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Biomedical subjects

M Sarr

Publications and source records attributed to M Sarr.

At least 91 records · Page 5Linked to original sources
PubMed1997

[Electrocardiographic changes in chest deformities. Apropos of 20 cases in black subjects].

The objective of this study is to describe the electrocardiographic signs associated with certain chest deformities. This is a prospective, case-control study comparing 20 black subjects with chest deformity (11 cases of flat back syndrome, 5 cases of pigeon chest, 4 cases of funnel chest) with 20 age- and sex-matched healthy controls. Cardiac duplex ultrasound was performed for each individual to exclude associated heart disease. Atypical electrocardiographic signs were observed in 15 subjects with chest deformity versus only 3 in the control group. The anomalies observed consisted of signs of atrial or ventricular hypetrophy, right branch block, abnormalities of repolarization on the T wave or ST segment. Chest deformities are therefore associated with several electrical signs simulating most cardiac diseases. A good knowledge of these modifications should help to avoid the numerous diagnostic traps associated with these signs.

Adolescent↗
PubMed1997

[Echocardiographic data from chronic dialysis patients in Dakar].

The authors report the results of a prospective study about echocardiographic parameters of 14 chronic dialyzed patients. Mean age was 44.4 +/- 12 (extremes: 16 and 63). There are 12 men (86%) and 2 women (14%). The main renal disease responsible was nephroangiosclerosis (9 cases, 64.3%). Hypertension is found in all the patients, anemia in 13 (92.8%). The heart, as shown by echocardiography, was concerned in 13 patients (92.8%). The main abnormalities found were: left ventricular hypertrophy (13 cases: 92.8%), left ventricular dysfunction (4 cases: 28.5%), abnormality in left ventricular relaxation (3 cases: 21.4%), pericardial effusion (4 cases: 28.5%).

Adolescent↗
PubMed1997

[Role of beta-blockers in the treatment of mitral stenosis, apropos of 4 cases].

The use of beta blockers during treatment of mitral stenosis is discussed on four cases involving females patients who are symptomatic. All had sinusal tachycardia, one was pregnant, one with cardiothyreosis, two with anemia. In all cases, it's the use of beta-blockers with diuretic, veinous vasodilator and digitalic drugs that allowed the successful treatment of the pulmonary oedema. These observations, added with the literature study, showed that beta-blockers treatment is wise when the subject is carefully studied. The best result is obtained on pure mitral stenosis without left ventricular systolic dysfunction, with sinusal tachycardia and high cardiac output state.

Adrenergic beta-Antagonists↗
PubMed1997

[A baobab solution for the prevention and treatment of acute dehydration in infantile diarrhea].

OBJECTIVE: The purpose of this study was to compare the clinical efficacy of a local solution based on "pain de singe", fruit of baobab (Adansonia digitata), and the WHO standard solution in the treatment of children with acute diarrhea and resulting mild to moderate dehydration. METHODOLOGY: A prospective clinical trial comparing the local solution to the standard WHO solution was conducted; in children of 6 months or older (mean age = 16.6 +/- 8.8 months), 79 received the WHO solution and 82 the local solution, and were followed for a period ranging from 4 to 48 hours. Evolution of diarrhea and weight gain were evaluated as variables of interest. RESULTS: WHO solution was found to be superior, but not statistically significant in term of duration of diarrhea and weight gain. DISCUSSION: The pain de singe based solution presents additional advantages: nutritional, economic and cultural; we recommend it to promote use of TRO at home.

Bicarbonates↗
PubMed1997

Cclinical study of vscular risk factors in the adult in the Thiadiaye rural environment.

Authors report the results of a prospective study in a sample of the district of Thiadiaye, a rural area in Senegal. They studied blood pressure, body mass index and waist-to-hip ratio of 329 adults. The mean systolic blood pressure is 123 +/- 24.3 mm Hg and the mean diastolic blood pressure is 71.7 +/- 13.2 mm Hg. There is a positive correlation between blood pressure and age (p < 10(-9)). The prevalence of hypertension is 20.18% and one can note a female predominance (21% for women versus 18% for men). The mean body mass index is 21.1 +/- 10.6. There is no correlation between corpulence and age. Conversely, the body mass index is higher in female in all age groups (p < 10(-7)). The prevalence of obesity is 5%. Abdominal fat distribution is 41.6%: 64% for women and 9.7% for men (p = 0.003).

Adipose Tissue↗
PubMed1997

[Tetralogy of Fallot. Anatomo-clinical, prognostic and therapeutic features].

