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Biomedical subjects

M Schiller

Publications and source records attributed to M Schiller.

At least 73 records · Page 4Linked to original sources
PubMed1987

Congenital aneurysms of the deep veins of the lower extremities.

This is a report of our experience with seven children with congenital aneurysms of the deep veins of the lower extremities. All the patients had various clinical features of angiodysplasia. With the use of ascending functional phlebography the patients were divided into two groups: four patients with fusiform aneurysms and three patients with saccular aneurysms. Patients in group 1 had venous reflux and a mild degree of venous insufficiency, which were surgically treated. Three patients with saccular aneurysms (group 2) showed no signs of venous insufficiency and are still being carefully followed. Anatomic and functional assessment of the deep venous system by ascending functional phlebography is essential for planning an appropriate treatment for this rare clinical entity.

Aneurysm↗
PubMed1987

Surgical treatment of infants with esophageal atresia and VATER association.

Our surgical experience in 10 infants with esophageal atresia and the VATER association of multiple congenital anomalies is reviewed. Early recognition and evaluation of the various lesions enabled the planning of a staged surgical approach with a satisfactory outcome. Seven of the patients survived. There were no immediate postoperative deaths. Development and growth curves of the surviving patients are satisfactory. Despite multiple operative procedures infants with VATER association may lead a reasonably normal life.

Abnormalities, Multiple↗
PubMed1986

Varicocele in children: "to treat or not to treat"--venographic and manometric studies.

The management of varicocele is still controversial in spite of its high incidence (15%) in prepubertal boys and young adults and although it is believed to represent a major contributing factor to male subfertility. Fifty boys between 6 and 14 years of age were operated on for left varicocele, and a long segment of the left internal spermatic vein was excised. Thirty-four of them underwent preoperative retrograde left renal venography and pressure readings in both renal veins and inferior vena cava. In all 50 patients, intraoperative antegrade (via internal spermatic vein) left renal venography was performed. This examination revealed impaired renal venous drainage in 38 patients (group A) and normal venous return through the left renal vein in 12 patients (group B). In all 34 patients (from both groups) on whom retrograde venography was performed, there was marked renospermatic reflux. The pressure readings in the left renal vein were significantly increased in group A only. Our data strongly suggest that left varicocele is caused by renospermatic venous reflux and that this condition is probably irreversible. The reflux in group A is explained by the impaired venous drainage through the left renal vein. In group B, it is our impression that the reflux is a result of a congenitally valveless left internal spermatic vein. If varicocele is indeed a major cause for infertility, then our data logically point toward surgery.

Adolescent↗
PubMed1986

Non-iatrogenic deep vein thrombosis of lower extremities in children.

Non-iatrogenic ileo-femoral vein thrombosis is rarely encountered in childhood. Six children with postphlebitic leg following venous thrombosis are presented. Venous thrombosis occurred following peritonitis, osteomyelitis and scarlet fever. None of the patients had history of trauma or intravenous treatment. Based on world literature and our experience, the main clinical and radiological manifestations of this rare entity are summarised. Early detection and aggressive anti-coagulant therapy of deep vein thrombosis may probably prevent post-thrombotic syndrome--a major disabling condition in children.

Adolescent↗
PubMed1986

Congenital aplasia of the deep veins of lower extremities in children: the role of ascending functional phlebography.

Eighty-two children with vascular diseases underwent phlebography. Congenital aplasia of the deep venous system of the lower extremities was diagnosed in 10 children. With ascending functional phlebography, three anatomic variations with different degrees of venous dysfunction were defined: aplasia of the femoral vein with collateral drainage into the common femoral vein, aplasia of the femoral vein with drainage into the internal iliac vein, and total aplasia with drainage into the axillary vein. The phlebographic findings correlated with the symptoms. Patients with type a aplasia had no clinical and radiologic signs of venous insufficiency. Patients with types b and c aplasia had severe venous insufficiency that necessitated supportive treatment. Palliative surgical procedures such as hemorrhoidectomy, clitoridectomy, and excision of bleeding vascular nevi were performed. Ligation or excision of the dilated superficial veins (usually the main channels for venous drainage from the extremity) is absolutely contraindicated. Ascending functional phlebography is therefore essential for correct diagnosis and planning of future therapy.

