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Biomedical subjects

M Tsuru

Publications and source records attributed to M Tsuru.

At least 127 records · Page 7Linked to original sources

[Computed tomography in the diagnosis of spinal disease (author's transl)].

METHOD: During the period from October 1977 through February 1979, 41 cases of spinal diseases were studied by either EMI Whole Body Scanner, CT 5005 or EMI Head Scanner, CT 1010. Slices were 10 mm or 13 mm thick. MATERIALS: (1) disc diseases 15 cases (2) ossification of posterior longitudinal ligament 10 (3) congenital anomalies 5 (4) spinal cord tumors 6 (5) trauma 3 (6) narrow cervical spinal canal 3 (7) calcification of ligamentum flavum 1 (8) spinal arteriovenous malformation 1. Results obtained are as follows: 1) A precise determination of vertebral level scanned by C.T. is important. 2) Plain spinal C.T. is of diagnostic value in detecting bony lesions and lipoma. Meningioma showed positive images in the enhanced spinal C.T. 3) The spinal cord cannot be distinguished from the surrounding C.S.F. except for that at C1 level. 4) C.T. metrizamide myelography can appraise adjacent structures that may impinge on the spinal subarachnoid space, as well as structures contained in the space.

Adult↗

Purification of acidic Z protein from human liver.

Preparation of Z protein from human liver is described. Z protein consists of 2 forms which have different isoelectric points, pI 5.8 and pI 8.7 respectively. The acidic Z protein has a molecular weight of about 11,000 and has binding affinity for BSP using gel filtration.

Azo Compounds↗

Catheter cervical vertebral venography.

Cervical vertebral venography using catheterzation via the femoral vein was carried out in 78 cases. In disc disease the internal vertebral venous plexus (IVVP) are interrupted at single or multiple levels, and sometimes completely blocked. In ossification of posterior longitudinal ligament, the IVVP are separated bilaterally and interrupted at multiple levels due to centrally situated ossification and associated osteophytes. Venography helps to determine the upper and lower limits of laminectomy, and the necessary sites of facetectomy. The IVVP in the thoracic region were clearly opacified in 86% of 37 normal selective azygograms.

Catheterization↗

[Lateral ventricle tumors (Part 1)--clinical manifestations on 30 cases (author's transl)].

The clinical investigations especially on symptomatology of 30 cases of the tumors of the lateral ventricle are carried out. For the clinical analysis, in agreement with Koos and Laubichler, the tumors of the lateral ventricle are classified into 2 groups, as follows: 1. Intraventricular tumors group (11 cases). 2. Paraventricular tumors group (18 cases). The following points are emphasized in the clinical features excluding radiological findings. 1. Because of symptomatologically no difference between the intraventricular tumors group and paraventricular tumors group, paraventricular tumors are included into the tumors of the lateral ventricle. 2. On neurological signs and symptoms, we contrast "false" localising signs which are common in patients with objective evidence of raised intracranial pressure and intermittent symptoms which occur more frequently with tumors in the ventricular system. 3. The results of surgical removal of the tumors are not always good. The diversity of results probably reflects the grade of malignancy and growth of the tumors, and skillfulness of operative technique is required, not to do damage to essential neurological elements and vital structures neighbouring the lateral ventricle.

Adolescent↗

[Lateral ventricle tumors. (Part 2) -Neuroradiological analyses of 30 cases- (author's transl)].

