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Biomedical subjects

M Topilsky

Publications and source records attributed to M Topilsky.

105 records · Page 6Linked to original sources

Coincidence of sarcoidosis and amyloidosis.

Amyloidosis was diagnosed in a patient with sarcoidosis. There was no evidence of any other disease known to be associated with amyloidosis. The joint occurrence of amyloidosis and sarcoidosis appears to be extremely rare, and to our knowledge, this is the second such patient to be reported. Whether the association of the two diseases in this patient represents a causal relationship remains an open question.

Amyloidosis↗

Beclomethasone dipropionate and chronic asthma. The effect of long-term aerosol administration on the hypothalamic-pituitary-adrenal axis after substitution for oral therapy with corticosteroids.

Beclomethasone dipropionate aerosol at a dose of 100 mug four times a day was administered to 32 patients suffering from chronic perennial asthma. Twenty-three of these patients had previously received prolonged treatment with corticosteroids, causing various degrees of adrenal suppression in some patients. Almost complete recovery of adrenal function was observed within a period of six months in most patients. Treatment with beclomethasone dipropionate did not affect the hypothalamic-pituitary-adrenal axis in the other nine asthmatic patients who had not received prolonged corticosteroid therapy previously and who served as a control group.

Administration, Oral↗

Disodium cromoglycate in the treatment of seasonal and perennial rhinitis.

The efficacy of a 2% solution of disodium cromoglycate was evaluated in 15 patients suffering from seasonal rhinitis and 24 patients suffering from perennial rhinitis. DSCG proved to be highly effective in the seasonal group where pollen was demonstrated to be the cause but gave relief only in some atopic patients of the perennial group.

Adolescent↗