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Biomedical subjects

M Swartz

Publications and source records attributed to M Swartz.

95 records · Page 6Linked to original sources
PubMedDate not supplied

Histopathology and ultrastructure of krypton and argon laser lesions in a human retina-choroid.

The authors studied a normal eye 24 hours after retinal treatment with argon and krypton photocoagulation. The findings indicate the relative sparing of the inner retina and greater choroidal effects of krypton when compared with argon photocoagulation. Bruch's membrane was not completely ruptured as long as the energy densities of burns were kept low. Krypton wavelengths are transmitted more effectively to the pigment epithelium and choroid. Therefore, the use of relatively lower and therefore safer power densities compared with the argon laser should suffice for the treatment of diseases at this level.

Argon↗
PubMedDate not supplied

Hyperopic shift induced by high altitude after radial keratotomy.

BACKGROUND: The collagen fibrils embedded in the ground substance of the stromal lamellae provide the structural support for the cornea. When the stromal lamellae are cut in a radial keratotomy surgical procedure, the remaining uncut lamellae carry the tensile forces. METHODS: We studied two expert climbers who had bilateral radial keratotomy before participating in six climbs of extreme altitude, including Mount McKinley and above 7500 m (24,606 ft) on Mount Everest. RESULTS: Whenever either climber was exposed to altitudes greater than approximately 5000 m (16,405 ft) for more than a day, their refraction would become +3.00 D or more hyperopic and remain so al long as they were at or above this altitude. Visual acuity slowly returned to normal after descent. CONCLUSION: It appears that in the presence of significantly reduced atmospheric pressure and/or oxygen there is a greater effect of radial keratotomy in some patients, making the cornea more vulnerable to changes in shape. The cornea appears to respond by further flattening, exacerbating the intended surgical effect and producing a refractive shift toward hyperopia.

Adult↗
PubMedDate not supplied

Corneal ulcers associated with Goldenhar syndrome.

Two patients with Goldenhar syndrome developed corneal ulcers. Previous acid burn of the cornea and prolonged topical corticosteroid administration occurred in Patient 1. Predisposing ocular anomalies in patients with Goldenhar syndrome include corneal hypesthesia; keratoconjunctivitis sicca, and exposure secondary to eyelid colobomas, lacrimal gland and duct anomalies, dermoids and lipodermoids, and neurologic deficits. Serious ocular morbidity may be prevented by searching for and adequately treating these predisposing factors. It is possible that embryonic events contribute to ocular complications in Goldenhar syndrome, in part, by causing hypoplasia or abnormal function of the trigeminal and facial nerves.

Abnormalities, Multiple↗
PubMedDate not supplied

Clofazimine-induced bull's-eye retinopathy.

Bull's-eye retinopathy has multiple associations. We report a case of bull's-eye retinopathy presumed to be secondary to clofazimine (Lamprene) treatment of a 30-year-old patient with acquired immunodeficiency syndrome (AIDS). Pretreatment baseline eye exam of this patient was normal except for bilateral cotton-wool spots. However, follow-up exam 5 months later revealed bilateral anterior pigmentary corneal deposits in a whorl pattern, a presumed infectious retinitis in the left eye, and bilateral annular macular pigmentary abnormalities. The patient was taken off clofazimine treatment, but died 1 month later. The authors suggest that patients being treated with clofazimine be examined for drug-related corneal and retinal lesions.

Acquired Immunodeficiency Syndrome↗