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Biomedical subjects

M Sas

Publications and source records attributed to M Sas.

At least 109 records · Page 6Linked to original sources
PubMed1978

[Sex education and education for family life in adolescents].

A program of education of college girls and boys between 14--18 years of age for sexual and family life is going on in the Hungarian secondary school. There are 20 lectures within 4 years. The goal and the subjects of the lectures specially designed for each semester are outlined by the author.

Adolescent↗
PubMed1978

[Contraception in children and adolescents].

It is discussed how the adult type contraception fits the divergent needs of the youngsters. Oral contraceptives are suitable from the 16th year of life. Vaginal globuli and foams have also proved to be an effective means of contraception over that period of life. For anatomical reasons pessaries are not recommended, insertion of intrauterine devices is contraindicated because of their possible adverse effects. Experiences with university students taking d-Norgestrel as "morning-after-pill" have been favorable. The therapeutic abortion is regarded as an emergency measure to be employed only if anticonception failed. Adaequate education at the proper age and the importance of preventive measures are stressed.

Abortion, Spontaneous↗
PubMed1978

Mesterolone treatment of patients with pathospermia.

The response to Mesterolone, in doses of 25 mg/day, was examined in 42 pathospermic patients. Treatment lasted for 100 days. The pronounced response to the Mesterolone treatment was observed in hypozoo- and oligozoospermia with low initial fructose content in the ejaculate. Fructose content attained its normal range after the treatment. During the therapeutic period 11 wives became pregnant. The authors conclude that Mesterolone does not influence plasma FSH, LH and testosterone levels, it has only peripheral effects.

Adult↗
PubMed1978

Choriogonin treatment of patients with pathospermia.

The effect of HCG was examined in 160 infertile patients. The first group of patients (100 men) received 1500 I.U. HCG twice weekly for 8 weeks, the second group (60 men) was given 1500 I.U. HCG twice weekly for 12 weeks. Serum testosterone level was found to be increased after treatment in 44 cases. Improvement was reported on potentia coeundi. The spermiogram improved in 34% of the cases. During the period of treatment 25 wives became pregnant.

Adult↗
PubMed1978

Effect of LH-RH loading in subfertile men.

Thirty-two infertility patients were studied to evaluate the response of plasma FSH and LH to intravenous injection of 100 microgram synthetic LH-RH. Initial LH and FSH levels were taken into consideration in evaluating the responses. While the LH response was usually more pronounced, it seemed more valuable, from the prognostic point of view, to examine the FSH changes because of their applications to the diagnostic and prognostic processes.

Cell Count↗
PubMed1978

Suppression of uterine motor activity by prostaglandin synthetase inhibitor Naproxen.

Rats were ovariectomized on day 16 of pregnancy and they were fitted with a pressure sensor uterine microballoon assembly and were given a daily dose of Naproxen-sodium. Daily uterine activity recordings were taken and subjected to statistical analysis and the rats were carefully checked for either aborting or delivering their fetuses. Our data showed that Naproxen treatment effectively and significantly prevented the autocatalytic evolution of the uterine motor activity and the regulatory "see-saw" of progesterone and prostaglandins was rebalanced at a lower level.

Animals↗
PubMed1978

[Treatment of hyperprolactinemic conditions with bromoergocryptine].

Ten hyperprolactinemic patients were treated by a daily dose of 5 mg bromergocryptine (Parlodel, Sandoz). The prolactine concentration in the peripherial blood showed a fast declind and after two months the patients were relieved from the symptoms (galactorrhea, amenorrhea). As side-effects of the compound headache and nausea were noted.

Adult↗
PubMed1978

Postconceptional prostaglandin therapy.

392 cases of prostaglandin abortions were analyzed for efficacy, clinical acceptability and complications. It was repeatedly emphasised that the clinical administration of PGs are not without risks and serious drawbacks. The vaginal suppositories seem to be vary promising. It is suggested that new lines of research should be pursued in order to improve our understanding of the effect of PGs and to develop better dose schedules as demanded by clinical and professional excellence.

Abortion, Induced↗
PubMed1978

In vitro prostaglandin biosynthesis in human pregnant uterus from arachidonic acid.

Formation of prostaglandins (F2alpha, E2 and D2) in the pregnant human uterus microsomes was studied using 14C-labeled arachidonic acid. Sample of uterine pieces were removed from the lower uterine segment at the time of Caesarean section. The prostaglandin synthesis in the microsomal fraction was characterized in terms of cofactors, substrate concentration and incubation time requirements.

Arachidonic Acids↗
PubMed1978

Steroid levels in the serum and seminal plasma during clomiphene therapy in hypofertile men.

The serum and seminal plasma concentrations of androstenedione, testosterone, dihydrotestosterone and 17beta-oestradiol were investigated in hypo- and oligospermic males during clomiphene-citrate, administration. A significant increase was demonstrated in the serum testosterone, dihydrosterone and 17beta-oestradiol values, mainly in the first month of therapy. The steroid increase in the ejaculate was less pronounced. Measuring of 17beta-oestradiol in serum appears to be a useful parameter for estimating the stimulative effect of clomiphene citrate.

Androgens↗