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Biomedical subjects

M Shibayama

Publications and source records attributed to M Shibayama.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Great depth pneumatic caisson and its load work involved with the efficiency of respiratory protection].

Pneumatic caisson work in Japan has been in operation since 1924. Afterward, this technique of compressed air work has been utilized in the constructions like as foundation works, the basements, and shafts of the bottom tunnel or shields for subway and so forth. While, it means for people to be exposed to hyperbaric environment that they use compressed air work, this technique has risks to be suffered from not only decompression sickness (DCS) but toxicity of poisonous gas or oxygen deficiency. However, this technique is necessary for urban civil engineering and recent compressed air works over than 1.0 kg/cm2 has been increased in 1.5 times more than in 1970's and the higher compressed air work more than 4.0 kg/cm2 will be actually planned in near future. So unmanned caisson work is considered as a better technique for such high pressure work, even though people must enter into hyperbaric working fields for maintenance or repair of unmanned operated machinery and materials. This research is to establish the safety work under hyperbaric environment within 7 kg/cm2. It is necessary for us to establish the system not only to keep safety but to maintain working efficiency. According to obtain the purpose, the effect of respiratory protection has been investigated and work load under hyperbaric caisson work has also been studied.

Adult↗
PubMed1989

[A case report of large cell lung cancer detected in the course of antituberculous therapy after a giant bullectomy].

A case of a 60-year-old who male developed lung cancer after surgical resection of a emphysematous giant bulla. At first, he showed a emphysematous giant bulla associated with infected bulla in the right lung on the chest roentgenograph. After a giant bullectomy the resected specimen, suggested possible pulmonary tuberculosis. Thereafter, he was followed for one year with antituberculous therapy. Nevertheless, the chest roentgenograph taken one year after surgery, showed a new tumor density (1.5 x 2.0 cm) in the right lung. Due to the rapid growth of the lung tumor, right upper lobectomy was performed. The histological diagnosis was a large cell lung cancer (giant cell type). The postoperative staging of the tumor proved to be T2N0M0. He was treated with systemic chemotherapy of CDDP 120 mg, VDS 4.5 mg, and MMC 12 mg. Unfortunately, he died of cancer recurrence 5 months after lobectomy. Clinical evaluation of the emphysematous giant bulla associated with lung cancer was performed.

Carcinoma, Small Cell↗
PubMed1987

Consumption of platelets in decompression sickness of rabbits.

Platelet behavior was studied in rabbit decompression sickness which was brought about by the exposure to 6 ATA for 40 min (bottom time) followed by rapid decompression. Platelet counts significantly decreased after the decompression. Kinetic studies with 111In-oxine-labeled platelets revealed shortened survivals of circulating platelets, and audioradiograms indicated the accumulation of radioactivity in the lungs after the decompression. Although there was no change in the mode volume of platelets after the decompression, the transient appearance of circulating smaller or fragmented platelets suggested a random overdestruction of platelets. Whole and releasable adenine nucleotide contents of platelets were decreased significantly after the decompression. There were no significant changes in cytoplasmic adenine nucleotide contents. Therefore, in decompression sickness, the circulating platelets behaved similarly to those in acquired storage pool disease. Platelet thrombi were found in the pulmonary arteries, compatible with the accumulation of 111In-oxine-labeled platelets. These findings suggest that circulating air bubbles interact with platelets, causing the platelet release reaction, and these activated platelets participate in the formation of thrombi in experimental decompression sickness.

Adenine Nucleotides↗
PubMed1987

[A study of eustachian tube function in fishermen (oikomi-gyohoh) divers].

