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M Tsuru

Publications and source records attributed to M Tsuru.

At least 109 records · Page 6Linked to original sources

[Temporal lobe damage as pitfalls at subtemporal transtentorial approach (author's transl)].

It is essential to make a proper approach to the lesion site and retract brain, thereby securing an adequate field of vision, upon performing operations on patients for lesions of deep temporal lobe and tentorium. Although subtemporal transtentorial approaches to tumors in the tentorium, pyramis and cerebellopontine angle have been described by a number of workers, further studies have to be made on temporal lobe damage as a pitfall since only a few reports have been published to date. We have therefore examined the possible factors which are responsible for temporal lobe damage and brain swelling in six cases in which subtemporal transtentorial approaches were made. We have encountered two cases of meningioma of the pyramis and tentorium growing in the middle and posterior fossa, one case each of acoustic neurinoma and trigeminal neurinoma located in the middle and posterior fossa, one case of aneurysm at a marginal branch of the superior cerebellar artery and one case of arteriovenous malformation of the deep temporal lobe. Temporal lobe damage was observed in two of these cases during operation and in post-operative CT scans. Although no particular symptoms were noted, CT scan revealed temporal lobe damage in one case. One of the main factors responsible for temporal lobe damage is cutting major veins, namely inferior cerebral vein, transverse sinus, etc. However, no damage was resulted from cutting superior petrosal sinus. Intermittent release of the brain retractor and repeated use of hyperosmotic solution including ventricular drainage are recommended for preventing temporal lobe damage.

Adolescent↗

[Middle fossa neurinoma with proptosis and oculomotor palsy (author's transl)].

UNLABELLED: Proptosis and oculomotor palsy which occur with intracranial neurinoma are very rare. CASE: A 29-year-old right-handed female was admitted to the Department of Neurosurgery, Hokkaido University School of Medicine on Sept. 6, 1975. Eight months before admission, the patient complained of double vision and one month later, noticed decreasing of right visual acuity. Four months before admission, right-sided ptosis occurred and she noticed right temporal visual field's defect. Two weeks before admission she became aware of proptosis of right side. On admission, the general examination and vital signs were normal. The neurological examination revealed right optic nerve atrophy, right oculomotor palsy and slight decreasing of right corneal reflex. Radiological examination revealed extracerebral mass lesion in the middle fossa. On Sept. 19, 1975, a right frontotemporal craniotomy was performed and a large dura-covered tumor was found. It was found to extend from the middle fossa to the superior orbital fissure and attached to the anterior wall of the middle fossa. The tumor expanded into the interdual space and tightly attached to the dura mater. Histological examination of the tumor revealed typical neurinoma. Reports on cases with middle fossa neurinoma were reviewed and the origin of the tumor was discussed. It was presumed that the origin of the tumor in this case was the dural branch of the trigeminal nerve in the middle fossa.

Adult↗

Computerized tomography findings in dural arteriovenous malformations. Report of three cases.

Changes in the brain parenchyma and cerebrospinal fluid spaces were demonstrated in three cases of dural arteriovenous malformations by computerized tomography (CT). In various combinations, there were 1) vermiform or patchy enhancement after intravenous contrast infusion, 2) abnormal decreased density mainly in the white matter, 3) local mass effect, 4) hydrocephalus, 5) dilatation of the major venous sinus system, and 6) prominent vascular grooving of the skull inner table. Most of these changes were secondary to raised sinus pressure caused by arteriovenous shunt. It was also demonstrated by serial CT that some elements improved after artificial embolization or surgical excision of the malformations.

Aged↗

[A clinical survey of cerebellar astrocytoma--comparison between childhood and adult cases (author's transl)].