Between Feb. 1992 and Aug. 1995 during a prospective study Tetralogy of Fallot (TF) has been diagnosed in 34 children among 207 with congenital heart disease (CHD). Our purpose is to assess prevalence of TF among CHD, to analyse clinical and paraclinical aspects in patients with TF and to point out associated abnormalities in that disease. In all patients diagnosis was made by echocardiography-Doppler (ATL MK 600). In our patients with CHD, TF represent the third abnormality encountered accounting for 16.49% after ventricular septal defect (30.9%) and persistent ductus arteriosus (18.8%). Mean age of patients with TF is 8.36 years. History showed cardiopathy in the family of one patient. The brother had persistent ductus arteriosus. In our patients with TF, clubbing is present in 70.58% of the cases, cyanosis in 79.41% and squatting in 76.47%. Anoxic spells are present in six patients. On chest x-ray mean cardio-thoracic ratio is 0.57 +/- 0.076. On ECG mean QRS axis is +121 +/- 22.91 degrees. In one patient with Cornélia Delange syndrome TF is associated with complete endocardial cushion defect. Mean follow-up is 332,42 days. Endocarditis on the pulmonary valves is present in one case. Four patients died after complications. Because of poor clinical tolerance and complications, surgery is indicated for all our patients. Only 7 patients underwent surgery. Two of them were operated in Dakar. There was two postoperative complications, one patient had brain abscess which necessitate reoperation, and the other had hypertension in the right ventricle and atrial right to left shunt. Our study shows that TF is an important nosologic group. In our country this frequent malformation have a poor prognosis in the majority of cases because late detection and frequent complications. Because palliative surgery for TF is now available in Senegal prognosis of the patients is going to improve. Future Development of open heart surgery will offer a corrective approach for patients with TF in Senegal.

Anemia↗
PubMed1997

[Complete D-transposition of the great vessels diagnosed late in a 10-month infant. Rashkind manoeuvre].

We report a first documented case in Senegal with simple transposition of the great arteries diagnosed in a 2 months old girl treated by Rashkind atrioseptostomy. Our patient benefited from clinical examination, ECG (15 derivations), chest X ray and standard laboratory tests. Pulsed-Doppler, two dimensional and TM echocardiography have been performed with an ATL MK 600 echocardiograph. Cardiac catheterism, angiocardiography and Rashkind procedure have been realized in our Department. These data are discussed and compared to the literature. At admission this patient presents with major cyanosis and polypnea. At examination, there is a 3/6 murmur at the left sternal border and a subclavicular continuous murmur. Laboratory tests showed metabolic acidosis and severe hypoxemia. Chest x-ray showed a cardio-thoracic ratio at 0.64 with increased pulmonary vascular markings. ECG showed right ventricular hypertrophy. Echocardiography-Doppler revealed ventriculo-arterial discordance with restrictive atrial septal defect and persistent ductus arteriosus. Rashkind procedure was followed by an increased aortic saturation. After 6 weeks there was an improvement of cyanosis and cardiac failure. Diagnosis of transposition of the great arteries is actually easier with development of ultrasonography which is useful when performed by experienced cardiologist. Spontaneous prognosis of this malformation is very poor. Rashkind atrioseptostomy is an important step for the initial treatment of transposition of the great arteries in terms of survival before open heart surgery.

Cardiac Catheterization↗
PubMed1996

[Congenital heart disease surgery in Senegal. Indications, evaluation and perspectives].

In Senegal, congenital heart diseases (CHD) raise important issues. Their late detection makes more complicated the non yet resolved issue of the medico-surgical care. 108 patients with congenital heart diseases have been studied prospectively from February 1992 to May 1994. Epidemiological, clinical, paraclinical data are analysed. Prognosis and treatment are discussed. Congenital heart diseases represent 1% of the outpatient cardiovascular pathology. Diagnosis of the malformation based on echocardiography shows that most of congenital heart diseases are ventricular septal defect (25%); followed by Tetralogy of Fallot (13%). Average age of the patients is 6.86 years. 31% of the cases have heart failure. ECG is abnormal in 103 patients. On the radiologic side, average cardio-thoracic ration is 0.61. Because of heart failure, pulmonary hypertension and hypoxia, the spontaneous prognosis is cautious in 71 patients (66%) who should receive surgical treatment. Among them, 5 patients non operated died and 10 (14%) have been operated. Among the 10 patients who got surgery, 3 with wide persistent ductus arteriosus got in Dakar. All these patients have excellent operative results. In Senegal, only close heart surgery is available and prognosis of the vast majority of patients, including those with valvular and coronary heart diseases, is very cautious. Intervention of Europe-based aid organizations for evacuation is not useful. It is very important to promote, in Senegal, open heart surgery.

