpose (SMP) and Prime & Bond 2.1 (PB) groups exhibited "attempted bridge formation", while no bridge formation was evident in the other samples. Syntac Single Component (Syntac) exhibited the most severe histological response, while the mildest reactions were observed in the SMIP group. Based on the conditions of the present study, direct pulp capping with dentin bonding agents following the total-etch technique in primary teeth can not be recommended.

Acid Etching, Dental↗
PubMed2000

Spinal cord compression due to multivel thoracic disc herniation: surgical decompression using a "combined" approach. A case report and review of the literature.

A case presenting with signs of spinal cord compression due to double contiguous thoracic disc herniation (TDH) is reported. A 66-year-old woman presented with a 4-month history of intermittent episodes of weakness and numbness in the lower extremities, and urinary dysfunction. Six weeks prior to admission complete paraplegia developed. The diagnosis was established by MRI. Treatment consisted of complete excision of the herniated discs (T8-T9 and T9-T10) and decompression of the spinal cord with a right transpedicular approach combined with standard posterior approach. The postoperative course was uneventful, and the improvement was dramatic. We also include a review of other 39 case reports from the literature. This article highlights the importance of consideration of TDH when one deals with a case with an anterior mass causing spinal cord compression.

Adult↗
PubMed1999

Neurogenic tumors of the mediastinum in children.

Neurogenic tumors of the mediastinum are among the most common mediastinal tumors. They include nerve sheath, autonomic nervous system, and paraganglionic tumors and malignant small cell tumor. Neurogenic tumors arise primarily in the paravertebral sulcus. They are most frequently identified as asymptomatic lesions on routine chest X-rays. The majority of symptoms can be related either to compression of neural elements or other intrathoracic structures or to excess production of biogenic amines. Complete surgical excision performed by a thoracotomy approach offers the best opportunity for cure. In the case of tumors with extension into the spinal canal, a combined thoracic and neurosurgical approach should be performed.

Child, Preschool↗
PubMed1999

The effect of fibrin adhesive (Tisseel) on interbody allograft fusion: an experimental study with cats.

Fibrin glue has been promoted for use in many neuro- and orthopaedic surgical procedures. At present, some surgeons make routine use of the adhesive in augmentation of bone grafting operations. However, there is controversy about its effectiveness in augmenting bone graft healing. This study investigated the use of two-component fibrin sealant (Tisseel, Immuno AG, Vienna, Austria) as an adjunct to graft material in fusion surgery. Twenty-four cats were fused with corticocancellous bone graft, which was taken from a separate cat, across the disc space in the anterior cervical region. In the present experiment, the authors carried out cervical interbody fusions in 24 cats, divided into two groups, to test the usefulness of fibrin glue in fixation of allograft fusions. At surgery, a piece of corticocancellous allograft was placed into the intervertebral disc space at the C5-C6 region, either untreated or locally treated with fibrin adhesive (Tisseel). Fusion mass formation was examined 6 months after the experimental fusion procedure by radiography and computed tomography (CT) scanning and the new bone formed was evaluated histologically. The authors observed that the allograft fusion mass area is more voluminous in the untreated animals in Group I than in the ones augmented with Tisseel, as illustrated by CT measurement (section area and bone density) (p = 0.038). Accordingly, histopathological studies demonstrated a reduced vascularization of the graft as well as diminished new bone formation in the animals treated with Tisseel in Group II. The present investigation demonstrates that local fibrin sealing significantly retards the osteogenic fusion in a model of corticocancellous bone grafting in cats. In view of our results it seems that fibrin sealant is not suitable for fixation of bone fragments in anterior cervical fusion.

Animals↗
PubMed1999

Ulnar to median nerve anastomosis in the palm (Riches-Cannieu anastomosis).