The symptomatological investigations on 20 cases of cerebellar astocytoma were carried out. These cases, observed and treated in Hokkaido University Hospital from 1959 to 1978, were divided into two groups, such as childhood group (under 15 years old) and adult group (over 16 years old). The following conclusions were obtained: (1) The youngest was 2 years old and the oldest was 64 years old. The age distribution showed higher incidence in younger age group under the age of 30, especially in the first decade. (2) The most frequent symptoms were vomiting, headache and unsteady gait in all cases, but vomiting was constantly seen in childhood cases. (3) The average length of history in children was 2.4 months in childhood, and 17.6 months in adult cases. (4) Neurological signs on admission could be summarized as follows. The signs indicating increased intracranial pressure was most frequent, and the next common findings were ataxia of the limbs and trunk. Impairment of the cranial nerves and brainstem were uncommon. On neurological signs there was little difference between in children and in adults. (5) The total cases of complete removal of the tumor were many, but in adults there were not a few cases in which incomplete removal of the tumor was accomplished. (6) The majority of cerebellar astrocytoma were cystic and laterally placed in the cerebellum especially in children. (7) Microscopically in children, the frequent type was pilocytic astrocytoma of juvenile type. (8) The result of surgical removal of cerebellar astrocytoma was excellent, and the long-term survivours were found frequently and the quality of survival was good. The follow-up results in children were better than those in adults.

Adolescent↗

Interference by the 4-hydroxylated metabolite of propranolol with determination of metanephrines by the Pisano method.

Measurements of urinary metanephrines by the Pisano procedure (Clin. Chim. Acta 5: 406, 1960) are unreliable in patients who are taking propranolol owing to the presence of 4-hydroxypropranolol in the urine. Three properties of this propranolol metabolite lead to interference: (a) it is absorbed and eluted from ion-exchange resins under the conditions Pisano used for metanephrine isolation, (b) at high pH it absorbs at 350 to 360 nm, and (c) it is oxidized by periodate to a substance with negligible absorption in this region. Because 350 to 360 nm is the wavelength used to quantitate vanillin, the product formed from periodate oxidation of metanephrines, and because the unoxidized eluate is used as a specimen blank, the presence of 4-hydroxypropranolol spuriously decreases the measured urinary metanephrines; this has special significance because patients being tested for increased metanephrines are also likely to be receiving propranolol for hypertension.

Chromatography, Ion Exchange↗

[A clinical study on postoperative course of cerebellar astrocytoma (author's transl)].

We have made a study on the postoperative course of 20 cases with cerebellar astrocytoma observed and treated in Hokkaido University Hospital from 1957 to 1978. Following conclusions were obtained. (1) Among those 20 patients, 16 were alive at the time of submission. The survival rate was 80% at 5 years respectively and the longest survival period for one of our patients is 19 years postoperatively. (2) Removal of tumor was attemped in all cases and the prognosis was best influenced by the degree of removal. The cases who received a complete extirpation of their tumors resulted in a permanent and complete cure, but the cases of incomplete removal did not give so good results as the cases of complete removal. (3) In the cases who could removed completely, those cases had several factors in common, and from our clinical data, the following factors should be considered. 1. Growth of tumors was circumscribed and tumors did not infiltrate the substance of the brainstem. 2. Tumors arising in the cerebellar hemisphere were found to be more common than those originating in the vermis. 3. It was notable that gross appearance of tumors was high incidence of cystic lesions. 4. Those tumors were a well-differentiated histomorphology and it was found that an overwhelming majority of those astrocytoma were so-called astrocytoma grade I. (4) A particularly benign prognosis was expected when the neoplasm occurred in childhood, but even adult cases if removed completely with several factors mentioned above, demonstrated a good prognosis.

Adolescent↗

[Ligandin].

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Glutathione Transferase↗

[A case of mesenchymal chondrosarcoma originating from the spinal dura (author's transl)].

A rare case of mesenchymal chondrosarcoma originating from the thoracic spinal dura was reported. A 10-year-old girl complained of paresis of the right leg in June 1977. Then she became unable to walk early in August, and a complete paraparesis developed on August 18. She was admitted to our department on August 22. On admission she had complete paraparesis, bilateral ankle clonus, upward plantar reflexes, sensory disturbance below T7, shincter disturbance and neck stiffness. Plain thoracic X-ray revealed bilateral decalcification of pedicles of T6. Myodil myelography showed a complete block between T6 and lower end of T7 vertebrae. Bilateral laminectomy from T3 to T8 was performed. A tumor originating from the spinal dura was located in the right dorsal extradural space. The tumor was totally removed together with a small area of the affected dura. Light microscopy showed mesenchymal chondrosarcoma. Her recovery from neurological deficiencies was excellent and now she can run 14 months after surgery. Metastasis or recurrence has not yet been seen.

Child↗