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Biomedical subjects

M Sas

Publications and source records attributed to M Sas.

At least 127 records · Page 7Linked to original sources
PubMed1977

[Obstetric results and problems after induction of ovulation].

Ovulation induction has been used regularly in our department for several years to treat functional sterility. 4. various preparations and methods have been applied. The success rate is 31.3%. Altogether there have been 400 pregnancies, 274 of them have come to term, 126 patients are still pregnant. In 50% of the cases the pregnancy was uncomplicated and in 48.7% labour was normal. The number of abortions and premature labour is high and the prophylactic gestagene therapy has been successful in protecting the pregnancy. There have been more pathologies during labour, so the frequency of interventions is higher. The perinatal mortality of the mature newborn is 2.3%, but the perinatal mortality in premature labour is very high (14.7%). The total perinatal loss is 9.8%. The frequency of malformations is not higher as was previously suspected.

Abortion, Spontaneous↗
PubMed1977

Metabolism of prostaglandin F2alpha in early human placenta in vitro.

The authors were investigating the metabolism of prostaglandin F2alpha in human early placenta, in in vitro incubation experiments. They have identified both major metabolites, 15-keto-PGF2alpha and 15-keto-13,14 dehydro PGF2alpha. They have examined the change in the percentage of these, taken as a function of time. They have established that the main site of inactivating the endogenous PGF2alpha is the early human placenta. They suppose that the considerable Pg-inactiviting effect of the placenta has a part which acts as a protecting mechanism in preventing the uterotonic influence of the endogenous prostaglandins.

Female↗
PubMed1977

Biological significance of human prolactin in adult, healthy and infertile males.

The human prolactin (hP) levels have been studied in adult healthy and infertile males. The hormone level was 8.5--38.0 ng/ml in sperm-plasma and 3.4--32 ng/ml in blood plasma. Values for normo and pathospermic patients showed no significant difference. In normo and hypospermia the hP level was higher in the ejaculate than in blood plasma. There was a close correlation between the hP and fructose levels of the ejaculate, while the correlation between hP and testosterone levels in the ejaculate was not highly significant. There is a certain relationship between the plasma hP and testosterone levels and the sperm count.

Adult↗
PubMed1977

[Increasing the effectiveness degree of ovulation induction using clomiphene in combination with HCG in cases of functional sterility].

The authors gave functionally infertile women a combined treatment, of Clomiphen + HCG whom 19 had already been treated with Clomiphenor Epimestrol without success. If the number of ovulations considerably increase in consequence of Clomiphen + HCG treatment or the periods of ovulations, aphysiological periods, are of physiological duration the treatment may be successful. In these cases the effectiveness of Clomiphene induction can be intensified with HCG administration

Adult↗
PubMed1977

[The importance of hormone examinations in ovulation induction (author's transl)].

Those hormone-determination methods were reported by the authors which help to make the ovary response visible for the experts during the ovulation induction. They also dealt with the determination of basal temperature measuring, oestrogen, pregnandiol, progesterone, oestradiol-17beta, FSH, LH, epimestrol and clomiphen. After the routine determination of the above mentioned parameter a preprinted sheet was done, where every treated case was illustrated graphically. From these cases some of the typical ones were shown and analyzed. The determination of hormonal releasing curves characteristic of hyperstimulation, and the importance of these most dangerous complication was emphasized.

Adult↗
PubMed1975

Significance of transaminase determination in seminal fluid.

GOT activity of the seminal fluid plasma was examined in 161 cases. High values were found in cases with astheno- and necrospermia, and in those with an increased spermatozoon count, low values were found in cases with oligospermia. The authors consider GOT determination in seminal fulid plasma a useful supplemental test in the diagnosis of male sterility.

Aspartate Aminotransferases↗