The intranasal pressure at the opening of the auditory tube was compared by Valsalva's method with that of normal adults under atmospheric pressure to find the auditory tubal function of divers often exposed to hyperbaric conditions. It was found that the mean auditory tube opening pressure was higher in professional divers than in normal adults who had never been exposed to hyperbaric pressure. There are two ways of accommodating human auditory tubal ventilation: active opening and passive opening--the former is predominant in adults, the latter in children. The function of professional divers resembles the child type. This finding suggested that they were frequently exposed to a hyperbaric environment, and their auditory tube might not be opened and closed with each swallowing movement under atmospheric pressure, or the auditory tube and the middle ear themselves have been changed into a condition whereby they no longer needed the opening with each swallowing movement might under atmospheric pressure. Moreover, divers take various postures while they are diving, and in rapid dive, they often take a head-down posture. It was obvious that the auditory tube opens less readily in the head-down position. This phenomenon appears to represent the effect of hydrostatic venous pressure in water.

Adult↗
PubMed1987

[Research on the incidence of decompression sickness in compressed air works. The development of its recent five years' study].

Compressed air works have been used as the safest construction work for the basic underground or underwater compressed shield or caisson works in Japan; however, the workers who were exposed to the compressed fields must have put themselves at risk of decompression sickness. Decompression sickness is generally considered to be due to the bubble effects and the bubbles originate from the supersaturated gas dissolved in the blood and other tissues. The standard decompression schedule by the Ministry of Labor has been practically applied at the end of compressed air works, and the laborers decompress slowly from the bottom pressure to the surface according to the schedule. It is difficult to completely prevent the sickness and the average percentage of contracting "bends," using the Japanese standard decompression schedule, is considered to be 0.54%. But previous papers reported higher incidences from 1.42 to 3.3% or more. We have continued an actual investigation on the incidence, and the number of the exposed trials amounted to nearly a hundred thousand. These data were compared between recent five years' group and before. Eventually, it was ascertained that the incidence has been significantly decreased in the recent five years; however, greater care in occupational safety control is still needed.

Adult↗
PubMed1987

[Medical aspects of the environmental sanitation of workplaces in compressed air work in Japan].

Actual follow-up investigations were made for a period of 5 yr and 10 months since February 1980 on 55 places of caisson and shield work. The maximum bottom pressure in caisson work was 3.6 kg/cm2 (4.6 ATA) and that of shield work was 1.6 kg/cm2. The number of exposures of workers was 23,737 in caisson work and 75,244 in shield work. The items of geomedical measurements were temperature (degrees C), humidity, dust, illumination, noise, oxygen, carbonic acid gas and others. In compressed air work, it is most important to prevent decompression sickness (bends) from the view of occupational health. The incidence of bends has decreased in recent years because of strict control by regulations. Environmental hygiene, however, has seldom been discussed in this field and little geomedical control has been made on compressed air work. In view of this situation, we have, therefore, studied, observed, and measured the hygienic factors of this work during the past five years. This investigation is without doubt the first of its kind in Japan and the areas covered most of the regions where compressed air works have been made in the past. From these results, it can be concluded as follows: The working temperature was controlled, but humidity was too high (nearly 90%). Illumination was insufficient. Dust was a problem, but high humidity played an important role in decreasing the volume. The environment was noisy. It is therefore natural that environmental studies should be continued and hygienic consideration be further emphasized in compressed air work.

Atmospheric Pressure↗
PubMed1982

Evaluation of different decompression schedules by an agarose gel bubble technique.

It is well known that diving decompression schedules vary according to country and that Navy schedules are often different from civilian ones. Furthermore, it is difficult to compare them effectively, because the bends incidence for each schedule is rarely known accurately. We have evaluated various decompression schedules by an agarose gel bubble technique in which the appearance of bubbles in a dry chamber at a controlled temperature was used, and we report this as a useful method of evaluating decompression tables. It is generally accepted that decompression sickness symptoms are due to bubble formation and the body's subsequent physiological reaction. Individual differences and physical conditions are also influential factors. However, bubble formation appears to be the most important factor in initiating symptoms. As the number of bubbles is influenced by the physical decompression ratio, it can be estimated which decompression schedule is more likely to minimize the number of bubbles. Nine decompression schedules were studied in this experiment: U.S. Navy Table, French Navy Table, Japanese Standard Decompression Schedule Numbers 1 and 2, Royal Naval Physiological Laboratory Table, French Ministry of Labor Table, Model 1 Table by Mano et al., Washington State Table, and Blackpool Table.

Decompression↗