Adolescent↗
PubMed1996

[Rupture of a sinus of Valsalva aneurysm into the right ventricle. A case report in the cardiology clinic at the University Hospital Center of Dakar].

We report a case with ruptured aneurysm of the sinus of Valsava into the right ventricle, diagnosed during heart failure in a 22 years old patient. Etiology and prognosis based on our observation and the literature are discussed. Our patient benefited from clinical examination, ECG (15 derivations), pulmonary X ray and standard laboratory test. Pulsed-Doppler and contrast echocardiography have been realized with an ATL MK 600 echocardiograph. These data are discussed and compared to the literature. Cardiac examination revealed a continuous murmur predominantly diastolic 5/6 and an increase of peripheral artery pulsatility. Chest x-ray showed cardiomegaly and ECG bilateral atrial and left ventricular hypertrophy. Two-dimensional echocardiography revealed the diastolic prolapse of an aneurysmal right coronary sinus in the right ventricle. The rupture was confirmed by contrast echocardiography and pulsed-Doppler. Rupture which is a major complication of aneurysm of the sinus of Valsava, is the usual feature of detection. The consequences of rupture are heart failure and pulmonary edema. Our observation shows that conventional Doppler and contrast echocardiography are important for diagnosis and follow-up of aneurysm of the sinus of Valsava. Aortography, hemodynamic and angiocardiographic data, are also important for a precise diagnosis and the detection of associated malformations when pre-operative investigations of aneurysm of the sinus of valsava are needed.

Adult↗
PubMed1995

[Left ventricular aneurysm of indeterminate etiology revealed by an episode of ventricular tachycardia].

INTRODUCTION: We present a case history of a 39 years old woman with parieto-apical left ventricle aneurysm of unknown etiology. The etiologies are being discussed in the light of our case and literature review. METHODS: We have analysed clinical data, 12 leads ECG recording, chest X-ray and biological data of our patient. We have used an ATL MK 600 for echo-Doppler examination. Coronaro-ventriculography has not been performed. The results are compared with data from the relevant literature. RESULTS: Our patient presents at admission tachycardia (150 beat per min) and congestive heart failure. ECG recording showed a sustained tachycardia with large QRS complex (140 msec). At oesophageal ECG recording, atrio-ventricular dissociation was present confirming ventricular tachycardia. The tachycardia has been stopped by lidocaine and amiodarone IV. Chest X-ray shows cardiomegaly (cardio-thoracic index: 0.70) and a protruding left cardiac border. At echocardiographic examination a left dyskinetic anterior and apical aneurysm of the left ventricle has been documented. Surgical repair has not been performed because of the large aneurysm and the reduced function of the non aneurysmal contractile zones. CONCLUSION: In our case, myocardial infarction was not evident, regarding history and examinations. In the etiologic discussion of left ventricle aneurysms, coronaro-ventriculography must be performed. Dilated cardiomyopathy complicated by left ventricle aneurysm can be postulated in our patient.

Adult↗
PubMed1995

[Arterial hypertension in Senegal: epidemiological aspects, clinical features, and therapeutic management problems].

The authors report the results of a bunch of studies about hypertension in Senegal: a retrospective study concerning 868 patients in the cardiologic center; a prospective study on 2329 subjects in Pikine, a Dakar Suburb; a study led near 121 physicians about their dealing with hypertension problems. Hypertension is the second reason of hospitalization in cardiology just after the rheumatic cardiopathy. The mortality rate is 6.35%. The hypertension frequency in the suburb is 10.43% (certified hypertension) and 25.03% (borderline to certified). The same frequency is found between males and females patients. This frequency grows with the body mass index and age. Many problems occur concerning the treatment: lack of proper following (39%), failure of the therapy (39%), inappropriate reduction of physical activities (82.5%), strict ban of any salt intake for mild to moderate hypertension (13.18%).

Adult↗
PubMed1995

[Congenital cardiopathies: anatomo-clinical, prognostic, and therapeutic features apropos of 103 cases seen at the Cardiology Clinic of the Dakar University Hospital Center].