This report describes an unusual case of pure bilateral ulnar innervation of the thenar and hypothenar muscles of the hands. The patient was a healthy 36-year-old woman who presented with neck pain. Examination and routine laboratory investigation findings were normal, but on electroneuromyography ulnar to median nerve anastomosis of the motor fibers in the palm was detected bilaterally. However, there was no anastomosis between the sensory fibers. On investigation of focal neuropathy the anomaly known as Riches-Cannieu anastomosis may surprise the electroneuromyographer and change the clinical signs and symptoms. It should be suspected when the hand muscles are clinically intact in the presence of a severe median nerve lesion in the forearm. In this case, a complete lesion of the median nerve at the forearm might erroneously be interpreted as a partial lesion of the median nerve. In every surgical intervention to the hand, this anomaly should be kept in mind and should be investigated electrophysiologically.

Adult↗
PubMed1999

Spinal angiolipomas: report of a case and review of the cases published since the discovery of the tumour in 1890.

Angiolipomas of the spinal canal are extremely uncommon benign neoplasms composed of mature lipomatous and angiomatous elements. A case of thoracic spinal extradural angiolipoma producing progressive spinal cord compression in a 54-year old housewife is presented and 74 previously reported cases in the world literature over a period spanning nearly one century from 1890 to the present are analysed. The 75 total cases (46 females and 29 males) ranged in age from 6 to 73 years (mean 42.7, SD 15.9; median 43). The angiolipomas were located in the extradural compartment in 72 patients and intradural compartment in 3; 14 of the extradural lesions infiltrated the surrounding bone (infiltrating subgroup). Computed tomography (CT) and magnetic resonance imaging (MRI) revealed the fat-density lesions in all the cases that we studied. The findings indicate that spinal angiolipomas predominantly affect women. Their preponderance in peri- or postmenopausal women, and their fluctuating clinical course during the pregnancy support a role of hormonal influence on the development of the lesion. They often involve the thoracic region, and produce symptoms and signs of spinal compression and, in some cases, bone involvement. MRI is the investigation of choice for the diagnosis of these lesions. Non-infiltrating angiolipomas can usually be removed easily through a laminectomy, but infiltrating angiolipoma can be only partially resected. However, outcome is not worse in the infiltrating than in the non-infiltrating lesions and appears to be relatively independent of the completeness of the surgical removal. Subtotal resection usually provides substantial symptomatic relief, because these lesions are slow growing and do not undergo malignant transformation. The results of this review show that angiolipomas of the spinal canal have a good prognosis after surgical removal, even if infiltrating.

Angiolipoma↗
PubMed1999

Lowe syndrome: case report.

Lowe syndrome is a genetic multi-system disorder affecting the central nervous system, lens and kidney. In this report, constricted palate, multiple eruption cysts and hematomas as the oral findings of a child diagnosed with Lowe syndrome is presented.

Dentigerous Cyst↗
PubMed1998

Sacrococcygeal chordomas: problems in diagnosis and management.

Chordomas are rare, insidious, and slow-growing but locally aggressive, malignant tumors originating from the primitive notochord and localized along the axial skeleton. Between 1988 and 1993, four patients with sacrococcygeal chordomas were treated at the Ankara Numune State Hospital. There was a median 17-month interval between the onset of symptoms and diagnosis. In all patients, a posterior approach was used. In addition, two patients were treated with adjuvant radiation therapy. There were no serious intra- or postoperative complications. Early diagnosis and surgery plus radiation therapy seem to provide the best results in terms of survival.

Adult↗
PubMed1998

Importance of cranial nerve involvement in nasopharyngeal carcinoma. A clinical study comprising 124 cases with special reference to clinical presentation and prognosis.

A review of nasopharyngeal carcinomas (NPCs) treated in the Hacettepe University Hospitals is presented. One hundred twenty-four patients between the ages of 3 years and 72 years were managed in the period 1968-1992. Of these cases, 48 had only cranial nerve (CN) involvement on admission. The most commonly affected CNs were the VIth and the Vth, in that order. The prognostic significance of this finding is obvious, because early diagnosis and treatment is vital in a cancer patient. This study includes retrospective analysis of 124 patients with NPC. The patients were investigated with respect to clinical and radiological diagnosis and outcome. Our results also show that CN involvement in NPC usually requires careful neuro-otological examination. It is suggested that increased knowledge and understanding of the disease among neurosurgeons, neurologists and ENT surgeons would improve the prognosis of patients with NPC.

Adolescent↗