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Biomedical subjects

M Tada

Publications and source records attributed to M Tada.

At least 559 records · Page 31Linked to original sources

[Alteration of blood coagulation and fibrinolysis after intra-arterial one-shot chemotherapy in liver cancer].

Twenty liver cancer patients, including 9 hepatocellular carcinoma and 11 with metastatic liver cancer, were treated by intra-arteral one-shot chemotherapy. Alterations in blood coagulation and fibrinolysis were observed serially after one-shot chemotherapy by testing the levels of PT, APTT, FDP, fibrinogen, AT III, alpha 2-macroglobulin, and plasminogen. APTT was prolonged, FDP increased, Fbg increased after a transicent decrease, and AT III, alpha 2-M, and plasminogen decreased. The peaks of these alterations occurred within 7 days after the one-shot treatment; recovery was observed after about weeks. The more advanced the cancer, the greater were the alterations.

Antineoplastic Agents↗

Endoscopic polypectomy for the removal of polyps of the small intestine.

Since intussusception is a common complication of the Peutz-Jeghers polyps, laparotomy should be recommended to remove them. However, all of them will not be palpable or discernible during laparotomy. Operative endoscopy was employed for removing polyps of the small intestine of a 22-year-old female who was previously diagnosed as Peutz-Jeghers syndrome. Using a newly designed enteroscope with two channels (SIF-2C, Olympus), four large polyps over 1 cm in size were removed from the ileum and jejunum with safety. Endoscopic polypectomy is one of the rapidly advancing fields and widely spread methods in gastrointestinal endoscopy since the introduction of electrosurgical techniques. Although the endoscopic removal of polyps arising from the esophagus, stomach, duodenum, colon and rectum can be performed with ease and safety, polypectomy for the polyps of the small intestine has never been performed because of the technical difficulties to handle the scope in the small intestine. Two channel enteroscope resolved this problem. Therefore, it is emphasized that double channel enteroscope makes the polypectomy in the small intestine possible and the indication of enteroscopy will be more extended.

Adult↗

Protective effect of inactivated virus vaccine on Sendai virus infection in rats.

Rats which had received two doses of inactivated Sendai virus vaccine were resistant to intranasal virus challenge. Vaccination was equally effective when administered by intravenous, intraperitoneal, intramuscular, or subcutaneous routes but not the intranasal route. Rats vaccinated intraperitoneally with inactivated Sendai virus vaccine were protected from contact infection. Suckling rats born to vaccinated dams were resistant to challenge infection at 3 weeks of age, but the resistance was not demonstrated after weaning at 4 weeks of age.

Animals↗