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Biomedical subjects

M Sh Promyslov

Publications and source records attributed to M Sh Promyslov.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[Practical significance of middle molecules of the blood in assessing the severity of the status of neurosurgical patients].

Study of the content of medium-size molecules (MM), residual nitrogen, creatinine, and urea in the blood of 80 neurosurgical patients with various diseases showed correlation between the severity of the patient's general condition and the MM level. No correlation was noted between the content of MM, creatinine, and urea. The MM level in the blood correlated with that of residual nitrogen in 20% of cases. The MM dynamics may serve as a prognostic sign of the course and outcome of the disease. The MM content corresponds to the severity of the patient's general condition and is not dependent on the etiological and pathogenetic factors.

Adenoma↗
PubMedDate not supplied

[Tryptophan loading and its plasma concentration in neurosurgical patients].

Tests for blood plasma tryptophan in patients with various diseases of the nervous system showed a statistically significant increase of its content in tumors of the astrocytic series in patients with meningiomas and oligodendrogliomas. The character of the tryptophan excretion curve after a load in neurooncological patients was different from that in healthy individuals and patients with thrombosis of the sinus and arachnoencephalitis. Hydrocortisone injection normalized the tryptophan curve in patients and, consequently, also the tryptophanpyrrolase reaction which is evidently disturbed in neurooncological patients.

Arachnoid↗
PubMedDate not supplied

[Concentration of lactate concentration in experimental glial tumors and brain tissue during brief artificial hyperglycemia].

The authors studied the content of lactic acid in glial tumors of the brain and brain tissue of rats in short-term artificial hyperglycemia. In short-term artificial glycemia the lactic acid content in glial tumors of animals was almost twice the level of this metabolite in the brain tissue, which is due to the high potential rate of glucose consumption by the tumor and the increased glycolytic activity in it in these conditions. The lactate content in the glial brain tumors significantly increases when the sugar concentration in the blood of animals is artificially increased. It is suggested that accumulation of lactic acid in brain gliomas of experimental animals contributes to diminution of tumor cell viability, which will increase sensitivity of the tumor to irradiation.

Animals↗
PubMedDate not supplied

[Contents of putrescine, spermidine and spermine in tissue of the human brain glial tumors].

It is shown that in the tissue of the human brain glial tumours the content of putrescine depends on the degree of the tumour malignization. In malignant gliomas (glioblastomas), as compared to the benign (astrocytomas), the content of putrescine is significantly higher. The content of spermidine in glial tumours of a malignancy different degree is twice as high as the level of this polyamine in the brain grey matter, and it is twice as low as in the white matter. The content of spermine in the brain glial tumours does not differ essentially from its level in the brain tissue.

Astrocytoma↗