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Biomedical subjects

M Sundaram

Publications and source records attributed to M Sundaram.

At least 271 records · Page 15Linked to original sources

Demonstration of unsuspected malignant disease of the pericardium by computed tomography.

Massive pericardial effusion associated with mediastinal neoplasm was first diagnosed by findings at computed tomography (CT) in two patients. In each case the CT findings prompted urgent pericardiocentesis for relief of pericardial tamponade. One of the patients was subsequently found to have a widely disseminated renal papillary adenocarcinoma, and the other had fibrosarcomatous mesothelioma of the pericardium. The role of CT in the diagnosis of pericardial disease is discussed.

Adenocarcinoma, Papillary↗

Sex-influenced expression of Madelung's deformity in a family of dyschondrosteosis.

Dyschondrosteosis is a mesomelic form of short stature which occurs in conjunction with a characteristic wrist deformity. Madelung's deformity. A family with dyschondrosteosis had an affected father and two daughters. The affected females had dyschondrosteosis and Madelung's deformity, while the affected males had dyschondrosteosis, but no Madelung's deformity. All affected members had arthralgias. The occurrence of male to male transmission confirms an autosomal dominant inheritance pattern for this disorder.

Adult↗

CT in localization of impalpable cryptorchid testes.

Computed tomography was used for preoperative localization in 12 patients with undescended testes. Because three patients had bilateral involvement, 15 absent or undescended testes were studied. Surgical confirmation of the CT findings was obtained in 12 instances. Confirmation was not obtained in one patient who refused operation and it was considered incomplete in another due to limited surgical exploration. There was one incorrect localization. The procedure is quick, simple, noninvasive, and can be performed at all ages. The testicular radiation exposure was considered acceptable on the basis of phantom measurement. The lowest possible exposure factors were used on all patients. CT findings assisted planning of operative procedures and in some cases enabled more limited and shorter operations.

Adolescent↗

Terminal phalangeal tufts: earliest site of renal osteodystrophy findings in hemodialysis patients.

Direct magnificaiton of the hands of 44 patients on maintenance hemodialysis showed that the earliest unequivocal changes of renal osteodystrophy occur in the tufts. Some workers made a similar observation, but no previous objective study confirmed or refuted the sensitivity of the tufts in the diagnosis of renal osteodystrophy. The macroradiograph is consistently reproducible and serves as an excellent visual record of subtle changes.

Chronic Kidney Disease-Mineral and Bone Disorder↗

CT as a primary diagnostic method in evaluating intraabdominal abscess.

In 19 cases, a correct diagnosis of intraabdominal abscess was made by CT body scanning. There was one false-positive diagnosis and initially one false-negative diagnosis. CT proved to be an efficient imaging method for diagnosis, for planning of therapeutic procedures, and in monitoring response to operative or conservative treatment. It has advantages over ultrasound and gallium scanning especially in severely ill, postoperative, and obese subjects. In addition, needle aspiration under CT control is readily performed and can be undertaken at the same examination. Confirmation of the diagnosis and therapeutic aspiration with or without introduction of a drainage catheter can then be undertaken.

Abdomen, Acute↗

Angiographic demonstration of non-occlusive hepatic infarction with scintigraphic and microscopic correlation.

The angiographic appearances of histologically proven hepatic infarction without vascular occlusion has not, to our knowledge, been previously described. A case of non-occlusive hepatic infarction in a diabetic patient is presented and correlated with scintigraphic and microscopic findings. It would appear to be the first recorded case of hepatic infarction associated with diabetic ketoacidosis. A follow-up angiogram showed resolution. The literature is briefly reviewed.

Adult↗

Intestinal bypass: a modification.

Six hundred sixty-four patients who have had metabolic intestinal surgery for the treatment of morbid obesity are reviewed. Particular attention is directed to difference in weight loss, morbidity and mortality in end-to-side and end-to-end shunts, the former performed in 300 patients and the latter in 262 patients. Unsatisfactory weight loss was observed in 20% of patients with end-to-side shunts, while only 8% of patients with end-to-end shunts failed to lose a sufficient amount of weight. Morbidity and mortality were significantly increased in this latter group. This led to adoption of a modification of the end-to-side operation by developing a plication ?REVENT REFLUX. Our preliminary observation indicates that in 102 patients who have had this operation, similar weight loss is attained to that of end-to-end shunts with no greater morbidity or mortality than the end-to-side type.

Humans↗

Uncommon sphenoidal fractures and their sequelae.

Eight cases with fractures of the sphenoid bone are discussed. In four the sella turcica was involved. One showed bilateral fractures of the medial pterygoid plates resulting in an open-bite deformity. Another patient exhibited bilateral carotid-cavernous fistulae. This brings the total of documented, angiographically demonstrated, post-traumatic, bilateral, carotid-cavernous fistulae to seven. Fractures of the planum sphenoidale, the floor of the sphenoid sinus, and bilateral fractures of the lesser wings are also shown. The anatomy of the sphenoid bone and clinical sequelae are briefly discussed.

Adolescent↗