Biomedical subjects

M Sundaralingam

Publications and source records attributed to M Sundaralingam.

At least 181 records · Page 10Linked to original sources

PubMed1971

Stereochemistry of nucleic acids and their constituents. XIX. Copper binding sites and mechanism of G-C selective denaturation of DNA. Crystal and molecular structures of guanine-copper(II) chloride and cytosine-copper(II) chloride complexes.

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Binding Sites↗

PubMed1971

Stereochemistry of nucleic acids and their constituents. XVII. Crystal and molecular structure of deoxycytidine 5'-phosphate monohydrate. A possible puckering for the furanoside ring in B-deoxyribonucleic acid.

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Chemical Phenomena↗

PubMed1971

X-ray diffraction patterns of transfer RNA consistent with the presence of short parallel helices in the molecule.

X-ray diffraction data of yeast formylmethionine transfer RNA, Escherichia coli phenylalanine transfer RNA, and Escherichia coli arginine transfer RNA single crystals are compared with the Fourier transform of a helix. The results are consistent with the presence of short parallel double helical segments in the transfer RNA molecules.

Arginine↗

PubMed1971

The crystal structure of N 6 -( 2 -isopentenyl)-2-methylthioadenine, a modified base of tRNA with cytokinin activity.

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Adenine↗

PubMed1971

Molecular conformation of dihydrouridine: puckered base nucleoside of transfer RNA.

The crystal structure of dihydrouridine hemihydrate has been determined by x-ray diffraction. Crystals of dihydrouridine contain two independent molecules in the asymmetric unit and a molecule of water. The x-ray structure determination has shown that the conformations of both molecules differ in important respects in the saturated base and the ribose. The molecular conformation of dihydrouridine has, for the first time, provided structural evidence that the rare nucleoside can proinote "loop" formation in the sugar-phosphate chain.

Molecular Biology↗

PubMed1971

Stereochemistry of nucleic acids and their constituents. XV. Crystal and molecular structure of 2-thiocytidine dihydrate, a minor constituent of transfer ribonucleic acid.

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Crystallography↗

PubMed1971

Mercury binding to nucleic acids. Crystal and molecular structures of 2:1 complexes of uracil-mercuric chloride and dihydrouracil-mercuric chloride.

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Binding Sites↗

PubMed1971

Stereochemistry of nucleic acids and their constituents. X. Solid-state base-stacking patterns in nucleic acid constituents and polynucleotides.

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Crystallography↗

PubMed1971

Stereochemistry of nucleic acids and their constituents. 18. Conformational analysis of alpha nucleosides by x-ray crystallography.

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Crystallography↗

PubMed1970

Stereochemistry of nucleic acids and their constituents. XI. The molecular structure and conformation of alpha-pseudouridine monohydrate, an unusual nucleoside with a "glycosidic" carbon-carbon bond.

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Chemical Phenomena↗

PubMed1970

Stereochemistry of nucleic acids and their constituents. XII. The crystal and molecular structure of alpha-D-2'-deoxyadenosine monohydrate.

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Binding Sites↗

PubMed1970

Stereochemistry of nucleic acids and their constituents. 13. The crystal and molecular structure of 3'-O-acetyladenosine. Conformational analysis of nucleosides and nucleotides with syn glycosidic torsional angle.

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Binding Sites↗

PubMed1970

Molecular structures of amino acids and peptides. I. The crystal structure and conformation of DL-O-serine phosphate monohydrate. Very short phosphate-phosphate hydrogen bonds.

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Crystallography↗

PubMed1970

Molecular structures of amino acids and peptides. II. A redetermination of the crystal structure of L-O-serine phosphate. A very short phosphate-carboxyl hydrogen bond.

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Crystallography↗

PubMed1970

Stereochemistry of nucleic acids and their constituents. VI. The crystal structure and conformation of dihydrouracil: a minor base of transfer-ribonucleic acid.

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Crystallography↗

PubMed1970

Effects of 3'-O-aminoacylation and 2'-O-methylation on the conformation of ribonucleosides. The crystal structure of 3'-O-acetyladenosine.

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Amino Acids↗

PubMed1970

Biological membrane structure. II. A detailed model for the retinal rod outer segment membrane.

A model, based on the available chemical, electron microscopic, and x-ray diffraction data, has been developed for the structure of the retinal rod outer segment membranes. The model consists of a double layer of globular protein molecules, with lipid bilayer filling the spaces between the proteins. The electron density across the membrane has been calculated and shown to be in agreement with that found by x-ray diffraction. The protein molecules "float" half submerged in a lipid field; this serves to orient them in the same way at all times relative to incident radiation in the intact retina.

Lipids↗

PubMed1969

Stereochemistry of nucleic acids and their constituents. V. The crystal and molecular structure of a hydrated monosodium inosine 5'-phosphate. A commonly occurring unusual nucleotide in the anticodons of tRNA.

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Chemical Phenomena↗