In the first report, the clinical manifestations of 30 cases of the lateral ventricle tumor were reviewed. This report summarizes neuroradiological findings of the same 30 cases, in which 26 cases were examined by cerebral angiograms and 3 cases by CT scan. For the radiological analyses, the tumors of the lateral ventricle are classified into two groups, as follows: 1. Intraventricular tumors arise in the projection of the choroid plexus, the tela and the ependyma and grow in the lateral ventricle. 2. Paraventricular tumors arise from the wall of the neuroglia not only bulge into ventricle, but in addition infliltrate the substance of the surrounding brain. Following conclusions are obtained. (1) Unilateral hydrocephalus, which is shown clearly by vascular displacements in subependymal veins, is demonstrated in both tumors groups. (2) There are different findings on the feeding arteries, the draining veins and the tumor stains between two tumors groups. (3) In the intraventricular tumors groups, the anterior choroidal artery supplying the tumor is its the plexal segments and atrial segments. (4) On the other hand, the paraventricular tumors group, the anterior choroidal artery supplying the tumor is its the superior penetrating branch to the cerebral parenchyma. (5) Cerebral angiograms can reveal the definite signs of the intraventricular mass, but it is sometimes difficult to evaluate whether its space occupying lesions infiltrates the cerebral substance below the wall of the lateral ventricle, or not. (6) CT scan is useful neuroradiological method in the different diagnosis between two tumor groups, and CT scan provides and anantomical diagnosis rather than a histological one. (7) The accurate diagnosis of the tumors of the lateral ventricle can be demonstrated by both cerebral angiograms and CT scan.

Adolescent↗

Role of the posterior hypothalamus in the development of acute brain swelling.

Destructive stereotaxic lesions were made in the posterior hypothalamus, unilaterally or bilaterally, in 26 dogs. In 21 dogs the intracranial pressure (ICP) was maintained in normal range, and in five dogs the ICP was artificially elevated to 300 to 400 mm h2o, preceding the procedures to the hypothlamus. Arterial oxygen and carbon dioxide pressure ((PaO2 and PaCO2) were maintained in the normal range. Before and after each procedure, systemic arterial pressure (SAP) was elevated by intravenous injection of norepinephrine (5 X 10(-3) mg/kg) to determined whether the ICP increases coincidentally with elevation of the systemic arterial pressure. The intracranial pressure/mean arterial pressure ratio of elevation by injection of norepinephrine was not significant regardless of the level of the ICP, or of uni-or bilateral lesions of the hypothalamus. The authors conclude that dysfunction of posterior hypothalamus does not play a specific role in the development of vasomotor paralysis leading to acute brain swelling, under conditons of normal or moderately raised ICP with normal PaCO2 and Pato2 levels.

Animals↗

[The antero-posterior diameter of the cervical spinal canal in cervical spondylosis. (Part 2) (author's transl)].

1. The antero-posterior diameter (APD) of the cervical spinal canals in 96 cases of cervical spondylosis with radiculopathy and radiculomyelopathy was measured for each vertebra by the method of Burrows, and the thecoperiosteal diameter (TPD) of the cervical spinal canals in the same cases was measured from myelograms by the method of Symon. 2. The APD in patients with myelopathy or positive Queckentedt's test was found to be significantly smaller than those of without them. The upper limit of APD at C4 to C6 vertebrae in patients with myelopathy or positive Queckenstedt's test was 15 mm, while the lower limit of APD in patients with radiculopathy or negative Queckenstedt's test was 13 mm. As based on these findings, the following conclusions were drawn: When the APD is smaller than 15 mm, there is always a chance to develop spondylotic myelopathy or spinal subarachnoid block though not absolute, but if the APD is smaller than 12 mm, the patient will have myelopathy and spinal subarachnoid block absolutely without exception. 3. The TPD in patients with myelopathy or positive Queckenstedt's test was also found to be more significantly smaller than those of without them. It could be seen that the smaller the TPD, the more chance to develop myelopathy and also spinal subarachnoid block. The upper limit of the TPD in myelopathy was 11 mm, and that in spinal arachnoid block was 10 mm. The smallest value in radiculopathy was 9 mm, so that it was suggested that a case which has the value smaller than 8 mm might develop myelopathy. 4. The hight of the inter-body spurs was measured from lateral myelograms in individual case. The value in case with myelopathy and positive Queckenstedt's test was much larger than that of radiculopathy or negative Queckenstedt's test. The lower limit of the hight of the inter-body spurs in case with myelopathy and spinal subarachnoid block was 3 mm.

Cervical Vertebrae↗