Adolescent↗
PubMed1985

Hashish extract impairs retention of defeat-induced submissive behavior in mice.

The effects of hashish extract on adaptive behavior of male mice were studied in a paradigm which allows the investigation of learning mechanisms in a social context. Mice of the C3H strain, which were not submissive in a confrontation with a nonaggressive DBA mouse on day 1, were defeated on day 2 over 3 min by aggressive, isolated DBA mice, and showed conditioned submissive behavior upon mere contact with a nonaggressive DBA mouse on day 3. A hashish extract containing 38.6-39.4% delta 9-tetrahydrocannabinol (delta 9-THC), 11.6-12.0% cannabinol and 47.7-48.5% cannabidiol was administered orally in all experiments. Hashish extract given 90 min before defeat on day 2, in dosages corresponding to 1, 5, and 10 mg delta 9-THC/kg, impaired retention of defensive upright, defensive sideways and immobility on day 3 (experiment 1). Experiment 2 showed that the drug (5, and 10 mg delta 9-THC/kg) had no antinociceptive potency in mice and did not modify defeat-induced analgesia. Experiment 3, with drug (5 mg delta 9-THC/kg) or solvent administration on day 2 and day 3, showed that the retention deficit was neither due to state-dependent learning, nor to impaired retrieval. It is suggested that hashish extract administered before learning may interfere with memory processing.

Aggression↗
PubMed1985

Simultaneous superior and inferior vena cava pressure recordings in giant omphalocele repair--a possible guideline for prevention of postoperative circulatory complications.

Eleven children underwent second stage repair of giant omphaloceles containing the liver. Simultaneous SVC and IVC pressure before, during and after closure of the abdominal wall was recorded. In all patients with circulatory complications the SVC pressure decreased following surgery. The postoperative pressure ratios in IVC and SVC (Formula: see text) was found to be four times greater in the group with complications. It is suggested that this ratio might serve as an important index in the prediction of abdominal wall closure feasibility in giant omphaloceles.

Central Venous Pressure↗
PubMed1984

Pericardial tamponade complicating central venous catheterization in a newborn infant.

Complications of central venous catheterizations are divided into immediate or early complications such as haematoma, pneumothorax and haemothorax, and late complications such as infection and venous thrombosis. One of the rare but life-threatening complications of central venous catheterization is pericardial tamponade. We review the literature and add an additional case, the first reported in a newborn infant.

Cardiac Tamponade↗
PubMed1984

Congenital hepatic fibrosis--unusual presentations.

Two children with congenital hepatic fibrosis presented atypically: one with prolonged fever and hepatomegaly associated with a giant intrahepatic biliary cyst and a second with ascites at an early age despite normal serum albumin concentrations.

Ascites↗
PubMed1983

Multiple arterial aneurysms.

An 8 1/2-yr-old boy presenting with excruciating abdominal pain had two abdominal aortic aneurysms excised. Angiography demonstrated additional aneurysms of the right brachial artery, right renal artery, right internal iliac artery and multiple aneurysms of the right popliteal and tibialis posterior arteries. The patient does not suffer from any of the conditions generally recognized to be associated with aortic and multiple arterial aneurysms. No similar case could be found in the English language literature.

Aneurysm↗
PubMed1983

Inferior vena cava anomalies associated with giant omphalocele--a proposed classification.

Thirteen patients with hepatomphaloceles were investigated pre-operatively by an inferior venocavogram as to the shape of the eviscerated liver and the course of the inferior vena cava. Roentgenographic findings correlated with operative findings and three distinct patterns of anomaly were seen. Type 2 and particularly Type 3 are likely to be associated with severe post-operative complications if the peculiar anatomy is not recognized beforehand. We feel that a pre-operative inferior venocavogram and determination of type of anomaly is mandatory in planning the treatment of these patients.

Angiography↗
PubMed1983

Unusual parascrotal hernia with ectopic testicle in a neonate. Case report.

A giant indirect inguinal hernia leading to a huge parascrotal mass in a newborn is described. The right scrotum was empty and the ectopic testicle was found in the perineum, close to the anus. To our knowledge this is the first report of the presence at delivery of a parascrotal inguinal hernia in combination with an ectopic testicle.

Hernia, Inguinal↗