We have studied retrospectively 103 patients with congenital heart disease from july 1989 to december 1991. The mean age is 7.8 years +/- 8.6. Epidemiological factors, clinical, morphological and prognostic data have been reviewed. All the patients had been evaluated with echocardiography based on an anatomical and segmental approach. Sex-ratio is 1.11. Situs is solitus in 101 cases (98%). Atrio-ventricular connexions are concordant in 97 patients (94%). The ventriculo-arterial connexions are concordant in 91 patients (88%). We found an anomaly of the spatial relation between great vessels in 9 cases (8.7%). Echocardiographic diagnosis have been confirmed by catheterism and at surgery in 10 patients, and by post-mortem examination in 2 cases. Isolated ventricular septal defect is the most frequent anomaly (19.4%), followed by Tetralogy of Fallot (17.5%). Only 13 patients among the 75 (17.3%) needing surgery have been operated. Six patients (5.8%) died following complications of the malformation. The prognosis without surgery is poor for the majority of our patients with congenital heart disease. Improved early detection and acquisition of adequate diagnosis technology are needed to realize surgical corrections.

Adolescent↗
PubMed1995

[Low birth weight: rate and risk factors in the Guédianwaye district (suburb of Dakar, Senegal)].

The authors report the results of a six months survey about the low weight of birth (L.W.B.) in the district of Guédiawaye, suburb of Dakar. The purpose is to determine the rate of L.W.B. in two main maternity hospitals of that locality and the associated risk factors. It is a survey with a control group. This survey results in a 10.7% rate, according to the data of another retrospective survey in the same maternity hospitals in 1992 (10.03%). The risk factors are mainly: celibacy, primiparity, an associated pathology with the pregnancy, the physical strain of mothers correlated to the income and to the previous L.W.B.

Adolescent↗
PubMed1994

[Non typhoidic salmonellosis in the African pediatric population].

The study of non-typhoidic salmonellosis in A. royer pediatric Hospital (Dakar) during a five year term (1985-1989) was realised on thirty five medical records. This pathology accounts for 0.4% of admissions and occurs mainly on children under 3 years old (83%) essentially with a pathologic background. The main clinical forms were septicemia (46%) and gastro-enteritis (31%). Purulent meningitidis represented 45% of all the localized forms. Only one case of asymptomatic carriage has been identified. The seventeen serotypes of Salmonella identified belong to eight serogroups. S. enteritidis and S. typhimurium represented 51% of the isolates. Susceptibility to antibiotics of these different serotypes were variable, the third generation cephalosporins and gentamycin having inhibited more than 80% of the strains. The mean duration of antibiotherapy was 21 days with a mortality rising to 17%. The association ampicilline-gentamycin although criticable, remains indication as first treatment because of the availability of these drugs.

Bacteremia↗
PubMed1994

[Place on information in health services use by mothers in Guediawaye].

The authors report the results of a survey in a suburban healthcare structure. The purpose was to evaluate the knowledge of mothers about the healthcare delivered through a childhood and maternal healthcare program in Senegal. 244 women were selected at random. The consultant mothers came more for their children than for themselves (79% of consultations were for their children, 49% for themselves). 60% to 80% of women are unaware of basic notions currently teached through the "Information-Education-Communication (I.E.C)" program. All that requires to elaborate with these women healthcare strategies, which are in adequacy with their needs in these peripheral healthcare structures, and which are supported by an adequate and regularly evaluated I.E.C.

Adult↗
PubMed1994

[Medico-social problems of young adolescents in Guediawaye (suburban area of Dakar-Senegal)].

A survey in the district of Guediawaye, towards teenagers from 12 to 16 years old, recruited according to a stratified risky method of sampling in 4 different areas has been carried out in order to evaluate their main medico-social problems. It ended up to the following findings: the majority live in hard socio-economic conditions stamping by promiscuity, a weak family income and a low level of education of the parents. 39.2% have been placed under the guardianship of a relative other than the parents. 98.8% do not find spare time structures in their environment. The usage of tobacco and drug is respectively 14% and 1%; 79.4% of students have hardly access to the school stationery, while the teenagers in job apprenticeship have constraints linked to long hours of work (95%). The morbid affections are too varied, dominated by stomach aches (37.8%) far before traumatics (6%); the most frequent therapeutic is resort traditional or empiric treatment. The authors advocate the setting up of a medico-social center making interfere all persons, implied resources in the undertake of the teenagers.

Adolescent↗
PubMed1994

[Purulent pleurisy in the child].

We studied 122 cases of empyema in children. The mean age was 3 years. We found malnutrition in 33% of the patients. 60% of them had large pleural effusion and 56% associated pneumonia. Staphylococcus aureus (51%) and Streptococcus pneumoniae (18%) were the most frequently isolated bacterias in pleural fluid. The mortality rate was 6.5%. 53% of the children had closed chest tube drainage. There were minor abnormalities in pulmonary function tests. The best treatment of empyema in children is closed chest tube drainage and an antimicrobial therapy with antistaphylococcus antibiotic.

Adolescent↗